AutismKB 2.0

Annotation Detail for ZNF443


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Basic Information Top
Gene Symbol:ZNF443 ( ZK1 )
Gene Full Name: zinc finger protein 443
Band: 19p13.2
Quick LinksEntrez ID:10224; OMIM: 606697; Uniprot ID:ZN443_HUMAN; ENSEMBL ID: ENSG00000180855; HGNC ID: 20878
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2007Liver tumor
2022Liver cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF443 mRNAdecreases expression 20382639
D004040 Dietary Carbohydrates Dietary Carbohydrates results in increased expression of ZNF443 mRNAincreases expression 17490981
D018038 Sodium Selenite Sodium Selenite results in increased expression of ZNF443 mRNAincreases expression 18175754
C004648 testosterone enanthate testosterone enanthate affects the expression of ZNF443 mRNAaffects expression 17440010
D014810 Vitamin E Vitamin E results in decreased expression of ZNF443 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.9620889678
MESH:D019457 Chromosome Breakage Sodium Selenite 5.2415894690
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1016285004
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3615131321
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1420426865
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1516080930
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016863852 16490937
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 6.3617440010
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D007251 Influenza, Human Vitamin E 4.8316624496
MESH:D007333 Insulin Resistance Sodium Selenite 3.4914714311
MESH:D007674 Kidney Diseases Vitamin E 2.9812488133
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 1.9016169303
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4614737004
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.2718760546
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2715084515
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D020521 Stroke Vitamin E 3.8116517955
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018