AutismKB 2.0

Annotation Details for MED13


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Basic Information Top
Gene Symbol:MED13 ( ARC250,DRIP250,HSPC221,KIAA0593,THRAP1,TRAP240 )
Gene Full Name: mediator complex subunit 13
Band: 17q23.2
Quick LinksEntrez ID:9969; OMIM: 603808; Uniprot ID:MED13_HUMAN; ENSEMBL ID: ENSG00000108510; HGNC ID: 22474
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10235267
GO:0005654TAS-nucleoplasm-
GO:0016020IDA-membrane19946888
GO:0016592IDA-mediator complex10198638
GO ID Evidence Qualifier GO_term References
GO:0001104IDA-RNA polymerase II transcription cofactor activity10198638
GO:0003712IDA-transcription cofactor activity12218053
GO:0003713IDA-transcription coactivator activity12037571
GO:0004872IDA-receptor activity12218053
GO:0030374NAS-ligand-dependent nuclear receptor transcription coactivator activity10235266
GO:0042809NAS-vitamin D receptor binding10235266
GO:0046966IDA-thyroid hormone receptor binding10198638
GO ID Evidence Qualifier GO_term References
GO:0006367IDA-transcription initiation from RNA polymerase II promoter12218053
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0030518IDA-intracellular steroid hormone receptor signaling pathway11867769
GO:0030521IDA-androgen receptor signaling pathway12218053
GO:0042632IEA-cholesterol homeostasis-
GO:0045893IDA-positive regulation of transcription, DNA-templated10198638
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter12037571
GO:0070328IEA-triglyceride homeostasis-
GO:1904168IEA-negative regulation of thyroid hormone receptor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MED13BRCA111529415208681 Affinity Capture-MS
MED13BRCA110714015208681 Affinity Capture-MS
MED13CDK811529410198638 11867769 Affinity Capture-MS; Affinity Capture-Western
MED13CDK810745810198638 11867769 Affinity Capture-MS; Affinity Capture-Western
MED13ESR111529411867769 Reconstituted Complex
MED13ESR110840311867769 Reconstituted Complex
MED13MED111146515989967 Affinity Capture-MS; Affinity Capture-Western
MED13MED111529415989967 Affinity Capture-MS; Affinity Capture-Western
MED13SREBF111259810235267 Co-purification
MED13SREBF111529410235267 Co-purification
MED13VDR11326410198638 Affinity Capture-MS
MED13VDR11529410198638 Affinity Capture-MS
MED13TRRAP11529418418385 Co-purification
MED13TRRAP11390018418385 Co-purification
MED13SUPT3H11529417967894 Affinity Capture-Western
MED13SUPT3H11404217967894 Affinity Capture-Western
MED13MED2611529415175163 Affinity Capture-MS
MED13MED2611483115175163 Affinity Capture-MS
MED19MED1312855315175163 Affinity Capture-MS
MED19MED1311529415175163 Affinity Capture-MS
MED9MED1312040315175163 Affinity Capture-MS
MED9MED1311529415175163 Affinity Capture-MS
MED10MED1311529415175163 15989967 Affinity Capture-MS; Affinity Capture-Western
MED10MED1312397415175163 15989967 Affinity Capture-MS; Affinity Capture-Western
MED29MED1311529415175163 15989967 Affinity Capture-MS; Reconstituted Complex
MED29MED1312073415175163 15989967 Affinity Capture-MS; Reconstituted Complex
MED28MED1312321915175163 15989967 Affinity Capture-MS; Reconstituted Complex
MED28MED1311529415175163 15989967 Affinity Capture-MS; Reconstituted Complex
MED30MED1311529415989967 Affinity Capture-Western
MED30MED1312470715989967 Affinity Capture-Western
MED18MED1312015615989967 Reconstituted Complex
MED18MED1311529415989967 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:3029632
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070627-13'