AutismKB 2.0

Annotation Detail for TOM1


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Basic Information Top
Gene Symbol:TOM1 ( FLJ33404 )
Gene Full Name: target of myb1 (chicken)
Band: 22q12.3
Quick LinksEntrez ID:10043; OMIM: 604700; Uniprot ID:TOM1_HUMAN; ENSEMBL ID: ENSG00000100284; HGNC ID: 11982
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
200130C-MYB transcription factor network
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Related Diseases/Disorders Top
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Desease IDDesease Name
2221Behavior disease
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of TOM1 mRNAincreases expression 12414654
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of TOM1 mRNAaffects expression 17555576
D006861 Hydrogen Peroxide Hydrogen Peroxide results in increased expression of TOM1 mRNAincreases expression 12414654
D020849 Raloxifene Raloxifene affects the expression of TOM1 mRNAaffects expression 14699072
D013629 Tamoxifen Tamoxifen affects the expression of TOM1 mRNAaffects expression 17555576
D024483 Vitamin K 3 Vitamin K 3 results in increased expression of TOM1 mRNAincreases expression 12414654
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 5.0714745880
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.4617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8714692618
MESH:D000419 Albuminuria Raloxifene 4.9817308373 17451421
MESH:D000544 Alzheimer Disease Raloxifene 2.5915800139
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8415885639
MESH:D001930 Brain Injuries Raloxifene 4.8916580743
MESH:D001943 Breast Neoplasms Raloxifene 2.2816912660 17440819 17049068 17261762 17952589 17595753 17893378 15758505 17242785 15775269 15572757 16837676
MESH:D001943 Breast Neoplasms Tamoxifen 2.2819066611 19221464 17242785 20390343 20135344 19200415 19155303 19142967 20005174 19189212 18351453 15668708 11161223 20859285 20065188 19084267 19244106 18629630 18425577 19189210 19059307 21138602 19289846 19487384 18997820 17049068 18821012 16202921 16273361 21152245 18984771 15565566 16818667 19115204 19103187 17261762 19288272 19011961 17440819 18855134 20544844 19410462 17893378 18815881 16873071
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.9219066611
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 1.8516924424
MESH:D002295 Carcinoma, Transitional Cell Raloxifene 10.5317572228
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 10.5317572228
MESH:D002318 Cardiovascular Diseases Hydrogen Peroxide 8.2816936243
MESH:D002318 Cardiovascular Diseases Raloxifene 8.2815775269
MESH:D002779 Cholestasis Ethinyl Estradiol 3.1016919318 17333356 11677210 15861022 17681005 17110522 16105132
MESH:D003072 Cognition Disorders Raloxifene 5.0415800139
MESH:D003711 Demyelinating Diseases Tamoxifen 4.7819031437
MESH:D003865 Depressive Disorder, Major Raloxifene 4.4517474826
MESH:D003928 Diabetic Nephropathies Raloxifene 10.0015920148 17451421 17308373
MESH:D003928 Diabetic Nephropathies Tamoxifen 10.0019279558
MESH:D004487 Edema Raloxifene 3.6615860553
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 17.6912538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Raloxifene 17.6915845917
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 17.6919031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.2420544844 19155303 17893378 16202921
MESH:D005234 Fatty Liver Ethinyl Estradiol 15.1315345470
MESH:D005234 Fatty Liver Raloxifene 15.1317473493
MESH:D005234 Fatty Liver Tamoxifen 15.1314986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.4116709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.9914745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.6419069698
MESH:D006331 Heart Diseases Raloxifene 3.7411110106
MESH:D006973 Hypertension Raloxifene 2.9615787275 17577099
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2316945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6817937319
MESH:D007249 Inflammation Tamoxifen 2.4919457130
MESH:D007676 Kidney Failure, Chronic Hydrogen Peroxide 4.6016518626
MESH:D007680 Kidney Neoplasms Tamoxifen 3.3118625569
MESH:D007889 Leiomyoma Raloxifene 4.8516973256
MESH:D008064 Lipidoses Tamoxifen 3.3717567588 15342952
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 1.7518564211
MESH:D008113 Liver Neoplasms Tamoxifen 2.3116684651
MESH:D008175 Lung Neoplasms Tamoxifen 1.7418625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.2219428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.8114580682 19196723 11731420 19196722 16827153
MESH:D020149 Manganese Poisoning Tamoxifen 5.0719453300
MESH:D008545 Melanoma Tamoxifen 3.8812393984 19393235
MESH:D008545 Melanoma Vitamin K 3 3.8819082730
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.6415990972
MESH:D018200 Mixed Tumor, Mullerian Raloxifene 6.0815863610
MESH:D009101 Multiple Myeloma Raloxifene 3.6516497877
MESH:D009232 Myxoma Raloxifene 6.0816343187
MESH:D009362 Neoplasm Metastasis Tamoxifen 2.6519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.6019410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.5219196722 19189210 19200415
MESH:D010024 Osteoporosis Raloxifene 3.5719059307 17882678 15775268
MESH:D015663 Osteoporosis, Postmenopausal Raloxifene 4.5817823083 15579764 15758505 17893378
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0411578682
MESH:D010212 Papilloma Hydrogen Peroxide 4.5012065085
MESH:D011471 Prostatic Neoplasms Raloxifene 3.3016536755 16220300 15731164
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.3015067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.7716919318 15861022
MESH:D011693 Purpura Raloxifene 6.0815770314
MESH:D012878 Skin Neoplasms Hydrogen Peroxide 6.4012065085
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 6.408532709
MESH:D013088 Spermatocele Ethinyl Estradiol 13.3616709447
MESH:D013088 Spermatocele Tamoxifen 13.3616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.5019457130
MESH:D020521 Stroke Raloxifene 4.0816837676
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4415669648
MESH:D013978 Tibial Fractures Raloxifene 5.7319048282
MESH:D001749 Urinary Bladder Neoplasms Raloxifene 5.5717572228
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 5.578653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6814692618
MESH:D054556 Venous Thromboembolism Raloxifene 5.7316837676
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8715869587 14671159
MESH:D014846 Vulvar Neoplasms Raloxifene 6.0816343187
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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