AutismKB 2.0

Annotation Detail for BCL2L11


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:BCL2L11 ( BAM,BIM,BIM-alpha6,BIM-beta6,BIM-beta7,BOD,BimEL,BimL )
Gene Full Name: BCL2-like 11 (apoptosis facilitator)
Band: 2q13
Quick LinksEntrez ID:10018; OMIM: 603827; Uniprot ID:B2L11_HUMAN; ENSEMBL ID: ENSG00000153094; HGNC ID: 994
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Signalling by NGF
Apoptosis
Pathway IDPathway Name
200091FoxO family signaling
200118AP-1 transcription factor network
200103p75(NTR)-mediated signaling
Pathway IDPathway Name
P00006Apoptosis signaling pathway
Pathway IDPathway Name
500262Activation of BIM and translocation to mitochondria
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
1989Vaccinia
2225Gram-Negative bacterial infection
2239Lymphoma
Desease Name
CANCER
Chronic lymphocytic leukemia
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C003001 7-ketocholesterol 7-ketocholesterol affects the localization of BCL2L11 proteinaffects localization 15955068
C501332 ABT-737 ABT-737 inhibits the reaction [BCL2L11 protein binds to BCL2 protein]affects binding|decreases reaction 17097560
D000082 Acetaminophen Acetaminophen affects the expression of BCL2L11 mRNAaffects expression 17562736
C103303 alitretinoin alitretinoin results in increased expression of BCL2L11 proteinincreases expression 16340750
C103303 alitretinoin seocalcitol inhibits the reaction [alitretinoin results in increased expression of BCL2L11 protein]decreases reaction|increases expression 16340750
D000638 Amiodarone Amiodarone results in increased expression of BCL2L11 mRNAincreases expression 19774075
D000643 Ammonium Chloride Ammonium Chloride affects the expression of BCL2L11 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of BCL2L11 mRNAincreases expression 17530438
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in decreased expression of BCL2L11 mRNAdecreases expression 18687144
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of BCL2L11 mRNAincreases expression 15735009
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of BCL2L11 mRNAdecreases expression 20713471
C400082 bortezomib bortezomib results in increased expression of BCL2L11 proteinincreases expression 16024631
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of BCL2L11 mRNAincreases expression 17482686
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of BCL2L11 proteinincreases expression 17482686
D002251 Carbon Tetrachloride PLG protein affects the reaction [Carbon Tetrachloride results in increased expression of BCL2L11 protein]affects reaction|increases expression 17482686
D003474 Curcumin Curcumin results in increased expression of BCL2L11 mRNAincreases expression 17332930
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of BCL2L11 mRNAincreases expression 17654400
C014347 decitabine decitabine results in decreased methylation of BCL2L11 promoterdecreases methylation 19403302
C014347 decitabine decitabine results in increased expression of BCL2L11 mRNAincreases expression 19403302
C014347 decitabine decitabine results in increased expression of BCL2L11 proteinincreases expression 19403302
D003907 Dexamethasone Dexamethasone results in increased expression of BCL2L11 mRNAincreases expression 12782123
D004317 Doxorubicin BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]affects cotreatment|affects response to substance 17339365
D004317 Doxorubicin BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]affects cotreatment|affects response to substance 17339365
D004317 Doxorubicin BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]affects cotreatment|increases activity|increases cleavage|increases reaction 17339365
D004317 Doxorubicin BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]affects cotreatment|increases degradation|increases reaction 17339365
D004317 Doxorubicin BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]affects cotreatment|increases activity|increases cleavage|increases reaction 17339365
D004317 Doxorubicin BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]affects cotreatment|increases degradation|increases reaction 17339365
D004317 Doxorubicin Doxorubicin results in decreased expression of BCL2L11 proteindecreases expression 17339365
C065180 fluvastatin [zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNAaffects cotreatment|increases expression 16996129
D005492 Folic Acid Folic Acid affects the expression of BCL2L11 mRNAaffects expression 16361273
D005665 Furosemide Furosemide affects the expression of BCL2L11 mRNAaffects expression 17497460
C056507 gemcitabine gemcitabine results in increased expression of BCL2L11 mRNAincreases expression 17039268
C097613 imatinib BCL2L11 protein results in increased susceptibility to imatinibincreases response to substance 19403302
D007530 Isoflurane Isoflurane results in decreased expression of BCL2L11 mRNAdecreases expression 16978161
C005219 methyl cellosolve methyl cellosolve results in increased expression of BCL2L11 mRNAincreases expression 19643169
D008769 Methylnitronitrosoguanidine [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 proteinaffects cotreatment|decreases expression 16030430
D008769 Methylnitronitrosoguanidine S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]affects cotreatment|decreases expression|decreases reaction 16030430
C008493 methylselenic acid BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with methylselenic acid]affects cotreatment|affects response to substance 17339365
C008493 methylselenic acid BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased cleavage of and results in increased activity of CASP9 protein]affects cotreatment|increases activity|increases cleavage|increases reaction 17339365
C008493 methylselenic acid BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with methylselenic acid] results in increased degradation of PARP1 protein]affects cotreatment|increases degradation|increases reaction 17339365
C008493 methylselenic acid methylselenic acid results in increased expression of BCL2L11 proteinincreases expression 17339365
C008542 monodansylcadaverine monodansylcadaverine results in increased expression of BCL2L11 proteinincreases expression 16170020
D009151 Mustard Gas Mustard Gas results in increased expression of BCL2L11 mRNAincreases expression 18955075
D010634 Phenobarbital Phenobarbital results in decreased expression of BCL2L11 mRNAdecreases expression 19270015
C006253 pirinixic acid pirinixic acid results in increased expression of BCL2L11 mRNAincreases expression 12832660
C025299 polyphenols polyphenols results in decreased expression of BCL2L11 mRNAdecreases expression 16293270
C031280 pyrazole pyrazole results in increased expression of BCL2L11 mRNAincreases expression 17945193
D020849 Raloxifene Raloxifene results in increased expression of BCL2L11 mRNAincreases expression 19429434
C059514 resveratrol resveratrol results in increased expression of BCL2L11 proteinincreases expression 17636462
C065299 S-allylcysteine S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]affects cotreatment|decreases expression|decreases reaction 16030430
C093642 SB 203580 SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of BCL2L11 protein]decreases reaction|increases phosphorylation 16818494
C515055 S-(dimethylarsino)-glutathione BCL2L11 protein affects the susceptibility to S-(dimethylarsino)-glutathioneaffects response to substance 19417148
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of BCL2L11 mRNAincreases expression 19417148
D012643 Selenium BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]affects cotreatment|affects response to substance 17339365
D012643 Selenium BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]affects cotreatment|increases activity|increases cleavage|increases reaction 17339365
D012643 Selenium BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]affects cotreatment|increases degradation|increases reaction 17339365
D012643 Selenium Selenium results in increased expression of BCL2L11 proteinincreases expression 17339365
C078903 seocalcitol seocalcitol inhibits the reaction [alitretinoin results in increased expression of BCL2L11 protein]decreases reaction|increases expression 16340750
C017947 sodium arsenite sodium arsenite results in decreased expression of BCL2L11 mRNAdecreases expression 19822182
C017947 sodium arsenite BCL2L11 protein results in increased susceptibility to sodium arseniteincreases response to substance 16818494
C017947 sodium arsenite SB 203580 inhibits the reaction [sodium arsenite results in increased phosphorylation of BCL2L11 protein]decreases reaction|increases phosphorylation 16818494
C017947 sodium arsenite sodium arsenite promotes the reaction [MAPK14 protein results in increased phosphorylation of BCL2L11 protein]increases phosphorylation|increases reaction 16818494
C017947 sodium arsenite sodium arsenite results in increased phosphorylation of BCL2L11 proteinincreases phosphorylation 16818494
D012965 Sodium Chloride [Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 proteinaffects cotreatment|decreases expression 16030430
D012965 Sodium Chloride S-allylcysteine inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of BCL2L11 protein]affects cotreatment|decreases expression|decreases reaction 16030430
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of BCL2L11 mRNAincreases expression 15800033
C111237 vorinostat vorinostat results in increased expression of BCL2L11 proteinincreases expression 16144943
C088658 zoledronic acid [zoledronic acid co-treated with fluvastatin] results in increased expression of BCL2L11 mRNAaffects cotreatment|increases expression 16996129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 11.736499812 6474471 3652986
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.736195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.7315322242 14514962 11752688
MESH:D000015 Abnormalities, Multiple imatinib 4.8518322153
MESH:D000022 Abortion, Spontaneous imatinib 5.7518322153
MESH:D000138 Acidosis Ammonium Chloride 3.1118287403
MESH:D058186 Acute Kidney Injury Folic Acid 12.3116316344 16595132 17003819
MESH:D058186 Acute Kidney Injury resveratrol 12.3116538975
MESH:D058186 Acute Kidney Injury zoledronic acid 12.3119715164
MESH:D055371 Acute Lung Injury pirinixic acid 2.7018653653
MESH:D000210 Acute-Phase Reaction zoledronic acid 5.0320200999
MESH:D000230 Adenocarcinoma arsenic trioxide 6.3411798837 19825857
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.3420464547 20127859
MESH:D000230 Adenocarcinoma Doxorubicin 6.3417418594
MESH:D000236 Adenoma Benzo(a)pyrene 9.746695378
MESH:D000236 Adenoma Folic Acid 9.7416963246
MESH:D000236 Adenoma resveratrol 9.7415688382
MESH:D018248 Adenoma, Liver Cell Phenobarbital 14.6617620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.6616434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.6616835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2415276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4416712894 17306315
MESH:D000419 Albuminuria Doxorubicin 10.0221441931
MESH:D000419 Albuminuria Raloxifene 10.0217308373 17451421
MESH:D019973 Alcohol-Related Disorders Curcumin 4.6217887948
MESH:D000544 Alzheimer Disease Curcumin 8.4815590663
MESH:D000544 Alzheimer Disease Folic Acid 8.4817116317
MESH:D000544 Alzheimer Disease Raloxifene 8.4815800139
MESH:D000544 Alzheimer Disease resveratrol 8.4816162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.5611748828
MESH:D000748 Anemia, Macrocytic methyl cellosolve 5.883699323
MESH:D000799 Angioedema Acetaminophen 3.3810982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.6319183758
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.4120041841 18218290 18057881
MESH:D001169 Arthritis, Experimental Dexamethasone 6.7217659584
MESH:D001169 Arthritis, Experimental resveratrol 6.7217115116
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.6216807698
MESH:D053627 Asthenozoospermia methyl cellosolve 5.073987992
MESH:D001249 Asthma Mustard Gas 2.5610378619
MESH:D050197 Atherosclerosis 7-ketocholesterol 9.7016632123
MESH:D050197 Atherosclerosis Curcumin 9.7018704882
MESH:D050197 Atherosclerosis resveratrol 9.7016873680 17967414
MESH:D001281 Atrial Fibrillation Amiodarone 3.5618651412 19698954
MESH:D001284 Atrophy methyl cellosolve 4.763699323 2626667 6705890
MESH:D001321 Autistic Disorder Acetaminophen 2.1618445737
MESH:D001321 Autistic Disorder Folic Acid 2.1621388746
MESH:D001327 Autoimmune Diseases Curcumin 4.0519761891
MESH:D001768 Blister Mustard Gas 4.7019167455
MESH:D001778 Blood Coagulation Disorders Amiodarone 18.6319483382
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 18.6316206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 18.6319483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 18.6312125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4615746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2414601052
MESH:D001859 Bone Neoplasms imatinib 9.7215867366
MESH:D001859 Bone Neoplasms zoledronic acid 9.7215867366 16778634 16121404 19442620 11697798 17312309
MESH:D001862 Bone Resorption zoledronic acid 4.3016769263 18404659 15845617 8053405 11869084 18496637
MESH:D001930 Brain Injuries Raloxifene 4.0316580743
MESH:D002545 Brain Ischemia Curcumin 8.8216770732
MESH:D002545 Brain Ischemia resveratrol 8.8217600658
MESH:D001932 Brain Neoplasms Curcumin 12.7217596214
MESH:D001932 Brain Neoplasms Doxorubicin 12.7217150277
MESH:D001932 Brain Neoplasms monodansylcadaverine 12.7216170020
MESH:D001943 Breast Neoplasms alitretinoin 10.3116344269
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 10.3117474063 20146248
MESH:D001943 Breast Neoplasms Curcumin 10.3119250217 18593918 18462866 16243823
MESH:D001943 Breast Neoplasms decitabine 10.3118320071 19208741
MESH:D001943 Breast Neoplasms Doxorubicin 10.3118628466 15939500 17983394 19526202 18234424 16096432 16595493 16264153 15136595 18695136 15634643 11325840 15567936 16115903 15993339 16826403 18382427 15994142 17426702 17369602 15692762 15668708 16322301 16935488
MESH:D001943 Breast Neoplasms Folic Acid 10.3116777985
MESH:D001943 Breast Neoplasms gemcitabine 10.3118382427 17039268
MESH:D001943 Breast Neoplasms imatinib 10.3117614352
MESH:D001943 Breast Neoplasms Raloxifene 10.3117242785 17893378 17595753 15572757 15775269 17049068 16837676 17952589 16912660 17261762 17440819 15758505
MESH:D001943 Breast Neoplasms resveratrol 10.3117651959 16393696 17534123
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.3120435547
MESH:D001943 Breast Neoplasms vorinostat 10.3116144943
MESH:D001943 Breast Neoplasms zoledronic acid 10.3116096432 18695136
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 4.7015286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 4.5117687719 10378619
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9111589617
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3415673190 3786805 15721981 15700767 16227642 16192424 16011737 16050911 18705752 16097048 10355542 16124888
MESH:D002276 Carcinoid Tumor Doxorubicin 4.3516051944
MESH:D002277 Carcinoma Curcumin 7.0918593918
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.0916835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 12.693084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 12.6915073043 14691202 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 12.6918788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 12.6916234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 12.6917173139 1701930 20007298 20935162 6705139
MESH:D006528 Carcinoma, Hepatocellular resveratrol 12.6919321006 16227395
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 12.6916507464 15276417 17306315
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.1416675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bortezomib 8.2316052434
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 8.2318414057
MESH:D002289 Carcinoma, Non-Small-Cell Lung zoledronic acid 8.2319233551
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4119014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.2216201981 1485588
MESH:D002292 Carcinoma, Renal Cell zoledronic acid 6.2218507039
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7212490120
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 16.0920419170
MESH:D002294 Carcinoma, Squamous Cell Curcumin 16.0918462866
MESH:D002294 Carcinoma, Squamous Cell decitabine 16.0919215824
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 16.096189445
MESH:D002294 Carcinoma, Squamous Cell resveratrol 16.0916227395
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 16.0918572023
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 3.6817572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1118850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2317382496 17519947 16952015 16364871 16278810 17329180 17007740 16612575 15792986 17131338 16455267 15476868 16242529 16731534 15811867 17308081 15505089 16109756 17924179 17974986 16651473 18627295 16269455 17351982 17928571
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 5.4015710769 19225199
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 5.4016243910 17334414
MESH:D002318 Cardiovascular Diseases Folic Acid 10.4916755160
MESH:D002318 Cardiovascular Diseases Raloxifene 10.4915775269
MESH:D002318 Cardiovascular Diseases resveratrol 10.4915458977
MESH:D002341 Carotid Artery Thrombosis Amiodarone 4.6318974383
MESH:D002386 Cataract Acetaminophen 2.3110977129
MESH:D002471 Cell Transformation, Neoplastic Methylnitronitrosoguanidine 6.142727394
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.1419524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.814080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D002764 Cholecystitis methyl cellosolve 5.346499794
MESH:D002779 Cholestasis pirinixic acid 2.4919176532
MESH:D002971 Cleft Lip Folic Acid 3.7321254359
MESH:D002972 Cleft Palate Folic Acid 5.4121254359 8946559
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.4115668235 8697196 15340226 16354765 12621046
MESH:D003072 Cognition Disorders Raloxifene 4.1715800139
MESH:D003092 Colitis Curcumin 13.5416782535 16804969 18200517
MESH:D003092 Colitis resveratrol 13.5416474422
MESH:D003092 Colitis Selenium 13.5417936198
MESH:D003103 Coloboma Curcumin 4.1418809619
MESH:D003110 Colonic Neoplasms Curcumin 9.9919359593 16340194
MESH:D003110 Colonic Neoplasms decitabine 9.9917616700
MESH:D003110 Colonic Neoplasms Dexamethasone 9.9915824018
MESH:D003110 Colonic Neoplasms polyphenols 9.9916293270
MESH:D003110 Colonic Neoplasms resveratrol 9.9916338953
MESH:D015179 Colorectal Neoplasms arsenic trioxide 5.9020501625
MESH:D015179 Colorectal Neoplasms decitabine 5.9018981723
MESH:D015179 Colorectal Neoplasms Doxorubicin 5.9018259882 18802399
MESH:D015179 Colorectal Neoplasms Folic Acid 5.9016985020 17087956 17116713 16963246 17245555
MESH:D015179 Colorectal Neoplasms resveratrol 5.9016550006
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.1612530607 6499821
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.1617141729 14669216
MESH:D016510 Corneal Neovascularization Curcumin 4.4518497527
MESH:D003327 Coronary Disease fluvastatin 7.9116142594
MESH:D003327 Coronary Disease resveratrol 7.9116507316
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9810525206
MESH:D019465 Craniofacial Abnormalities Dexamethasone 4.9817728286
MESH:D019465 Craniofacial Abnormalities imatinib 4.9818322153
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9820055451 10048152 15322242
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6815213294
MESH:D003865 Depressive Disorder, Major Raloxifene 3.7817474826
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 2.9912438553
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2018249437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.4016873680
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.4818403477
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 6.4816886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.4817107852
MESH:D003928 Diabetic Nephropathies Curcumin 12.9618204486
MESH:D003928 Diabetic Nephropathies Raloxifene 12.9617451421 15920148 17308373
MESH:D003928 Diabetic Nephropathies resveratrol 12.9616286809
MESH:D003967 Diarrhea Dexamethasone 7.117237001
MESH:D003967 Diarrhea vorinostat 7.1120479100
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 22.8119370779 12958197 10774834 11421492 14550746 17906064 12540782 11834606 12153990 16177239 11529661 19085960 16393943 19923254 12392966 16081117 11739529 17522070 11743745 19739265 16485898 2444490 17562736 11287661 18071297 16227642 14725611 19164858 10663392 16109766 10915739 14986274 19416960 12594235 12705907 15968718 18713872 15619225 16781746 19420014 11461765
MESH:D056486 Drug-Induced Liver Injury Amiodarone 22.8115265979 18218290
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 22.8117522070 7120509 21278145 19336974 2869522 15998439 16227642 3786805 15027814 3732212 10092053 9327722 7179309 6623471 4309450 15968718 10915739 11566570 6884620 7440962 19085960 16177239
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 22.8117654400
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 22.8117416283
MESH:D056486 Drug-Induced Liver Injury polyphenols 22.8119370779
MESH:D056486 Drug-Induced Liver Injury pyrazole 22.8112499123
MESH:D056486 Drug-Induced Liver Injury Selenium 22.8115131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 22.8120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6319426721
MESH:D004362 Drug Toxicity Doxorubicin 6.9818602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 6.9811462148
MESH:D004381 Duodenal Ulcer Curcumin 3.6217351913
MESH:D004417 Dyspnea Furosemide 4.4816935035
MESH:D004421 Dystonia Phenobarbital 3.591851702
MESH:D004485 Eczema Dexamethasone 4.0312438553
MESH:D004487 Edema Dexamethasone 31.2219703484
MESH:D004487 Edema Furosemide 31.2211834646
MESH:D004487 Edema imatinib 31.2219703484
MESH:D004487 Edema Mustard Gas 31.2211428631 11428647 11402378 9260866
MESH:D004487 Edema pirinixic acid 31.2212083418
MESH:D004487 Edema Raloxifene 31.2215860553
MESH:D004487 Edema resveratrol 31.228985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 31.2212711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4418230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 7.9915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 7.9917872969
MESH:D004701 Endocrine Gland Neoplasms decitabine 4.6519294695
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.9117359293
MESH:D016889 Endometrial Neoplasms Folic Acid 6.9117301261
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.639294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6918037988
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.4017923197
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.4111558140 3922381
MESH:D004827 Epilepsy Phenobarbital 2.6520417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.166401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.573659116
MESH:D004890 Erythema Mustard Gas 4.709357497
MESH:D004938 Esophageal Neoplasms arsenic trioxide 3.9812903497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 3.9816530937
MESH:D017889 Exfoliation Syndrome Folic Acid 5.0416504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.6711564622
MESH:D005221 Fatigue vorinostat 5.1420479100
MESH:D005234 Fatty Liver Amiodarone 25.4714986274
MESH:D005234 Fatty Liver arsenic trioxide 25.4715073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 25.4712795759 15959796 12631006 16045604 19224547 16239168 61145 17595544
MESH:D005234 Fatty Liver Curcumin 25.4719297423
MESH:D005234 Fatty Liver pirinixic acid 25.4719236843 20131406
MESH:D005234 Fatty Liver Raloxifene 25.4717473493
MESH:D005264 Femoral Fractures zoledronic acid 5.3716234978
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0111858732
MESH:D005327 Fetal Resorption methyl cellosolve 5.086474471 3987992 6499821 6499812
MESH:D020567 Fetal Weight methyl cellosolve 5.346499821 6474471 6499812
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.4719069698
MESH:D018222 Fibromatosis, Aggressive imatinib 10.4717453242
MESH:D005355 Fibrosis Carbon Tetrachloride 12.2618705752
MESH:D005355 Fibrosis Curcumin 12.2618705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.2620067830
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.053652986
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8316904648
MESH:D005756 Gastritis Acetaminophen 9.7316983495
MESH:D005756 Gastritis Folic Acid 9.7317171786
MESH:D005770 Gastrointestinal Neoplasms Curcumin 4.2518462866
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.2216452187
MESH:D005901 Glaucoma Folic Acid 4.6616504073
MESH:D005909 Glioblastoma Curcumin 10.5217596214
MESH:D005909 Glioblastoma Doxorubicin 10.5217150277
MESH:D005909 Glioblastoma monodansylcadaverine 10.5216170020
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1310696789
MESH:D006258 Head and Neck Neoplasms Curcumin 11.2518829502 18462866
MESH:D006258 Head and Neck Neoplasms decitabine 11.2519215824
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.2515692506
MESH:D034381 Hearing Loss Furosemide 4.4517868369
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 9.7420471113
MESH:D006330 Heart Defects, Congenital Folic Acid 9.7417286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 9.7411294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 6.7814766674 18006777 16244372 16495754 16879835 17875725 16707910 16144979 18674790 12587719 16330681 17888722 16244371
MESH:D006331 Heart Diseases Raloxifene 6.7811110106
MESH:D006333 Heart Failure Doxorubicin 14.5417481944
MESH:D006333 Heart Failure Furosemide 14.5416845234 12660669 16011733
MESH:D006333 Heart Failure pirinixic acid 14.5420558911
MESH:D006333 Heart Failure Selenium 14.5417162251
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.326499821
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5015692506
MESH:D006461 Hemolysis methyl cellosolve 4.9917874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9311000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.1719900420 19110552
MESH:D006529 Hepatomegaly Amiodarone 17.0415265979
MESH:D006529 Hepatomegaly Phenobarbital 17.0416109766
MESH:D006529 Hepatomegaly pirinixic acid 17.0418467677 19176532 16221962 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 17.0415340226 12621046 16120746
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.6017701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 2.907520565
MESH:D006561 Herpes Simplex resveratrol 3.7316876885
MESH:D006679 HIV Seropositivity Folic Acid 5.0417209195
MESH:D006689 Hodgkin Disease Doxorubicin 6.2317606976 18501091 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.2312676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5816354765 16959395 15340226 18606429 8697196
MESH:D006930 Hyperalgesia Acetaminophen 6.8216870215
MESH:D006930 Hyperalgesia zoledronic acid 6.8216769263
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.0816899240
MESH:D006934 Hypercalcemia bortezomib 16.0318089816
MESH:D006934 Hypercalcemia Furosemide 16.0317652376
MESH:D006934 Hypercalcemia zoledronic acid 16.0318089816 19622757
MESH:D053565 Hypercalciuria Furosemide 5.2017652376
MESH:D006937 Hypercholesterolemia Amiodarone 13.068137927 9751232
MESH:D006937 Hypercholesterolemia Curcumin 13.0618704882
MESH:D006937 Hypercholesterolemia resveratrol 13.0617188708
MESH:D006943 Hyperglycemia pirinixic acid 2.7920558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.1116865747 16433478 16395265 16755160 16397167
MESH:D006949 Hyperlipidemias resveratrol 3.6116873680
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.4115086907
MESH:D006973 Hypertension Dexamethasone 10.9017042910
MESH:D006973 Hypertension Raloxifene 10.9017577099 15787275
MESH:D006973 Hypertension Sodium Chloride 10.9011507004
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 10.9018850075 18670907
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6415338365
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 4.8416612254
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 3.9117488730
MESH:D006996 Hypocalcemia zoledronic acid 5.7312669777
MESH:C537153 Hypomagnesemia primary Furosemide 5.2011041285
MESH:D007019 Hypoproteinemia Furosemide 5.4116096441
MESH:D007022 Hypotension Furosemide 8.4811041285
MESH:D007022 Hypotension Isoflurane 8.4812967683
MESH:D007024 Hypotension, Orthostatic Furosemide 4.9515811171
MESH:D007037 Hypothyroidism Amiodarone 4.0717991464 18020914
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 4.2017600658
MESH:D007248 Infertility, Male decitabine 9.6517581917
MESH:D007248 Infertility, Male methyl cellosolve 9.653987992
MESH:D007248 Infertility, Male sodium arsenite 9.6512646999 15346721
MESH:D007249 Inflammation Curcumin 16.7216956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 16.728960868 11099482
MESH:D007249 Inflammation Mustard Gas 16.729357497 8975870 17524151 11402378 16001271 11428620 11428647 11428631 9260866
MESH:D007249 Inflammation polyphenols 16.7216366677
MESH:D007249 Inflammation resveratrol 16.7216366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 16.7212878042 12200463
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.0118596194 18200517
MESH:D007251 Influenza, Human resveratrol 9.5416624496
MESH:D007251 Influenza, Human Selenium 9.5416624496
MESH:D007333 Insulin Resistance pirinixic acid 2.3316306350
MESH:D007414 Intestinal Neoplasms Curcumin 3.8310783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9316580747
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.1816144296
MESH:D007674 Kidney Diseases Acetaminophen 12.2612587719 15629191
MESH:D007674 Kidney Diseases Doxorubicin 12.2615369732 15699352 16775033
MESH:D007674 Kidney Diseases Furosemide 12.2611041285
MESH:D007674 Kidney Diseases sodium arsenite 12.2620008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.6316707910
MESH:D007676 Kidney Failure, Chronic Selenium 8.6316518626
MESH:D007889 Leiomyoma Curcumin 9.7618555241
MESH:D007889 Leiomyoma Raloxifene 9.7616973256
MESH:D016773 Leishmaniasis, Cutaneous Sodium Chloride 4.569499605
MESH:D007938 Leukemia arsenic trioxide 9.1715070760
MESH:D007938 Leukemia Curcumin 9.1718462866
MESH:D007938 Leukemia decitabine 9.1718980019 19235587
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6916085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 19.9012560223 17077332
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell bortezomib 19.9018089816
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 19.9016106398
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell zoledronic acid 19.9018089816
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.8516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 7.7414633726
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive imatinib 7.7419208803 17301526 15107311 15748426
MESH:D007951 Leukemia, Myeloid arsenic trioxide 13.8419077051
MESH:D007951 Leukemia, Myeloid decitabine 13.8417236224 19117987 18454857
MESH:D007951 Leukemia, Myeloid imatinib 13.8417236224
MESH:D015470 Leukemia, Myeloid, Acute ABT-737 8.0917097560
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 8.0917050201 16467208 20471514 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute bortezomib 8.0920471514
MESH:D015470 Leukemia, Myeloid, Acute decitabine 8.0918460780 18206229 17679729 19010910 18704418 19387464
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.0018055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 6.7815622746 16331271 19075265 17869043 17649720 15748426 17712046 12679006 11468182 16966277 12018890 19225113 16112521 16330433 19642359 11161223 9834237 15336539 16823087 17217047 19035177 15213294 12712474 16891316 17107899
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 6.7816087638
MESH:D015458 Leukemia, T-Cell arsenic trioxide 10.2816882451
MESH:D015458 Leukemia, T-Cell Curcumin 10.2816106398
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 4.176499821
MESH:D008064 Lipidoses Amiodarone 3.1815342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.7616943688 21278145 11903743 17334410 17157831 16239168 16221502 11408273 17174718
MESH:D008103 Liver Cirrhosis Phenobarbital 5.7621047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 9.8315925388 16638106 18054572 14748882 18412020 18705752 18395914 17481882 12445418 18481824 12898905 14724832 18376398 15996030 18251166 18317297 16015684 12609069 17714472 18277467 12546737 18263696 15818738 15893842 14716496 15052691 17823541 12958196 12666154 18472094 15370692 15931870 14512876 18472332 17698563 12586293 12389079 16097048 17557913 15057751 18006644 12741479 14620537 17944888 17761835 16116963 16248980 17631135 17805973 11481614 15673190 12632512 18187930 15650968 15123356 18395095 18210741 18166357 12445421 17869086 17640975 16136751 17766677 20821823 17721639 15959796 18205269 16011737 18429990 14716833 15362042 18420326 15876570 12649538 12667390 17976157 16027843 17922224 18339082 17565644 17708605 17900296 12632514 16033810 18279442 16192424 10355542 18418968 15338365 18156304 15730626 13678700 17525996
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 9.8318705752 18006644 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 9.8316718785
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 9.8316439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental imatinib 9.8316596278
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 9.8315474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 9.8312878042
MESH:D008107 Liver Diseases Acetaminophen 14.0612587719 16611625 11587558 19784758 19460945 12969438 16610002 19014921
MESH:D008107 Liver Diseases Carbon Tetrachloride 14.0617285989 15720792 16964402 16246199 15830285
MESH:D008107 Liver Diseases Curcumin 14.0616956363
MESH:D008107 Liver Diseases Folic Acid 14.0616877991
MESH:D008107 Liver Diseases Phenobarbital 14.0619363144
MESH:D008107 Liver Diseases polyphenols 14.0616698588
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.1016871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.1014706259 16899240
MESH:D008113 Liver Neoplasms arsenic trioxide 22.5814682389
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 22.5821137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 22.5819294768
MESH:D008113 Liver Neoplasms Phenobarbital 22.5819482888 8742319 21047994 15975961 19812893 19073162
MESH:D008113 Liver Neoplasms pirinixic acid 22.5820007298 16377806 15890375
MESH:D008113 Liver Neoplasms resveratrol 22.5819812893 19073162 20405173 19321006
MESH:D008113 Liver Neoplasms sodium arsenite 22.5815276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 22.5816984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 15.5520377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 15.5512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 15.5517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 15.5518308698 1399818 17172636 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 15.5512151625
MESH:D008133 Long QT Syndrome Amiodarone 7.0415350150 11989578 17391786
MESH:D008133 Long QT Syndrome arsenic trioxide 7.0415213294
MESH:D008171 Lung Diseases Amiodarone 10.6012587719
MESH:D008171 Lung Diseases Mustard Gas 10.6018161513 18702808
MESH:D008171 Lung Diseases sodium arsenite 10.6019095001
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.0218516814
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.5917365036
MESH:D008175 Lung Neoplasms alitretinoin 14.0016413115
MESH:D008175 Lung Neoplasms arsenic trioxide 14.0011798837 19825857
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 14.0018816296 17053015 20135361 20464547 18569708 18520028 6695378 20064080 20869020
MESH:D008175 Lung Neoplasms Curcumin 14.0018462866 19359593 16243823
MESH:D008175 Lung Neoplasms Dexamethasone 14.0015824018 11195469
MESH:D008175 Lung Neoplasms Doxorubicin 14.0017418594 6189445
MESH:D008175 Lung Neoplasms Mustard Gas 14.008781369 3148597
MESH:D008175 Lung Neoplasms sodium arsenite 14.0017306315 16712894 15276417 17077188 19931552
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 14.0019555203 11884234
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.2017718048
MESH:D008223 Lymphoma bortezomib 15.2816098063
MESH:D008223 Lymphoma Curcumin 15.2818462866
MESH:D008223 Lymphoma decitabine 15.2819470736
MESH:D008223 Lymphoma Doxorubicin 15.2816098063
MESH:D016393 Lymphoma, B-Cell bortezomib 9.3516675587
MESH:D016393 Lymphoma, B-Cell resveratrol 9.3517088997
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.6517654614
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 7.6514749477
MESH:D016399 Lymphoma, T-Cell Curcumin 10.0916173963
MESH:D016399 Lymphoma, T-Cell Doxorubicin 10.0915621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 5.2420479100
MESH:D008231 Lymphopenia methyl cellosolve 5.323699323
MESH:D015674 Mammary Neoplasms, Animal resveratrol 3.8015688416
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 11.9015458769
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 11.9011606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Selenium 11.9015318939
MESH:D008325 Mammary Neoplasms, Experimental zoledronic acid 11.9017312309
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.2416832597
MESH:D008527 Medulloblastoma bortezomib 4.0319213072
MESH:D008545 Melanoma Curcumin 8.7517885582 18462866
MESH:D008545 Melanoma decitabine 8.7517785578 16505122
MESH:D008545 Melanoma Doxorubicin 8.7516827129
MESH:D008545 Melanoma resveratrol 8.7517992120
MESH:D008545 Melanoma sodium arsenite 8.7519082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1219513568
MESH:D008569 Memory Disorders Curcumin 3.7317263510
MESH:D008654 Mesothelioma Asbestos, Crocidolite 12.9516166281 16966607 18303189
MESH:D008654 Mesothelioma Doxorubicin 12.9517638057
MESH:D008654 Mesothelioma Selenium 12.9515107826
MESH:D008654 Mesothelioma zoledronic acid 12.9516675582
MESH:D008659 Metabolic Diseases resveratrol 3.9717112576
MESH:D053842 Microsatellite Instability Methylnitronitrosoguanidine 5.4317671175
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0915792986
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 5.0915863610
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 2.8416381670
MESH:D052016 Mucositis Doxorubicin 4.3417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 45.0715949261 11468182 19417148 19549372 14977855
MESH:D009101 Multiple Myeloma bortezomib 45.0719112201 19112817 19372569
MESH:D009101 Multiple Myeloma Curcumin 45.0719372569
MESH:D009101 Multiple Myeloma decitabine 45.0718172295
MESH:D009101 Multiple Myeloma Dexamethasone 45.0715744524 15867202 16118317
MESH:D009101 Multiple Myeloma fluvastatin 45.0716996129
MESH:D009101 Multiple Myeloma Raloxifene 45.0716497877
MESH:D009101 Multiple Myeloma resveratrol 45.0716490592 17164350 16267019 17049120 17935668 14749477
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 45.0719417148
MESH:D009101 Multiple Myeloma zoledronic acid 45.0718089719 16996129 19621390
MESH:D009134 Muscular Atrophy, Spinal Curcumin 10.9017962980
MESH:D009134 Muscular Atrophy, Spinal resveratrol 10.9017962980
MESH:D009135 Muscular Diseases pirinixic acid 3.0616239165
MESH:D009181 Mycoses Amiodarone 4.4417974566 12754197
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 10.8316105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 10.8319157545 16882708 19010910 18608210
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 10.839809623
MESH:D009203 Myocardial Infarction Doxorubicin 8.3119429709 15857846
MESH:D009203 Myocardial Infarction pirinixic acid 8.3119151258
MESH:D009203 Myocardial Infarction resveratrol 8.3117188708 17125593 16525036 17015251 16317513 16456233
MESH:D017202 Myocardial Ischemia resveratrol 7.8117125593 17015251
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 7.8112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.6016411023
MESH:D009205 Myocarditis resveratrol 4.3017322642
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0217484760
MESH:D009232 Myxoma Raloxifene 5.0916343187
MESH:D009325 Nausea vorinostat 5.0620479100
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 8.8916624393
MESH:D009361 Neoplasm Invasiveness Curcumin 8.8918495463
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.7118259882
MESH:D009362 Neoplasm Metastasis imatinib 8.7115867366
MESH:D009362 Neoplasm Metastasis zoledronic acid 8.7117312309 15867366 19139120
MESH:D009369 Neoplasms alitretinoin 13.1816946489
MESH:D009369 Neoplasms Benzo(a)pyrene 13.1811141357
MESH:D009369 Neoplasms decitabine 13.1817925555 19116145 19470736
MESH:D009369 Neoplasms pirinixic acid 13.1817405874
MESH:D009369 Neoplasms sodium arsenite 13.1811559025
MESH:D009374 Neoplasms, Experimental resveratrol 7.768985016
MESH:D009374 Neoplasms, Experimental sodium arsenite 7.7620056578
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 9.8412497104
MESH:D009376 Neoplasms, Hormone-Dependent imatinib 9.8417614352
MESH:D009397 Nephrocalcinosis Furosemide 5.4115086907
MESH:D009401 Nephrosis Doxorubicin 4.3216899518 16636307
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.6216889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.7814600291
MESH:D009423 Nervous System Neoplasms Curcumin 5.1718462866
MESH:D009436 Neural Tube Defects arsenic trioxide 10.5210525206
MESH:D009436 Neural Tube Defects Folic Acid 10.5217438019
MESH:D009436 Neural Tube Defects sodium arsenite 10.5212854658
MESH:D009447 Neuroblastoma Doxorubicin 3.0215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.1218514411
MESH:D019636 Neurodegenerative Diseases resveratrol 7.1217652729
MESH:D020078 Neurogenic Inflammation resveratrol 3.9817929310
MESH:D009503 Neutropenia Folic Acid 8.2116322990
MESH:D009503 Neutropenia Mustard Gas 8.217688884 16761898
MESH:D053206 Nocturnal Enuresis Furosemide 5.4117945291
MESH:D009765 Obesity Curcumin 4.1619297423
MESH:D009765 Obesity pirinixic acid 4.1620558911
MESH:D009845 Oligospermia methyl cellosolve 4.733987992
MESH:D010014 Osteolysis imatinib 11.0515867366
MESH:D010014 Osteolysis zoledronic acid 11.0515867366
MESH:D010018 Osteomalacia Phenobarbital 3.9117016548
MESH:D010024 Osteoporosis Curcumin 10.3918719352
MESH:D010024 Osteoporosis Raloxifene 10.3917882678 19059307 15775268
MESH:D010024 Osteoporosis zoledronic acid 10.3917882678
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 8.8115758505 17823083 17893378 15579764
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 8.8117513867
MESH:D012516 Osteosarcoma Doxorubicin 3.7515930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 9.9819769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Curcumin 9.9819020741 18462866
MESH:D010051 Ovarian Neoplasms decitabine 9.9819259094 19331143
MESH:D010051 Ovarian Neoplasms sodium arsenite 9.9815276417 17306315
MESH:D010146 Pain Acetaminophen 5.7616870215
MESH:D010146 Pain zoledronic acid 5.7616475674
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 14.4015580305
MESH:D010190 Pancreatic Neoplasms Curcumin 14.4019196508 17440100 19401701
MESH:D010190 Pancreatic Neoplasms decitabine 14.4019294695
MESH:D010190 Pancreatic Neoplasms gemcitabine 14.4016929163 18383843 18992248 17440100 11504793
MESH:D010190 Pancreatic Neoplasms Phenobarbital 14.4016965848
MESH:D010235 Paraganglioma arsenic trioxide 3.7419927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7812520081
MESH:D010538 Peritonitis Isoflurane 4.7817414419
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6917983394
MESH:D010954 Plasmacytoma Selenium 4.4215087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.4510923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.6917638057
MESH:D011041 Poisoning Mustard Gas 3.3815727166
MESH:D011141 Polyuria Furosemide 5.2017945291
MESH:D017499 Porokeratosis alitretinoin 5.5416144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1318163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.242563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 7.1821297632
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma imatinib 7.1812476293
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 13.8012530607 7974496 6499817
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 13.8016679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 13.8011399792 11222880 11896295 11118676
MESH:D055728 Primary Myelofibrosis decitabine 4.2817616702
MESH:C536419 Primary sclerosing cholangitis marker/mechanism 21151127
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.9519131511
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.9517292933
MESH:D011471 Prostatic Neoplasms Curcumin 3.9510851300 11398177 15129424 18156803 12497104 18226269 18769126
MESH:D011471 Prostatic Neoplasms Doxorubicin 3.9515749863 15897917 16888761 16868541 16729912 18437689
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.9516205645
MESH:D011471 Prostatic Neoplasms Raloxifene 3.9516536755 15731164 16220300
MESH:D011471 Prostatic Neoplasms resveratrol 3.9517636462 17675339 17804756 17718901 16731767 15767336
MESH:D011471 Prostatic Neoplasms S-allylcysteine 3.9517155983
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.9516039940
MESH:D011471 Prostatic Neoplasms vorinostat 3.9517218635
MESH:D011471 Prostatic Neoplasms zoledronic acid 3.9519103299 12438248
MESH:D011537 Pruritus Mustard Gas 3.6418058305
MESH:D019310 Pseudolymphoma Phenobarbital 4.0312752131
MESH:D011656 Pulmonary Emphysema Curcumin 4.1319168576
MESH:D011658 Pulmonary Fibrosis Amiodarone 11.7511597910 12832656 12490602
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 11.7515814490 17322281 17365031 17975199
MESH:D011658 Pulmonary Fibrosis Mustard Gas 11.7517894541 17720292 17620002 17266442 10334151
MESH:D011658 Pulmonary Fibrosis S-allylcysteine 11.7516614485
MESH:D011693 Purpura Raloxifene 5.0915770314
MESH:D051437 Renal Insufficiency Doxorubicin 9.0417922066
MESH:D051437 Renal Insufficiency Folic Acid 9.0415728788
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.1216325855
MESH:D015427 Reperfusion Injury Furosemide 9.6816526316
MESH:D015427 Reperfusion Injury pirinixic acid 9.6819058328
MESH:D015427 Reperfusion Injury resveratrol 9.6817520802 16314181 15827377 16317513 17058453
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 12.9410666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 12.9411700416 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 12.9416096441 15912074 12394941
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4118990726
MESH:D012208 Rhabdomyosarcoma decitabine 3.9819155313
MESH:D012509 Sarcoma Curcumin 8.2618462866
MESH:D012509 Sarcoma Doxorubicin 8.2615625365 18313854 17710206 15675481 16767912 17203757
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 14.8616646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 14.8616326096 14601052
MESH:D012512 Sarcoma, Ewing's zoledronic acid 14.8616121404
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3417846226
MESH:D012559 Schizophrenia Folic Acid 2.8316641680
MESH:D012640 Seizures Phenobarbital 2.404039156 3137016 11442880 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.376407741
MESH:D018805 Sepsis Curcumin 8.5818389075
MESH:D018805 Sepsis Isoflurane 8.5817414419
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 4.6318724381
MESH:D012871 Skin Diseases Folic Acid 4.8718709164
MESH:D012871 Skin Diseases Mustard Gas 4.8715451306 12880345 16961503
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 15.4819755658 10029692
MESH:D012878 Skin Neoplasms Doxorubicin 15.4815692506
MESH:D012878 Skin Neoplasms resveratrol 15.4815837718 8985016
MESH:D012878 Skin Neoplasms sodium arsenite 15.4819524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 15.4816192470
MESH:D055752 Small Cell Lung Carcinoma ABT-737 6.6619010845
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1215625365 17203757 16767912
MESH:D013118 Spinal Cord Diseases Folic Acid 5.0416361298
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4412854658
MESH:D013272 Stomach Diseases Dexamethasone 3.8715472012
MESH:D013274 Stomach Neoplasms arsenic trioxide 9.4917007042
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 9.492093021 20155912
MESH:D013274 Stomach Neoplasms decitabine 9.4919037991
MESH:D013274 Stomach Neoplasms Folic Acid 9.4917171786
MESH:D013274 Stomach Neoplasms Furosemide 9.4917052386
MESH:D013274 Stomach Neoplasms imatinib 9.4915786421
MESH:D013274 Stomach Neoplasms Sodium Chloride 9.4916646055
MESH:D013276 Stomach Ulcer Amiodarone 9.8418087811
MESH:D013276 Stomach Ulcer Curcumin 9.8419188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 9.8415138204
MESH:D020521 Stroke Folic Acid 7.8116517955
MESH:D020521 Stroke Raloxifene 7.8116837676
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.0816321402
MESH:D013610 Tachycardia Amiodarone 3.8611238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 3.7619225199
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.7917997062
MESH:D013733 Testicular Diseases methyl cellosolve 9.406499806
MESH:D013733 Testicular Diseases pyrazole 9.406499806
MESH:D013921 Thrombocytopenia vorinostat 4.5820479100
MESH:D013959 Thyroid Diseases Amiodarone 10.5119731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 10.5112697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.8319014326
MESH:D013964 Thyroid Neoplasms decitabine 18.8317967635
MESH:D013964 Thyroid Neoplasms Doxorubicin 18.8316010429 17909728
MESH:D013964 Thyroid Neoplasms imatinib 18.8316940797
MESH:D013964 Thyroid Neoplasms Phenobarbital 18.831399818
MESH:D013971 Thyrotoxicosis Amiodarone 4.4218020914 19584973
MESH:D013978 Tibial Fractures Raloxifene 4.7419048282
MESH:D014062 Tongue Neoplasms resveratrol 3.8216227395
MESH:D016171 Torsades de Pointes Amiodarone 8.7511989578 17467628
MESH:D016171 Torsades de Pointes arsenic trioxide 8.7515213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 21.1212845720 20435036 12973940 11780464
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 21.1217053015
MESH:D001749 Urinary Bladder Neoplasms Curcumin 21.1218593936
MESH:D001749 Urinary Bladder Neoplasms decitabine 21.1217616700 19087683
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 21.1217653716
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 21.1217572228
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 21.1211723127 16452187 17306315 16712894
MESH:D014565 Urogenital Neoplasms Curcumin 4.8118462866
MESH:D014581 Urticaria Acetaminophen 2.5610982225
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.2617473185
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.2611813266
MESH:D014594 Uterine Neoplasms resveratrol 3.7117044934
MESH:D014604 Uveal Neoplasms decitabine 4.4517785578
MESH:D014605 Uveitis Dexamethasone 4.351336536
MESH:D014652 Vascular Diseases sodium arsenite 3.9717056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1312125929
MESH:D054556 Venous Thromboembolism Raloxifene 4.7416837676
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 8.8717334414 16364871 17638931 17678736
MESH:D018487 Ventricular Dysfunction, Left resveratrol 8.8717488730
MESH:D014846 Vulvar Neoplasms Raloxifene 5.0916343187
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7815886252
Pathway ID Pathway Name
REACT:578 Apoptosis
REACT:11061 Signalling by NGF
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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