Annotation Detail for USPL1
Basic Information
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| Gene Symbol: | USPL1 ( C13orf22,D13S106E,DKFZp781K2286,FLJ32952,RP11-121O19.1,bA121O19.1 ) |
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| Gene Full Name: | ubiquitin specific peptidase like 1 |
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| Band: | 13q12.3 |
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| Quick Links | Entrez ID:10208; OMIM: NA; Uniprot ID:USPL1_HUMAN; ENSEMBL ID: ENSG00000132952; HGNC ID: 20294 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of USPL1 mRNA | affects expression | 17562736
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of USPL1 mRNA | increases expression | 20106945
|
| D008628 |
Mercury |
Mercury results in increased expression of USPL1 mRNA | increases expression | 16823088
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of USPL1 mRNA | increases expression | 18301758
|
| D012643 |
Selenium |
Selenium results in decreased expression of USPL1 mRNA | decreases expression | 19244175
|
| D014810 |
Vitamin E |
Vitamin E results in decreased expression of USPL1 mRNA | decreases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.47 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.94 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.36 | 10982225 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
2.14 | 18445737 |
| MESH:D001321 |
Autistic Disorder |
|
Mercury |
2.14 | 17497416 |
| MESH:D001327 |
Autoimmune Diseases |
|
Mercury |
5.29 | 16634805 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.47 | 19483382 |
| MESH:D002252 |
Carbon Tetrachloride Poisoning |
|
Vitamin E |
4.35 | 16050911 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002311 |
Cardiomyopathy, Dilated |
|
Mercury |
3.54 | 10334427 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.75 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.73 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
8.53 | 19486331 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
8.53 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.20 | 17936198 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Vitamin E |
1.92 | 19769572 |
| MESH:D017449 |
Dermatitis, Allergic Contact |
|
Mercury |
4.20 | 16823706 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.55 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.04 | 19739265 12540782 12392966 11739529 16177239 11743745 11834606 11287661 16227642 12153990 16393943 17906064 14986274 10663392 12594235 11529661 16109766 18713872 19085960 10915739 15619225 12705907 19420014 14550746 12958197 16081117 17562736 10774834 19164858 19923254 16485898 14725611 2444490 16781746 17522070 11421492 18071297 19370779 11461765 15968718 19416960 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.04 | 15131321 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.62 | 19426721 |
| MESH:C538011 |
Eales disease |
|
Vitamin E |
5.22 | 9068938 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.80 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
8.66 | 19224547 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.66 | 20131406 19236843 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.56 | 12168785 12639820 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.19 | 16983495 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.68 | 8708960 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Vitamin E |
3.13 | 16080930 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.55 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.55 | 17162251 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.88 | 15720958 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.41 | 18467677 19772884 16221962 19176532 |
| MESH:D006548 |
Hernia, Diaphragmatic |
|
Vitamin E |
2.79 | 16490937 16863852 |
| MESH:D019584 |
Hot Flashes |
|
Vitamin E |
4.49 | 14716179 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.95 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.49 | 20558911 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.19 | 10903974 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
12.76 | 16624496 |
| MESH:D007251 |
Influenza, Human |
|
Vitamin E |
12.76 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.82 | 16306350 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
4.96 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
15.85 | 12587719 15629191 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
15.85 | 18776723 10903974 8314463 |
| MESH:D007674 |
Kidney Diseases |
|
Mercury |
15.85 | 17934191 |
| MESH:D007674 |
Kidney Diseases |
|
Vitamin E |
15.85 | 12488133 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.21 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.00 | 12371664 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
2.45 | 15474484 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
Vitamin E |
2.45 | 16169303 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 12587719 19014921 16610002 12969438 19784758 19460945 11587558 16611625 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.54 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
1.91 | 20007298 15890375 16377806 |
| MESH:D008171 |
Lung Diseases |
|
Vitamin E |
3.37 | 16863852 |
| MESH:D008175 |
Lung Neoplasms |
|
Vitamin E |
1.90 | 11062179 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.95 | 15318939 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.98 | 19513568 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.89 | 15107826 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.31 | 16801185 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.92 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.25 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.19 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.08 | 17405874 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
4.96 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.57 | 19348381 18481113 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.14 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.87 | 20558911 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.65 | 16870215 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.41 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.51 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Vitamin E |
3.25 | 15084515 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.31 | 16882103 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.52 | 19058328 |
| MESH:D012871 |
Skin Diseases |
|
Vitamin E |
2.50 | 18709164 |
| MESH:D020521 |
Stroke |
|
Vitamin E |
3.77 | 16517955 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.33 | 10982225 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.50 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
4.96 | 17120751 |
Related Pathway Information