AutismKB 2.0

Annotation Detail for INADL


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Basic Information Top
Gene Symbol:INADL ( Cipp,FLJ26982,InaD-like,PATJ,hINADL )
Gene Full Name: InaD-like (Drosophila)
Band: 1p31.3
Quick LinksEntrez ID:10207; OMIM: 603199; Uniprot ID:INADL_HUMAN; ENSEMBL ID: ENSG00000132849; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04530Tight junction
Pathway IDPathway Name
Cell junction organization
No data
No data
Pathway IDPathway Name
500122Tight junction interactions
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of INADL proteinaffects expression 20106945
D001554 Benzene Benzene results in decreased expression of INADL mRNAdecreases expression 15120971
15122651
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of INADL mRNAdecreases expression 20106945
D008770 Methylnitrosourea Methylnitrosourea results in increased expression of INADL mRNAincreases expression 15240709
D009151 Mustard Gas Mustard Gas affects the expression of INADL mRNAaffects expression 15651846
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.9020127859 20464547
MESH:D000230 Adenocarcinoma Methylnitrosourea 4.9015113128 15688392
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D000741 Anemia, Aplastic Benzene 4.6414761424 11369114 17661222
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001249 Asthma Mustard Gas 2.7910378619
MESH:D001768 Blister Mustard Gas 5.7019167455
MESH:D001855 Bone Marrow Diseases Benzene 5.8416183116
MESH:D001943 Breast Neoplasms Benzene 2.0911921183 17162533
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0920146248 17474063
MESH:D001943 Breast Neoplasms Methylnitrosourea 2.0916253758 11306469 14633655
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.7015286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.5917687719 10378619
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 1.9821507988 12619106 12907637
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Methylnitrosourea 4.1712484553
MESH:D002471 Cell Transformation, Neoplastic Methylnitrosourea 4.032727394 7505956
MESH:D019465 Craniofacial Abnormalities Benzene 2.4515643154
MESH:D003872 Dermatitis Benzene 5.2515902427
MESH:D004487 Edema Mustard Gas 3.679260866 11428631 11428647 11402378
MESH:D004890 Erythema Mustard Gas 5.709357497
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005354 Fibrosarcoma Methylnitrosourea 5.7711555667
MESH:D005910 Glioma Methylnitrosourea 3.679825942
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006402 Hematologic Diseases Benzene 5.0616183116
MESH:D006973 Hypertension Benzene 3.2017940673
MESH:D007248 Infertility, Male Methylnitrosourea 4.027193160
MESH:D007249 Inflammation Mustard Gas 2.9417524151 16001271 11428620 11402378 9260866 11428647 8975870 9357497 11428631
MESH:D007938 Leukemia Benzene 3.5418335105 15935818 14694614 17119257
MESH:D007951 Leukemia, Myeloid Benzene 4.6917506065
MESH:D015470 Leukemia, Myeloid, Acute Benzene 2.7419478238
MESH:D017880 Limb Deformities, Congenital Methylnitrosourea 4.4515526292
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.9315890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.9320195826 21137059
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.938603461
MESH:D008114 Liver Neoplasms, Experimental Benzene 6.9312562636
MESH:D038061 Lower Extremity Deformities, Congenital Methylnitrosourea 5.9516080182
MESH:D008171 Lung Diseases Mustard Gas 3.6718161513 18702808
MESH:D017563 Lung Diseases, Interstitial Benzene 5.4214698565
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.9814755239
MESH:D008175 Lung Neoplasms Benzene 6.9812562636
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.9820869020 18569708 20064080 17053015 20135361 18816296 6695378 20464547 18520028
MESH:D008175 Lung Neoplasms Methylnitrosourea 6.9818062963
MESH:D008175 Lung Neoplasms Mustard Gas 6.983148597 8781369
MESH:D008223 Lymphoma Benzene 8.8817119257 17584886
MESH:D008223 Lymphoma Methylnitrosourea 8.8816257854 11418001
MESH:D016393 Lymphoma, B-Cell Methylnitrosourea 5.1714633661
MESH:D015674 Mammary Neoplasms, Animal Benzene 4.9812562636
MESH:D008325 Mammary Neoplasms, Experimental Benzene 7.3111921183
MESH:D008325 Mammary Neoplasms, Experimental Methylnitrosourea 7.3111807958 16827153 15113128 16051031 10767621 19196723 16619500 14999141 11751437 15688392 15313902 16944150 12931682 17131329 17020996 14633655 10838139
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009101 Multiple Myeloma Benzene 3.9117119195
MESH:D009369 Neoplasms Benzo(a)pyrene 5.8311141357
MESH:D009369 Neoplasms Methylnitrosourea 5.8315533788
MESH:D009374 Neoplasms, Experimental Methylnitrosourea 4.9512696579
MESH:D009436 Neural Tube Defects Benzene 3.8915643154
MESH:D009442 Neurilemmoma Methylnitrosourea 6.0311555667
MESH:D009503 Neutropenia Mustard Gas 4.377688884 16761898
MESH:D009784 Occupational Diseases Benzene 4.5315727169 17178637 15935809 15576619 15612468 17119257 16737584 17479406 15913788
MESH:D010051 Ovarian Neoplasms Benzene 3.0512562636
MESH:D010190 Pancreatic Neoplasms Methylnitrosourea 3.4616965848
MESH:D011041 Poisoning Mustard Gas 4.2015727166
MESH:D011471 Prostatic Neoplasms marker/mechanism 17013881
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.4117292933
MESH:D011471 Prostatic Neoplasms Methylnitrosourea 3.4115682402 12376480
MESH:D011537 Pruritus Mustard Gas 4.6318058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0310334151 17894541 17720292 17266442 17620002
MESH:D012162 Retinal Degeneration Methylnitrosourea 4.6718155124 18172121
MESH:D012175 Retinoblastoma Methylnitrosourea 6.0311555667
MESH:D012871 Skin Diseases Mustard Gas 2.7812880345 16961503 15451306
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5110029692 19755658
MESH:D013274 Stomach Neoplasms Benzene 3.6812562636
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.682093021 20155912
MESH:D013274 Stomach Neoplasms Methylnitrosourea 3.6816257854 18593901 15930296
MESH:D013953 Thymus Neoplasms Benzene 14.0910850423
MESH:D013953 Thymus Neoplasms Methylnitrosourea 14.0911418001
MESH:D013964 Thyroid Neoplasms Methylnitrosourea 4.197505956 3078959
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014594 Uterine Neoplasms Benzene 4.7712562636
Pathway ID Pathway Name
REACT:20676 Cell junction organization
KEGG:04530 Tight junction
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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