AutismKB 2.0

Annotation Detail for HNRNPR


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:HNRNPR ( FLJ25714,HNRPR,hnRNP R,hnRNP-R )
Gene Full Name: heterogeneous nuclear ribonucleoprotein R
Band: 1p36.12
Quick LinksEntrez ID:10236; OMIM: 607201; Uniprot ID:HNRPR_HUMAN; ENSEMBL ID: ENSG00000125944; HGNC ID: 5047
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
mRNA Processing
Gene Expression
No data
No data
Pathway IDPathway Name
500866mRNA Splicing - Major Pathway
500655Processing of Capped Intron-Containing Pre-mRNA
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C109238 acyline acyline results in increased expression of HNRNPR mRNAincreases expression 17510436
D000643 Ammonium Chloride Ammonium Chloride affects the expression of HNRNPR mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of HNRNPR proteindecreases expression 20097212
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HNRNPR mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of HNRNPR mRNAaffects cotreatment|decreases expression 20360939
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 7.256695378
MESH:D000236 Adenoma Diethylnitrosamine 7.256695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.4418056438 19052882 16434500 19061943 17162532 17620307
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0520146248 17474063
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.0517474063
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.8717978847 16830150 17138121 21159647 16288022 19383236 18506893 18494052 17761372 16698587 17173139 20084675 19171122 20101231 3084413 16807293 16878318 3581430 20214788 18665156 16935385 19335982 20514400 16779866 16569478 20935162 19052882 18056438 20727157 17162532 19701751 17428255 18393292 11831363 19539802 19519916 18210153 19418558 16502159 20524982 16328049 19822196 18788625 19107877 19919837 16681979 17055752 18971187 19208518 18978308 20432363 19394651 18785209 20007298 20512989 18691550 10737359 10672840 16540662
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.0917174075 7505956 21159647 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0119052882
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2520387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1319107877
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.7316302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Diethylnitrosamine 3.5621071580 20387270
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D007249 Inflammation Diethylnitrosamine 2.5318785209
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.9310783313
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.7315369732
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.2116766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9918665156 19638242 18522880 18407596 20032147
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1617034775
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 4.8921137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 4.8912112319 19833225 12771043 16942905 21278145 19642983 20452335 20405173 19812893 15885732 19638242 19255062 20137499 19073162 19499222 20434301 19254457 10737359 19294768 19090486 18754104 18978307 18977376 2422723 19426721 19850985 20101389 20118626 18648771 19996281 19690152 20583210 18644402 2862719 15175105 20492335 20501860 21047994 21167192 9163691 19427195 19256749 21071580 19551842
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.8319539802 9362446 16267830 16842330 19009564 18253720 18775883 19004024 18079962 19126423 18544905 18093689 19519916 3124819 17854601 17174075 2563599 21159647 18282651 18308698 18164116 17942915
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 2.4620869020 18569708 17053015 18816296 20135361 20464547 20064080 6695378 18520028
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.4620970405 21163286 20512841 6695378
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.689029167 3581430
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3111141357
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6520387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.7320387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5216540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.882563599
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5119755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.402093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4018456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.257505956
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
Pathway ID Pathway Name
REACT:71 Gene Expression
REACT:1675 mRNA Processing
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved