Annotation Detail for TOM1L1
Basic Information Top
| Gene Symbol: | TOM1L1 ( OK/KNS-CL.3,SRCASM ) |
|---|---|
| Gene Full Name: | target of myb1 (chicken)-like 1 |
| Band: | 17q23.2 |
| Quick Links | Entrez ID:10040; OMIM: 604701; Uniprot ID:TM1L1_HUMAN; ENSEMBL ID: ENSG00000141198; HGNC ID: 11983 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000638 | Amiodarone | Amiodarone results in increased expression of TOM1L1 mRNA | increases expression | 19774075 |
| D002251 | Carbon Tetrachloride | Carbon Tetrachloride affects the expression of TOM1L1 mRNA | affects expression | 17484886 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 4.31 | 18057881 18218290 20041841 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 4.27 | 18651412 19698954 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 4.45 | 19483382 | |
| MESH:D002252 | Carbon Tetrachloride Poisoning | Carbon Tetrachloride | 4.54 | 15700767 3786805 16124888 16192424 15673190 10355542 15721981 16050911 16011737 18705752 16227642 16097048 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Carbon Tetrachloride | 1.86 | 18788625 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 3.02 | 19225199 15710769 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 5.97 | 18974383 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 4.40 | 15265979 18218290 | |
| MESH:D056486 | Drug-Induced Liver Injury | Carbon Tetrachloride | 4.40 | 17522070 15998439 21278145 6623471 7440962 19085960 15968718 16177239 7179309 7120509 10915739 19336974 15027814 3786805 2869522 3732212 6884620 11566570 10092053 16227642 9327722 4309450 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 9.84 | 14986274 | |
| MESH:D005234 | Fatty Liver | Carbon Tetrachloride | 9.84 | 16239168 12631006 61145 12795759 17595544 15959796 16045604 19224547 | |
| MESH:D005355 | Fibrosis | Carbon Tetrachloride | 4.22 | 18705752 | |
| MESH:D006505 | Hepatitis | Carbon Tetrachloride | 4.27 | 19900420 19110552 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 4.51 | 15265979 | |
| MESH:D006932 | Hyperbilirubinemia | Carbon Tetrachloride | 5.42 | 16899240 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 4.42 | 9751232 8137927 | |
| MESH:D006975 | Hypertension, Portal | Carbon Tetrachloride | 4.85 | 15338365 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 5.28 | 17991464 18020914 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.85 | 15342952 17567588 | |
| MESH:D008103 | Liver Cirrhosis | Carbon Tetrachloride | 3.04 | 16943688 11408273 11903743 17334410 17157831 17174718 21278145 16221502 16239168 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Carbon Tetrachloride | 1.76 | 17698563 17714472 15893842 18279442 15052691 18251166 17631135 12546737 12649538 17805973 16027843 15673190 15959796 18210741 17766677 15338365 18418968 18376398 12632512 15362042 17869086 17708605 16192424 12741479 17823541 17761835 18263696 18412020 14716833 17721639 14748882 15996030 18481824 15123356 14724832 18395914 14620537 16248980 12958196 12632514 16638106 17557913 18277467 18205269 18395095 15730626 12609069 10355542 18166357 18429990 14716496 12586293 15057751 12898905 18705752 18339082 16011737 15818738 15925388 13678700 20821823 17525996 18006644 12667390 17944888 15931870 18054572 17481882 16033810 18187930 18420326 17976157 12389079 14512876 17900296 12666154 16136751 17565644 12445418 18472332 16015684 16116963 15650968 16097048 12445421 18317297 15370692 18472094 18156304 15876570 17922224 11481614 17640975 | |
| MESH:D008107 | Liver Diseases | Carbon Tetrachloride | 2.17 | 16246199 17285989 15830285 15720792 16964402 | |
| MESH:D017093 | Liver Failure | Carbon Tetrachloride | 4.93 | 15123358 | |
| MESH:D017114 | Liver Failure, Acute | Carbon Tetrachloride | 4.20 | 16899240 14706259 | |
| MESH:D008113 | Liver Neoplasms | Carbon Tetrachloride | 2.36 | 19294768 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Carbon Tetrachloride | 2.89 | 15583823 12014681 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 3.96 | 11989578 17391786 15350150 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 3.68 | 12587719 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 5.55 | 18516814 | |
| MESH:D009181 | Mycoses | Amiodarone | 5.97 | 12754197 17974566 | |
| MESH:D011471 | Prostatic Neoplasms | marker/mechanism | 17013881 | ||
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.99 | 11597910 12832656 12490602 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 5.97 | 18724381 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 3.86 | 18087811 | |
| MESH:D013610 | Tachycardia | Amiodarone | 4.96 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 4.86 | 19225199 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 5.83 | 19731979 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 5.62 | 18020914 19584973 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 5.08 | 11989578 17467628 |
| No data |