Annotation Detail for CHST4
Basic Information
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| Gene Symbol: | CHST4 ( GST3,GlcNAc6ST2,HECGLCNAC6ST,LSST ) |
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| Gene Full Name: | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
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| Band: | 16q22.2 |
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| Quick Links | Entrez ID:10164; OMIM: NA; Uniprot ID:CHST4_HUMAN; ENSEMBL ID: ENSG00000140835; HGNC ID: 1972 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00533 | Glycosaminoglycan biosynthesis - keratan sulfate |
| Desease ID | Desease Name |
|---|
| 2213 | Adenocarcinoma, Mucinous |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004052 |
Diethylnitrosamine |
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CHST4 mRNA | affects cotreatment|decreases expression | 17917374
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol results in increased expression of CHST4 mRNA | increases expression | 17557909
|
| C011890 |
kojic acid |
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CHST4 mRNA | affects cotreatment|decreases expression | 17917374
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.81 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.89 | 14692618 |
| MESH:D000236 |
Adenoma |
|
Diethylnitrosamine |
3.08 | 10737359 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Diethylnitrosamine |
4.64 | 19052882 16434500 17620307 19061943 17162532 18056438 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.12 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.91 | 15885639 |
| MESH:D001943 |
Breast Neoplasms |
|
Diethylnitrosamine |
2.19 | 17474063 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Diethylnitrosamine |
1.88 | 20084675 16288022 19335982 3084413 16779866 16807293 11831363 18210153 21159647 19919837 19418558 19701751 19822196 17978847 20512989 19539802 18665156 18393292 10737359 19171122 20524982 18785209 19394651 17173139 18056438 19052882 16681979 18788625 18691550 18506893 20007298 10672840 20432363 16878318 18971187 17055752 3581430 17428255 18978308 19519916 16830150 20935162 16502159 17761372 17162532 20514400 16328049 17138121 20214788 16698587 18494052 16569478 19208518 16540662 19107877 19383236 20727157 20101231 16935385 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Diethylnitrosamine |
3.15 | 2727394 7505956 21159647 17174075 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Diethylnitrosamine |
4.10 | 19052882 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.20 | 16105132 17110522 17681005 15861022 16919318 17333356 11677210 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Diethylnitrosamine |
2.27 | 20387270 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Diethylnitrosamine |
2.15 | 19107877 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.77 | 12538720 |
| MESH:D004931 |
Esophageal Achalasia |
|
Diethylnitrosamine |
5.98 | 16302075 |
| MESH:D005234 |
Fatty Liver |
|
Diethylnitrosamine |
9.35 | 21071580 20387270 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
9.35 | 15345470 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.46 | 16945680 16569931 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.99 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.76 | 17937319 |
| MESH:D007249 |
Inflammation |
|
Diethylnitrosamine |
2.57 | 18785209 |
| MESH:D008103 |
Liver Cirrhosis |
|
Diethylnitrosamine |
3.03 | 18522880 18665156 19638242 20032147 18407596 |
| MESH:D008107 |
Liver Diseases |
|
Diethylnitrosamine |
2.18 | 17034775 |
| MESH:D008113 |
Liver Neoplasms |
|
Diethylnitrosamine |
2.36 | 18648771 9163691 15175105 19812893 19254457 19690152 19996281 18644402 19255062 20452335 20583210 20137499 15885732 19256749 21167192 21047994 19294768 18754104 18977376 19426721 20101389 12112319 10737359 12771043 19427195 19638242 21071580 21278145 19073162 19499222 19642983 19833225 20492335 2422723 20405173 18978307 19551842 20118626 20434301 20501860 19850985 16942905 2862719 19090486 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Diethylnitrosamine |
7.07 | 19009564 18253720 18775883 18164116 18093689 2563599 3124819 17942915 19539802 17854601 18079962 17174075 16267830 19126423 18544905 9362446 18308698 19004024 18282651 19519916 21159647 16842330 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
kojic acid |
7.07 | 18544905 |
| MESH:D008175 |
Lung Neoplasms |
|
Diethylnitrosamine |
1.77 | 21163286 6695378 20970405 20512841 |
| MESH:D009362 |
Neoplasm Metastasis |
|
Diethylnitrosamine |
2.70 | 9029167 3581430 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Diethylnitrosamine |
3.73 | 20387270 |
| MESH:D009461 |
Neurologic Manifestations |
|
Diethylnitrosamine |
5.98 | 20387270 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Diethylnitrosamine |
2.54 | 16540662 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.22 | 11578682 |
| MESH:D011230 |
Precancerous Conditions |
|
Diethylnitrosamine |
3.97 | 2563599 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
4.05 | 15861022 16919318 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.81 | 16709447 |
| MESH:D013274 |
Stomach Neoplasms |
|
Diethylnitrosamine |
1.76 | 18456281 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.15 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.57 | 15669648 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Diethylnitrosamine |
3.32 | 7505956 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.88 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
4.02 | 14671159 15869587 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00533 |
Glycosaminoglycan biosynthesis - keratan sulfate |
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