AutismKB 2.0

Annotation Detail for RANBP9


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Basic Information Top
Gene Symbol:RANBP9 ( BPM-L,BPM90,RANBPM,RanBP7 )
Gene Full Name: RAN binding protein 9
Band: 6p23
Quick LinksEntrez ID:10048; OMIM: 603854; Uniprot ID:RANB9_HUMAN; ENSEMBL ID: ENSG00000010017; HGNC ID: 13727
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Axon guidance
Pathway IDPathway Name
200038Coregulation of Androgen receptor activity
200032Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
No data
Pathway IDPathway Name
500097L1CAM interactions
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of RANBP9 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of RANBP9 mRNAincreases expression 20458559
D016572 Cyclosporine Cyclosporine results in increased expression of RANBP9 mRNAincreases expression 20106945
C006253 pirinixic acid pirinixic acid results in increased expression of RANBP9 mRNAincreases expression 18301758
D012643 Selenium Selenium results in decreased expression of RANBP9 mRNAdecreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of RANBP9 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3419825857 11798837
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.9416434500
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 10.1016206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 10.1019483382
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6811589617
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.3516050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 3.013084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.0115553829 16217749 11135700 14691202 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4019014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4212490120
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7312371664
MESH:D002779 Cholestasis Cyclosporine 8.5319486331
MESH:D002779 Cholestasis pirinixic acid 8.5319176532
MESH:D003092 Colitis Selenium 4.2017936198
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.7810525206
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.7819769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4515213294
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0411739529 10915739 11743745 11421492 19164858 12705907 16781746 12594235 12540782 12392966 12153990 18071297 11529661 11461765 19739265 17906064 19923254 19416960 19420014 11834606 2444490 16227642 10663392 16177239 14725611 16081117 14550746 14986274 18713872 15968718 15619225 11287661 17562736 16393943 16109766 16485898 10774834 12958197 19370779 19085960 17522070
MESH:D056486 Drug-Induced Liver Injury Selenium 4.0415131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:C538011 Eales disease Vitamin E 5.229068938
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3712903497
MESH:D005234 Fatty Liver arsenic trioxide 15.0315073043
MESH:D005234 Fatty Liver Cyclosporine 15.0319224547
MESH:D005234 Fatty Liver pirinixic acid 15.0320131406 19236843
MESH:D005355 Fibrosis Cyclosporine 3.5612168785 12639820
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.6416904648
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1316080930
MESH:D006333 Heart Failure pirinixic acid 7.5520558911
MESH:D006333 Heart Failure Selenium 7.5517162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006529 Hepatomegaly pirinixic acid 3.4116221962 19772884 18467677 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7916863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.4914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007251 Influenza, Human Selenium 12.7616624496
MESH:D007251 Influenza, Human Vitamin E 12.7616624496
MESH:D007333 Insulin Resistance pirinixic acid 2.8216306350
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Acetaminophen 10.9715629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 10.978314463 10903974 18776723
MESH:D007674 Kidney Diseases Vitamin E 10.9712488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.2116518626
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D007938 Leukemia arsenic trioxide 2.9615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1820471514 16467208 16968895 19850784 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4111468182 17217047 15336539 19075265 19642359 17869043 17649720 12018890 19035177 11161223 16330433 15213294 17712046 19225113 17107899 12679006 15748426 15622746 16331271 16891316 9834237 16966277 12712474 16112521 16823087
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7316882451
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4515474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.4516169303
MESH:D008107 Liver Diseases Acetaminophen 1.6919784758 12587719 12969438 16611625 19014921 19460945 11587558 16610002
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5417185352 16871587
MESH:D008113 Liver Neoplasms arsenic trioxide 4.8114682389
MESH:D008113 Liver Neoplasms pirinixic acid 4.8116377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.9120377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5915213294
MESH:D008171 Lung Diseases Vitamin E 3.3716863852
MESH:D008175 Lung Neoplasms arsenic trioxide 2.6111798837 19825857
MESH:D008175 Lung Neoplasms Vitamin E 2.6111062179
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9515318939
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008654 Mesothelioma Selenium 2.8915107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3211468182 19417148 15949261 19549372 14977855
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3016105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.3416624393
MESH:D009369 Neoplasms pirinixic acid 2.0817405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5718481113 19348381
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3110525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity pirinixic acid 1.8720558911
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4812452020 16624393 19769630
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6115580305
MESH:D010235 Paraganglioma arsenic trioxide 4.5119927285
MESH:D010954 Plasmacytoma Selenium 5.4115087411
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2319131511
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2315084515
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.3416646077
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D020521 Stroke Vitamin E 3.7716517955
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3219014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.4215213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 2.5811780464 12845720 20435036 12973940
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
Pathway ID Pathway Name
REACT:18266 Axon guidance
Pharmacogenomics Knowledge Base Top
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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