AutismKB 2.0

Annotation Details for MVP


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MVP ( LRP,VAULT1 )
Gene Full Name: major vault protein
Band: 16p11.2
Quick LinksEntrez ID:9961; OMIM: 605088; Uniprot ID:MVP_HUMAN; ENSEMBL ID: ENSG00000013364; HGNC ID: 7531
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005634IDA-nucleus15133037
GO:0005643IEA-nuclear pore-
GO:0005737IDA-cytoplasm16441665
GO:0005829IDA-cytosol-
GO:0005856IDA-cytoskeleton16441665
GO:0016020IDA-membrane19946888
GO:0030529IEA-intracellular ribonucleoprotein complex-
GO:0034774TAS-secretory granule lumen-
GO:0048471IDA-perinuclear region of cytoplasm16441665
GO:0070062IDA-extracellular exosome19056867
GO:1904813TAS-ficolin-1-rich granule lumen-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15133037
GO:0019901IPI-protein kinase binding16441665
GO:0019903IDA-protein phosphatase binding15133037
GO:0042802IPI-identical protein binding21988832
GO ID Evidence Qualifier GO_term References
GO:0015031IEA-protein transport-
GO:0023057IDA-negative regulation of signaling16441665
GO:0031953IDA-negative regulation of protein autophosphorylation16441665
GO:0038127IDA-ERBB signaling pathway15133037
GO:0043312TAS-neutrophil degranulation-
GO:0051028IEA-mRNA transport-
GO:0061099IDA-negative regulation of protein tyrosine kinase activity16441665
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MVPPARP411528610477748 11855821 Reconstituted Complex; Two-hybrid
MVPPARP410665310477748 11855821 Reconstituted Complex; Two-hybrid
MVPESR11152869628887 Affinity Capture-Western; Reconstituted Complex
MVPESR11084039628887 Affinity Capture-Western; Reconstituted Complex
MVPPTEN11528612177006 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MVPPTEN11170012177006 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1925638
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved