AutismKB 2.0

Annotation Detail for SLC35B1


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Basic Information Top
Gene Symbol:SLC35B1 ( UGTREL1 )
Gene Full Name: solute carrier family 35, member B1
Band: 17q21.33
Quick LinksEntrez ID:10237; OMIM: 610790; Uniprot ID:S35B1_HUMAN; ENSEMBL ID: ENSG00000121073; HGNC ID: 20798
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of SLC35B1 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of SLC35B1 mRNAaffects expression 17562736
C095105 bexarotene bexarotene results in increased expression of SLC35B1 mRNAincreases expression 16648578
D016572 Cyclosporine Cyclosporine results in increased expression of SLC35B1 mRNAincreases expression 20106945
D000431 Ethanol Ethanol results in increased expression of SLC35B1 mRNAincreases expression 15353170
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of SLC35B1 mRNAincreases expression 17616710
D018038 Sodium Selenite Sodium Selenite results in increased expression of SLC35B1 mRNAincreases expression 18175754
D014303 Trinitrotoluene Trinitrotoluene affects the expression of SLC35B1 mRNAaffects expression 21346803
D014415 Tunicamycin Tunicamycin results in increased expression of SLC35B1 mRNAincreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 9.9318926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 9.937525203
MESH:D000138 Acidosis Ethanol 4.7811192467
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.6415451039 15451040
MESH:D000799 Angioedema Acetaminophen 4.1610982225
MESH:D000853 Anophthalmos Ethanol 5.0815513904
MESH:D001008 Anxiety Disorders Ethanol 4.1711141031
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms bexarotene 2.9716818667 16344269
MESH:D002056 Burns Ethanol 4.9116374292
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 4.7516705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.753084413
MESH:D006528 Carcinoma, Hepatocellular Ethanol 4.7515763234 15289165 18788625
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.2916247446
MESH:D006332 Cardiomegaly Ethanol 3.5419332462
MESH:D002386 Cataract Acetaminophen 7.8810977129
MESH:D002386 Cataract Trinitrotoluene 7.8815817613 14694615
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.6612371664
MESH:D002779 Cholestasis Cyclosporine 3.0619486331
MESH:D019457 Chromosome Breakage Sodium Selenite 5.0115894690
MESH:D002971 Cleft Lip Ethanol 3.6815513904
MESH:D002972 Cleft Palate Ethanol 3.2515513904
MESH:D000013 Congenital Abnormalities Trinitrotoluene 4.5815095906
MESH:D019465 Craniofacial Abnormalities Ethanol 2.3310194807 19302082 15513904 11198716 15451040 15451039 11873399
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.1118551238
MESH:D003490 Cyanosis Trinitrotoluene 12.1118551238
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.9616285004
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 12.6218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 12.6211529661 18071297 16393943 16781746 15968718 12958197 12540782 11421492 19420014 10915739 19085960 17522070 18713872 17906064 12594235 19416960 16177239 11287661 10774834 11461765 19164858 12705907 19370779 12153990 14550746 10663392 15619225 19739265 12392966 14725611 14986274 16109766 16227642 11834606 11743745 17562736 16081117 16485898 19923254 11739529 2444490
MESH:D056486 Drug-Induced Liver Injury Ethanol 12.6211566570
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 12.6215131321
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 12.6218551238 21346803
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4219426721
MESH:D004938 Esophageal Neoplasms Ethanol 5.0316704527
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 5.0315878914 15623463 15547733 16805852 15150132 15547721 16510608 16704527 15264214
MESH:D005234 Fatty Liver Cyclosporine 8.6119224547
MESH:D005234 Fatty Liver Ethanol 8.6119236843 18620774 16409862
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.9817920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.5816946407 10194807 15451040 15513904
MESH:D005355 Fibrosis Cyclosporine 3.4012168785 12639820
MESH:D005756 Gastritis Acetaminophen 12.2116983495
MESH:D005756 Gastritis Ethanol 12.2115046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.508708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7115720958
MESH:D006529 Hepatomegaly Trinitrotoluene 4.4915817613
MESH:D006930 Hyperalgesia Acetaminophen 8.3616870215
MESH:D006930 Hyperalgesia Ethanol 8.3618783367
MESH:D006973 Hypertension Cyclosporine 2.1610903974
MESH:D007248 Infertility, Male Trinitrotoluene 3.8012150543
MESH:D007333 Insulin Resistance Sodium Selenite 3.4014714311
MESH:D007569 Jaw Abnormalities Ethanol 4.6115513904
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.7615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.1615629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.1618776723 8314463 10903974
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 7.8516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 7.8512371664
MESH:D007859 Learning Disorders Ethanol 4.4715451040
MESH:D017880 Limb Deformities, Congenital Ethanol 3.9617676605
MESH:D008103 Liver Cirrhosis Ethanol 3.4715289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.3818295389
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 2.3118166357
MESH:D008107 Liver Diseases Acetaminophen 1.6711587558 12969438 19014921 16610002 19460945 16611625 19784758 12587719
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.9117347304 17207112
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4317185352 16871587
MESH:D008175 Lung Neoplasms bexarotene 2.5217849452
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.2814737004
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.4111161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 3.5319196723 19196722 15591091
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8319513568
MESH:D008569 Memory Disorders Ethanol 4.4218411066 15451040
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1116801185
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.6518551238
MESH:D009336 Necrosis Trinitrotoluene 11.6518551238
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 5.1019196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.7617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.4719348381 18481113
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0418514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.8716049721 12819281
MESH:D009784 Occupational Diseases Trinitrotoluene 9.8714694615 12819281 17852074
MESH:D010146 Pain Acetaminophen 2.5616870215
MESH:D010190 Pancreatic Neoplasms Ethanol 3.0312384795
MESH:D011230 Precancerous Conditions Cyclosporine 3.4012371664
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3618760546
MESH:D011565 Psoriasis Cyclosporine 2.2916882103
MESH:D012640 Seizures 2,4-dinitrotoluene 10.8018551238
MESH:D012640 Seizures Ethanol 10.809754883
MESH:D012640 Seizures Trinitrotoluene 10.8018551238
MESH:D013163 Splenomegaly Trinitrotoluene 5.4615817613
MESH:D013274 Stomach Neoplasms Ethanol 2.8618456281
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.8612958204 17575124
MESH:D013276 Stomach Ulcer Ethanol 3.739211565 17918041 9562338 11906479 17189318 16755016
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.459754883
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 2.3516049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.6010091137
MESH:D014581 Urticaria Acetaminophen 3.2010982225
MESH:D014605 Uveitis Cyclosporine 4.301336536
MESH:D014985 Xerophthalmia Cyclosporine 4.7617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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