AutismKB 2.0

Annotation Detail for FRY


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Basic Information Top
Gene Symbol:FRY ( 13CDNA73,214K23.2,C13orf14,CG003,bA207N4.2,bA37E23.1 )
Gene Full Name: furry homolog (Drosophila)
Band: 13q13.1
Quick LinksEntrez ID:10129; OMIM: NA; Uniprot ID:FRY_HUMAN; ENSEMBL ID: ENSG00000073910; HGNC ID: 20367
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FRY mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of FRY proteinaffects expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of FRY mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of FRY mRNAaffects expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of FRY mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of FRY mRNAaffects expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.2615700767 10355542 16227642 16097048 18705752 16124888 15673190 16011737 15721981 3786805 16192424 16050911
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.793084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.7921507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.7918788625
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9620889678
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0211743745 18713872 16485898 11461765 19370779 19416960 19164858 18071297 11739529 12153990 19923254 15619225 17562736 15968718 10663392 14725611 19420014 10915739 16393943 17522070 12540782 12705907 12392966 16109766 12594235 16081117 11529661 11834606 2444490 19085960 14550746 11287661 10774834 11421492 16177239 19739265 14986274 16227642 17906064 12958197 16781746
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 4.023732212 19085960 19336974 17522070 10092053 15968718 3786805 21278145 7179309 16227642 15027814 4309450 7120509 10915739 6884620 16177239 11566570 9327722 7440962 2869522 15998439 6623471
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.5920426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.5916530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.5412631006 16045604 15959796 61145 12795759 16239168 19224547 17595544
MESH:D005355 Fibrosis Carbon Tetrachloride 3.9418705752
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006505 Hepatitis Carbon Tetrachloride 4.0319110552 19900420
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.0716899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.5715338365
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9811408273 16221502 16943688 16239168 21278145 17174718 17334410 17157831 11903743
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7517640975 18472332 15876570 18054572 12445421 16136751 15730626 17761835 17805973 12389079 16248980 17698563 16027843 15925388 15338365 14620537 12632514 18006644 18429990 14716496 18210741 14748882 18156304 18277467 15673190 15370692 18263696 14512876 15959796 17823541 18279442 12666154 15893842 17557913 17525996 18251166 15123356 18472094 17900296 17869086 16192424 18376398 16033810 17714472 18418968 17708605 15996030 16015684 12958196 12546737 12609069 12445418 20821823 17481882 18481824 18395914 15052691 12898905 15057751 15818738 18420326 18412020 17565644 12649538 18166357 16638106 18205269 13678700 15650968 10355542 16097048 18705752 16011737 12586293 12632512 17922224 12667390 16116963 17766677 18187930 18317297 18395095 14724832 15362042 17631135 17721639 12741479 17976157 11481614 15931870 18339082 14716833 17944888
MESH:D008107 Liver Diseases Acetaminophen 4.1416610002 19784758 11587558 16611625 12587719 12969438 19014921 19460945
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1417285989 16964402 15830285 15720792 16246199
MESH:D017093 Liver Failure Carbon Tetrachloride 4.6515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.5916871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.5914706259 16899240
MESH:D008113 Liver Neoplasms Aflatoxin B1 8.1015890375 9163691 2125692 18177683
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.1020195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.1019294768
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.688603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 6.6815583823 12014681
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.5014755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.5017053015 18520028 20464547 20064080 6695378 18816296 20135361 18569708 20869020
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5110029692 19755658
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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