AutismKB 2.0

Annotation Detail for A1BG


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Basic Information Top
Gene Symbol:A1BG ( A1B,ABG,DKFZp686F0970,GAB,HYST2477 )
Gene Full Name: alpha-1-B glycoprotein
Band: 19q13.43
Quick LinksEntrez ID:1; OMIM: 138670; Uniprot ID:A1BG_HUMAN; ENSEMBL ID: ENSG00000121410; HGNC ID: 5
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of A1BG mRNAaffects expression 16483693
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of A1BG mRNAaffects cotreatment|decreases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in decreased expression of A1BG mRNAaffects cotreatment|decreases expression 18164116
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of A1BG mRNAincreases expression 15953391
C517826 tetrabrominated diphenyl ether 47 tetrabrominated diphenyl ether 47 results in decreased expression of A1BG mRNAdecreases expression 20056577
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.5517505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000236 Adenoma beta-Naphthoflavone 7.5019389873
MESH:D000236 Adenoma Diethylnitrosamine 7.5010737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.4419052882 17620307 17162532 19061943 16434500 18056438
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.9511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8615885639
MESH:D001321 Autistic Disorder tetrabrominated diphenyl ether 47 3.3519211157
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.8718978308 17978847 10672840 20084675 17055752 17173139 16830150 20935162 18788625 16779866 10737359 19519916 17162532 16288022 20512989 11831363 16698587 17138121 19335982 18506893 16878318 20007298 18665156 20524982 18785209 19822196 19919837 17428255 18056438 21159647 18494052 19171122 16681979 16328049 16540662 16502159 20101231 18393292 19394651 17761372 18691550 19208518 20432363 19539802 19418558 3084413 18971187 20214788 19383236 16935385 20514400 19052882 16807293 19701751 3581430 18210153 19107877 16569478 20727157
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.0917174075 7505956 2727394 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0119052882
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1311677210 17110522 17333356 15861022 17681005 16105132 16919318
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1319107877
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6312538720
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.7316302075
MESH:D005234 Fatty Liver Diethylnitrosamine 8.9620387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.9615345470
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2916569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7117937319
MESH:D007249 Inflammation Diethylnitrosamine 2.5318785209
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9918407596 20032147 18522880 19638242 18665156
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 5.1419389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 5.1418977376 19255062 19426721 15885732 20452335 2422723 20101389 19850985 18648771 20434301 15175105 2862719 19254457 21167192 18644402 20118626 19812893 19996281 19690152 20501860 19294768 19551842 18754104 18978307 12112319 21071580 21278145 21047994 20137499 20583210 20405173 19642983 12771043 19090486 9163691 19499222 19073162 19833225 20492335 19638242 10737359 16942905 19256749 19427195
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 6.8218164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.8218164116 18079962 18253720 18544905 18093689 19004024 18775883 19539802 19126423 18282651 9362446 17174075 19519916 16267830 19009564 16842330 17854601 17942915 21159647 3124819 2563599 18308698
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7620970405 20512841 21163286 6695378
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.689029167 3581430
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6520387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.7320387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5216540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0911578682
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.882563599
MESH:D011537 Pruritus Ethinyl Estradiol 3.8516919318 15861022
MESH:D013088 Spermatocele Ethinyl Estradiol 4.5516709447
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4815669648
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.257505956
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.7414692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9115869587 14671159
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018