AutismKB 2.0

Annotation Detail for CDH10


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Basic Information Top
Gene Symbol:CDH10 ( - )
Gene Full Name: cadherin 10, type 2 (T2-cadherin)
Band: 5p14.2-p14.1
Quick LinksEntrez ID:1008; OMIM: 604555; Uniprot ID:CAD10_HUMAN; ENSEMBL ID: ENSG00000040731; HGNC ID: 1749
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Cell junction organization
No data
Pathway IDPathway Name
P00012Cadherin signaling pathway
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
No data
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Desease Name
PSYCH
Autism
Desease Name
Autism
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CDH10 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CDH10 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of CDH10 mRNAincreases expression 20106945
D016572 Cyclosporine Cyclosporine results in increased expression of CDH10 mRNAincreases expression 20106945
D005419 Flavonoids Flavonoids results in increased expression of CDH10 mRNAincreases expression 18035473
D014415 Tunicamycin Tunicamycin results in increased expression of CDH10 mRNAincreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0420464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 2.826695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.4919183758
MESH:D001321 Autistic Disorder marker/mechanism 19404256
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9821507988 12907637 12619106
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1220419170
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7312371664
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Cyclosporine 3.1819224547
MESH:D005355 Fibrosis Cyclosporine 3.5612168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8020471113
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007249 Inflammation Flavonoids 2.7917296493
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.508314463 10903974 18776723
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.8918177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8920195826 21137059
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.928603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.4914755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4920464547 18520028 18816296 20135361 18569708 17053015 20869020 6695378 20064080
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4316381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3011141357
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5718481113 19348381
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9217292933
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.4919755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.5620155912 2093021
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2817053015
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
Pathway ID Pathway Name
REACT:20676 Cell junction organization
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26283
  • No data
    Releated disease ID Related disease Name
    PA445218Pancreatic Neoplasms
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018