AutismKB 2.0

Annotation Detail for AASS


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Basic Information Top
Gene Symbol:AASS ( LKR/SDH,LKRSDH,LORSDH )
Gene Full Name: aminoadipate-semialdehyde synthase
Band: 7q31.32
Quick LinksEntrez ID:10157; OMIM: 605113; Uniprot ID:AASS_HUMAN; ENSEMBL ID: ENSG00000008311; HGNC ID: 17366
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
LYSINE-DEG1-PWYlysine degradation II
Pathway IDPathway Name
hsa00310Lysine degradation
hsa00300Lysine biosynthesis
hsa01100Metabolic pathways
Pathway IDPathway Name
Metabolism of amino acids and derivatives
No data
No data
Pathway IDPathway Name
500781Lysine catabolism
Related Diseases/Disorders Top
Desease IDDesease Name
Inherited disorders of amino acid metabolism
Genetic disorders
H00188Hyperlysinemia
No data
No data
No data
Desease Name
Hyperlysinemia
Saccharopinuria
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of AASS mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of AASS mRNAaffects expression 21346803
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in increased expression of AASS mRNAincreases expression 18648102
D001151 Arsenic Arsenic results in decreased expression of AASS mRNAdecreases expression 19654921
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of AASS mRNAdecreases expression 20106945
C030123 coumarin coumarin results in decreased expression of AASS mRNAdecreases expression 18480146
D016572 Cyclosporine Cyclosporine results in decreased expression of AASS mRNAdecreases expression 20106945
D004958 Estradiol Estradiol results in decreased expression of AASS mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of AASS mRNAdecreases expression 17351261
C056933 fumonisin B1 fumonisin B1 results in decreased expression of AASS mRNAdecreases expression 16221962
C006253 pirinixic acid pirinixic acid results in increased expression of AASS mRNAincreases expression 18445702
D012643 Selenium [Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNAaffects cotreatment|decreases expression 19244175
D012643 Selenium Selenium results in decreased expression of AASS mRNAdecreases expression 19244175
C009250 sevoflurane sevoflurane affects the expression of AASS mRNAaffects expression 15967596
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of AASS mRNAdecreases expression 20106945
D014810 Vitamin E [Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNAaffects cotreatment|decreases expression 19244175
D014810 Vitamin E Vitamin E results in decreased expression of AASS mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9014514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0017505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1518653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 7.0420464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 7.0411473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 7.0414692618
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 6.653712494
MESH:D000236 Adenoma Benzo(a)pyrene 6.656695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.0716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.0716835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.2817306315
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9711748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1219183758
MESH:D020261 Arsenic Poisoning Arsenic 2.8712569548 16251483 16835338 18414634
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5111256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6815885639
MESH:D050197 Atherosclerosis Arsenic 3.2619371607 12928151
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.081440618 11289319
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.8619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8515340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7815746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.7920146248 17474063
MESH:D001943 Breast Neoplasms Estradiol 1.7912948864 14630087 16675129 17018787 17289903 18497071 19861407 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.7920435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.5116111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.9716050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.6115504454 17687452
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.9216705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 8.9216705839
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 8.923581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Arsenic 8.9217306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Estradiol 8.9216924424
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.697296757
MESH:D002294 Carcinoma, Squamous Cell Arsenic 4.7418922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.7420419170
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.1018640142
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3818670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Arsenic 3.4717938729 15738583 19152805
MESH:D002340 Carotid Artery Diseases Arsenic 4.3318022660 16973168
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 16.176135515
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 16.177505956
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 16.1712371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.1718566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1916835633
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 19.3919486331 9022650
MESH:D002779 Cholestasis Cyclosporine 19.3919486331
MESH:D002779 Cholestasis Ethinyl Estradiol 19.3917110522 17681005 15861022 11677210 17333356 16919318 16105132
MESH:D002779 Cholestasis pirinixic acid 19.3919176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.118697196 15668235 16354765 15340226 12621046
MESH:D003092 Colitis Selenium 3.8217936198
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4920055451 15322242 10048152
MESH:D019465 Craniofacial Abnormalities Vitamin E 2.4919769572
MESH:D003490 Cyanosis 2,4-dinitrotoluene 11.0418551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 11.0418551238
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.8418759878 2524372 11298694 8156756 8970840 12868966 11906362 14531868
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4418249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.522952479 3621924
MESH:D003924 Diabetes Mellitus, Type 2 coumarin 4.6119647726
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.6117107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.4419279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 15.3918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.3918551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 15.398291058 16192314 9022650 9328219 18648102 7440962 6482804 1440618 11289319 6679447 9653073 18289764 18692083
MESH:D056486 Drug-Induced Liver Injury fumonisin B1 15.3916221962
MESH:D056486 Drug-Induced Liver Injury Selenium 15.3915131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.3920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7811462148
MESH:C538011 Eales disease Vitamin E 4.779068938
MESH:D004487 Edema pirinixic acid 6.6312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.9616714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.2212538720
MESH:D016889 Endometrial Neoplasms Estradiol 3.0011473722 19148513 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.059294722 10568697
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.383581430
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3816530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0311564622
MESH:D005234 Fatty Liver Cyclosporine 13.1719224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 13.1715345470
MESH:D005234 Fatty Liver pirinixic acid 13.1720131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5011858732
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.086705139
MESH:D005355 Fibrosis Cyclosporine 8.6212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 8.6220067830
MESH:D005534 Foot Diseases Arsenic 5.626392382
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.278708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.077505956
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6610696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.1920471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.1910048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 11.1916080930
MESH:D006333 Heart Failure pirinixic acid 7.0120558911
MESH:D006333 Heart Failure Selenium 7.0117162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3611000095
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.556705139
MESH:D006529 Hepatomegaly fumonisin B1 14.7516221962
MESH:D006529 Hepatomegaly pirinixic acid 14.7518467677 19772884 16221962 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 14.7516120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7116863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.0915709030
MESH:D019584 Hot Flashes Estradiol 10.2617088409
MESH:D019584 Hot Flashes Vitamin E 10.2614716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.118697196 18606429 16959395 15340226 16354765
MESH:D006943 Hyperglycemia pirinixic acid 3.2120558911
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.4817050553
OMIM:238700 HYPERLYSINEMIA marker/mechanism
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 3.9815034207
MESH:D006973 Hypertension Arsenic 8.6411953799 16076760 9931084
MESH:D006973 Hypertension Cyclosporine 8.6410903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.6418670907 18850075
MESH:D006987 Hypesthesia Arsenic 5.6216093927
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5017937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8712878042 12200463
MESH:D007251 Influenza, Human Selenium 11.1716624496
MESH:D007251 Influenza, Human Vitamin E 11.1716624496
MESH:D007333 Insulin Resistance Estradiol 7.2616393666 16627594
MESH:D007333 Insulin Resistance pirinixic acid 7.2616306350
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.088074119 9022650
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3616580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5015604871
MESH:D007642 Keratosis Arsenic 5.0416930632 12749816
MESH:D007674 Kidney Diseases Cyclosporine 10.1510903974 8314463 18776723
MESH:D007674 Kidney Diseases Estradiol 10.1515618244
MESH:D007674 Kidney Diseases Vitamin E 10.1512488133
MESH:D007676 Kidney Failure, Chronic Selenium 3.9116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 23.6016705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 23.6016705839
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 23.606582329
MESH:D007680 Kidney Neoplasms Cyclosporine 23.6012371664
MESH:D007680 Kidney Neoplasms Estradiol 23.6015610895
MESH:D007859 Learning Disorders sevoflurane 4.8119212262
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.5717339181
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2115034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9514716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9512878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.9516169303
MESH:D008107 Liver Diseases Arsenic 2.5511134558
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.357678174
MESH:D008113 Liver Neoplasms Arsenic 14.3516368122
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 14.3520195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 14.3515890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.3516984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 9.872876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 9.873712494 6587162 1399818 598648
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 9.8712151625
MESH:D008171 Lung Diseases Vitamin E 3.1916863852
MESH:D008175 Lung Neoplasms Arsenic 4.8717306315 17976673 19168569
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.8720464547 6695378 18569708 17053015 20064080 18520028 20869020 20135361 18816296
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.8711884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 4.8711062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.0811807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.0815318939
MESH:D020149 Manganese Poisoning Estradiol 4.5519453300
MESH:D008569 Memory Disorders sevoflurane 4.7819212262
MESH:D008654 Mesothelioma Selenium 2.8015107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8516801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2116381670
MESH:D009135 Muscular Diseases pirinixic acid 3.5516239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1519151258
MESH:D017202 Myocardial Ischemia Arsenic 9.0815371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 9.0812213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3216810080
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 8.3216411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 10.5218551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 10.5218551238 7678174
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.483581430
MESH:D009369 Neoplasms Benzo(a)pyrene 4.8611141357
MESH:D009369 Neoplasms pirinixic acid 4.8617405874
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7817289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5017954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3119348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 9.5911399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.5914600291
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 7.436679447
MESH:D009436 Neural Tube Defects Arsenic 7.4316620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.4117056641
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 15.2312819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 15.2316049721
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 15.234026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.083988306
MESH:D010051 Ovarian Neoplasms Arsenic 4.9817306315
MESH:D010051 Ovarian Neoplasms Estradiol 4.9819401270
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7211578682
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.527296757
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3112520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.2116093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.0416905509 6392382 15371236
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.536228378
MESH:D010954 Plasmacytoma Selenium 4.9515087411
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5918163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2512371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2411896295 11118676 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.9120887781
MESH:D011471 Prostatic Neoplasms Arsenic 2.0716140617
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.0717292933
MESH:D011471 Prostatic Neoplasms Estradiol 2.0716740699
MESH:D011471 Prostatic Neoplasms Vitamin E 2.0715084515
MESH:D011507 Proteinuria Arsenic 4.0421343184
MESH:D011537 Pruritus Ethinyl Estradiol 3.3616919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.4019058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8718990726
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.393692021
MESH:C537218 Saccharopinuria marker/mechanism
MESH:D012640 Seizures 2,4-dinitrotoluene 5.9318551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.9318551238
MESH:D012871 Skin Diseases Arsenic 5.0617548696 17050553 19834688 15952646 16702368 17453740 18709164 17938729 6392382 16353154 16759981
MESH:D012871 Skin Diseases Vitamin E 5.0618709164
MESH:D012878 Skin Neoplasms Arsenic 9.5116251483 19538983 17029826 15504454 17050553 17976673
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.5110029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.5116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.0016709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D020521 Stroke Vitamin E 3.5416517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9612697716
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.907505956 6587162 3712494 1399818 6582329
MESH:D013978 Tibial Fractures Estradiol 4.7519048282
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.9216049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.9216049721
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 15.928074119
MESH:D001749 Urinary Bladder Neoplasms Arsenic 15.9218640142 19322015 19429237 11144890 15987713 17306315 17976673
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 15.9217053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 12.1610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 12.1610091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3314692618
MESH:D014605 Uveitis Cyclosporine 4.051336536
MESH:D014652 Vascular Diseases Arsenic 4.7917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6612125929
MESH:D014689 Venous Insufficiency coumarin 5.8412708602
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5715869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3115886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5017120751
Pathway ID Pathway Name
KEGG:00300 Lysine biosynthesis
KEGG:00310 Lysine degradation
KEGG:01100 Metabolic pathways
REACT:13 Metabolism of amino acids and derivatives
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24369
    • No data
    No data
    Releated drug ID Related drug Name
    PA450280l-lysine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00142 - L-Glutamic Acid Dietary supplement;Micronutrient;Non-Essential Amino Acids
    DB00157 - NADH Dietary supplement;Micronutrient
    DB02338 - Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
    DB04207 - N-(5-Amino-5-Carboxypentyl)Glutamic Acid
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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