AutismKB 2.0

Annotation Details for CDC27


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Basic Information Top
Gene Symbol:CDC27 ( ANAPC3,APC3,CDC27Hs,D0S1430E,D17S978E,HNUC )
Gene Full Name: cell division cycle 27 homolog (S. cerevisiae)
Band: 17q21.32
Quick LinksEntrez ID:996; OMIM: 116946; Uniprot ID:CDC27_HUMAN; ENSEMBL ID: ENSG00000004897; HGNC ID: 1728
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21241890
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005680IDA-anaphase-promoting complex16364912
GO:0005737IDA-cytoplasm-
GO:0005813IDA-centrosome7736578
GO:0005819TAS-spindle7736578
GO:0005829TAS-cytosol-
GO:0005876IDAcolocalizes_withspindle microtubule7736578
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16648845
GO:0019903IPI-protein phosphatase binding21241890
GO ID Evidence Qualifier GO_term References
GO:0007091IMP-metaphase/anaphase transition of mitotic cell cycle7736578
GO:0008283TAS-cell proliferation7736578
GO:0031145TAS-anaphase-promoting complex-dependent catabolic process-
GO:0042787TAS-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-
GO:0043161TAS-proteasome-mediated ubiquitin-dependent protein catabolic process-
GO:0051436TAS-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0051437TAS-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-
GO:0051439TAS-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-
GO:0070979IDA-protein K11-linked ubiquitination18485873
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
CDC27BUB1B10743110477750 Affinity Capture-Western
CDC27BUB1B10716610477750 Affinity Capture-Western
CDC27CCNB110733212097298 16479161 Affinity Capture-Western
CDC27CCNB110743112097298 16479161 Affinity Capture-Western
CDC27CDC201074279628895 9736712 9811605 12196507 12956947 14561775 16479161 18997788 Affinity Capture-Western; Reconstituted Complex
CDC27CDC201074319628895 9736712 9811605 12196507 12956947 14561775 16479161 18997788 Affinity Capture-Western; Reconstituted Complex
CDC16CDC271144009405394 9628895 10922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
CDC16CDC271074319405394 9628895 10922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
PPP5CCDC271115289405394 Reconstituted Complex
PPP5CCDC271074319405394 Reconstituted Complex
PIN1CDC271113179499405 10037602 Affinity Capture-Western; Far Western
PIN1CDC271074319499405 10037602 Affinity Capture-Western; Far Western
MAD2L1CDC271074319628895 9736712 Affinity Capture-Western
MAD2L1CDC271102609628895 9736712 Affinity Capture-Western
FZR1CDC271194899811605 12097298 12797865 Affinity Capture-Western
FZR1CDC271074319811605 12097298 12797865 Affinity Capture-Western
ANAPC10CDC2711566510922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC10CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
CDC26CDC2712887810922056 14657031 Affinity Capture-MS; Affinity Capture-Western
CDC26CDC2710743110922056 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC4CDC2711898210922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC4CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC5CDC2711953710922056 12956947 14657031 15082755 Affinity Capture-MS; Affinity Capture-Western
ANAPC5CDC2710743110922056 12956947 14657031 15082755 Affinity Capture-MS; Affinity Capture-Western
ANAPC7CDC2711953810922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC7CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC11CDC2711959110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
ANAPC11CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
CDC23CDC2711424210922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
CDC23CDC2710743110922056 12956947 14657031 Affinity Capture-MS; Affinity Capture-Western
APC2CDC2710743110922056 12956947 Affinity Capture-Western
ANAPC1CDC2712222911076961 12956947 Affinity Capture-Western; Co-purification
ANAPC1CDC2710743111076961 12956947 Affinity Capture-Western; Co-purification
SMAD2CDC2711026211691834 Affinity Capture-Western
SMAD2CDC2710743111691834 Affinity Capture-Western
SMAD3CDC2710743111691834 Affinity Capture-Western
SMAD3CDC2711026311691834 Affinity Capture-Western
TTKCDC2710743112686615 Affinity Capture-Western
TTKCDC2711312312686615 Affinity Capture-Western
CDH1CDC2710743112956947 16479161 Affinity Capture-Western; Reconstituted Complex
CDH1CDC2710743412956947 16479161 Affinity Capture-Western; Reconstituted Complex
ANAPC2CDC2710743114657031 Affinity Capture-MS
ANAPC2CDC2711893714657031 Affinity Capture-MS
SPATC1CDC2713199115280373 Affinity Capture-Western
SPATC1CDC2710743115280373 Affinity Capture-Western
PTTG1CDC2711466316479161 Affinity Capture-Western
PTTG1CDC2710743116479161 Affinity Capture-Western
CTNNB1CDC2710788016510875 Reconstituted Complex
CTNNB1CDC2710743116510875 Reconstituted Complex
CDKN1ACDC2710743117679094 Affinity Capture-Western
CDKN1ACDC2710746017679094 Affinity Capture-Western
MDC1CDC2711501417827148 Affinity Capture-Western; Reconstituted Complex
MDC1CDC2710743117827148 Affinity Capture-Western; Reconstituted Complex
USP11CDC2711386619615732 Affinity Capture-MS
USP11CDC2710743119615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
CDC27rs221597 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:102685
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990706-2'