AutismKB 2.0

Annotation Detail for DNAJA2


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Basic Information Top
Gene Symbol:DNAJA2 ( CPR3,DJ3,DJA2,DNAJ,DNJ3,HIRIP4,PRO3015,RDJ2 )
Gene Full Name: DnaJ (Hsp40) homolog, subfamily A, member 2
Band: 16q11.2
Quick LinksEntrez ID:10294; OMIM: 611322; Uniprot ID:DNJA2_HUMAN; ENSEMBL ID: ENSG00000069345; HGNC ID: 14884
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
hsa04141Protein processing in endoplasmic reticulum
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of DNAJA2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of DNAJA2 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DNAJA2 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of DNAJA2 mRNAdecreases expression 19150397
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNAaffects cotreatment|decreases expression 18544905
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DNAJA2 mRNAaffects cotreatment|increases expression 18544905
D004052 Diethylnitrosamine [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNAaffects cotreatment|decreases expression 18253720
D011345 Fenofibrate [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNAaffects cotreatment|decreases expression 18253720
D016627 Oxidopamine Oxidopamine results in increased expression of DNAJA2 mRNAincreases expression 12486162
D007213 Indomethacin Indomethacin results in decreased expression of DNAJA2 mRNAdecreases expression 16984733
D007213 Indomethacin Indomethacin results in increased expression of DNAJA2 mRNAincreases expression 18299717
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNAaffects cotreatment|decreases expression 18544905
C011890 kojic acid [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DNAJA2 mRNAaffects cotreatment|increases expression 18544905
C008281 limonene limonene results in increased expression of DNAJA2 mRNAincreases expression 12815608
D009151 Mustard Gas Mustard Gas results in increased expression of DNAJA2 mRNAincreases expression 15674844
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of DNAJA2 mRNAincreases expression 17616710
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of DNAJA2 mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of DNAJA2 mRNAincreases expression 17426115
18301758
C052785 rebamipide rebamipide results in increased expression of DNAJA2 mRNAincreases expression 18299717
D014501 Uranium Uranium affects the expression of DNAJA2 mRNAaffects expression 15672453
C005460 uranyl acetate uranyl acetate affects the expression of DNAJA2 mRNAaffects expression 15672453
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018