AutismKB 2.0

Annotation Detail for SNAPC5


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Basic Information Top
Gene Symbol:SNAPC5 ( SNAP19 )
Gene Full Name: small nuclear RNA activating complex, polypeptide 5, 19kDa
Band: 15q22.31
Quick LinksEntrez ID:10302; OMIM: 605979; Uniprot ID:SNPC5_HUMAN; ENSEMBL ID: ENSG00000174446; HGNC ID: 15484
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane affects the expression of SNAPC5 mRNAaffects expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of SNAPC5 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in decreased expression of SNAPC5 mRNAdecreases expression 20458559
C017947 sodium arsenite sodium arsenite results in increased expression of SNAPC5 mRNAincreases expression 17879257
D013654 Taurine Taurine results in increased expression of SNAPC5 mRNAincreases expression 16579726
C025643 vinclozolin vinclozolin affects the expression of SNAPC5 mRNAaffects expression 19015723
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3411798837 19825857
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.923712494
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.2215276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.4217306315 16712894
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.8919015723
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.5411289319 1440618
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.0016206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.6811589617
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.907296757 3581430
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.903084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.9014691202 16217749 15553829 15073043 11135700
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 6.9016507464 15276417 17306315
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4019014326
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.807296757
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4212490120
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4518572023
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 7.447505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 7.4420056578 19524636
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.3819486331 9022650
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.5712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003456 Cryptorchidism vinclozolin 4.7214966744
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.4515213294
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.2111298694 8156756 8970840 2524372 11906362 14531868 12868966 18759878
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.842952479 3621924
MESH:D058065 Diabetic Cardiomyopathies Taurine 6.5216025228
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.846679447 18289764 16192314 9328219 9022650 8291058 18692083 1440618 6482804 18648102 9653073 11289319 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.842444490 11461765 19739265 18071297 11743745 16177239 12153990 10774834 14725611 11834606 10663392 16227642 19416960 17906064 11529661 17562736 15619225 16393943 16781746 11287661 19923254 16109766 14550746 15968718 11739529 12705907 18713872 19420014 12540782 19164858 12392966 12958197 16485898 19370779 10915739 19085960 17522070 16081117 11421492 12594235 14986274
MESH:D056486 Drug-Induced Liver Injury Taurine 6.849328219
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.693581430
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6912903497
MESH:D005234 Fatty Liver arsenic trioxide 3.6115073043
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.546705139
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.6416904648
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.4016973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.8216417039
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.1416452187
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.397505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.896705139
MESH:D006689 Hodgkin Disease sodium arsenite 3.4312676792
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.3615034207
MESH:D007248 Infertility, Male sodium arsenite 7.5212646999 15346721
MESH:D007248 Infertility, Male vinclozolin 7.5216467254
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.548074119 9022650
MESH:D007674 Kidney Diseases Acetaminophen 6.5112587719 15629191
MESH:D007674 Kidney Diseases sodium arsenite 6.5120008137
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.236582329
MESH:D007938 Leukemia arsenic trioxide 2.9615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1217077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.7716972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1819850784 16968895 20471514 16467208 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4116112521 17869043 19035177 19225113 19642359 16966277 17712046 16891316 17217047 19075265 16823087 12679006 12712474 12018890 16330433 15213294 15336539 15622746 16331271 11161223 15748426 17107899 17649720 11468182 9834237
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7316882451
MESH:D007984 Leydig Cell Tumor vinclozolin 5.1916417039
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.3815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Taurine 3.2715893842 15931870
MESH:D008107 Liver Diseases Acetaminophen 1.6916611625 19784758 19460945 19014921 16610002 12969438 11587558 12587719
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 5.0114682389
MESH:D008113 Liver Neoplasms sodium arsenite 5.0116712894 15276417
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.57598648 6587162 1399818 3712494
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.5720377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.5915213294
MESH:D008171 Lung Diseases sodium arsenite 3.3719095001
MESH:D008175 Lung Neoplasms arsenic trioxide 2.6111798837 19825857
MESH:D008175 Lung Neoplasms sodium arsenite 2.6117077188 19931552 15276417 17306315 16712894
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3215949261 11468182 14977855 19417148 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.1918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3016105982 16882451
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.3416624393
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.573581430
MESH:D009369 Neoplasms sodium arsenite 2.6311559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.0820056578
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 13.286679447
MESH:D009436 Neural Tube Defects arsenic trioxide 13.2810525206
MESH:D009436 Neural Tube Defects sodium arsenite 13.2812854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.724026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.543988306
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.1819769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.1815276417 17306315
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6115580305
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.907296757
MESH:D010235 Paraganglioma arsenic trioxide 4.5119927285
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.996228378
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.3618042343 19015723 18220299
MESH:D011469 Prostatic Diseases vinclozolin 5.4018220299
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2319131511
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2316039940
MESH:D011472 Prostatitis vinclozolin 5.4018629315
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.613692021
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.3416646077
MESH:D012878 Skin Neoplasms sodium arsenite 2.8218572023 19524636
MESH:D016135 Spinal Dysraphism sodium arsenite 4.0412854658
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 7.976582329 1399818 6587162 3712494 7505956
MESH:D013964 Thyroid Neoplasms arsenic trioxide 7.9719014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.4215213294
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 8.948074119
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.9412973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 8.9417306315 11723127 16452187 16712894
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.0711813266
MESH:D014652 Vascular Diseases sodium arsenite 4.8917056641
Pathway ID Pathway Name
REACT:1788 Transcription
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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