AutismKB 2.0

Annotation Detail for TROAP


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Basic Information Top
Gene Symbol:TROAP ( TASTIN )
Gene Full Name: trophinin associated protein (tastin)
Band: 12q13.12
Quick LinksEntrez ID:10024; OMIM: 603872; Uniprot ID:TROAP_HUMAN; ENSEMBL ID: ENSG00000135451; HGNC ID: 12327
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TROAP mRNAdecreases expression 20382639
D005472 Fluorouracil TP53 protein affects the reaction [Fluorouracil results in decreased expression of TROAP mRNA]affects reaction|decreases expression 15016801
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of TROAP mRNAincreases expression 20713471
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Fluorouracil 2.5017638652
MESH:D000236 Adenoma Methylcholanthrene 3.726695378 10545420
MESH:D000740 Anemia Fluorouracil 4.1615504547 16511603 17963324
MESH:D050197 Atherosclerosis Methylcholanthrene 3.6911922910
MESH:D001943 Breast Neoplasms Fluorouracil 2.4516595493 16557594 18608205 19217205 16110121 15136595 18357371
MESH:D001943 Breast Neoplasms Methylcholanthrene 2.4517474063
MESH:D002276 Carcinoid Tumor Fluorouracil 5.5316051944
MESH:D002277 Carcinoma Fluorouracil 9.8517121937
MESH:D002277 Carcinoma Methylcholanthrene 9.8510545420
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 2.1217088986 17045692 16332177 16799960 17971768 18930000
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1818695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5818986760 16757204 17066447 16280240
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.9020889678
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 7.9016192471
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2917169374 18772588 17018589 15001691 16340194 16510598 17287894 17725105 17016597 17172411
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0017255274 16282729 15289873 18802399 18509181 18448328 17016601 16524972 16303861 20501625 17094418 17695437 16331619 17594712 18383874 17454858 14970324 16391804 15148649 17401013 18949393 18288408
MESH:D007644 Darier Disease Fluorouracil 5.5316733453
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.8020426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.8016337965 16481741 16785472 17638652 15173087
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.6810962813 14633661
MESH:D005910 Glioma Fluorouracil 3.0016145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.6715102660 15162350 18337622
MESH:D007680 Kidney Neoplasms Fluorouracil 3.6916985049
MESH:D008113 Liver Neoplasms Fluorouracil 2.6117045692 18383874 16603448 15113037
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 3.521399818 598648
MESH:D008175 Lung Neoplasms Fluorouracil 2.8715246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 2.8716271038 21163286 20970405 20512841 1399818 6695378 15390079 9230183 10545420 16337739 7750092 11893704 17909032
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.5315086387
MESH:D009062 Mouth Neoplasms Fluorouracil 3.9816757204 18986760
MESH:D009369 Neoplasms Fluorouracil 2.7916928823 18239605 18600527
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.7216436463
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7816500647 16929163 19003803 15113037
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3419082440 18626508
MESH:D012004 Rectal Neoplasms Fluorouracil 4.4318286688 16160472 18722050 15538739
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0017498489 19015929 19084572 18396642 16424979 18567086 17522103 16951190 17172411 15786421
MESH:D014062 Tongue Neoplasms Fluorouracil 4.4416280240
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.3316803524
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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