AutismKB 2.0

Annotation Detail for ZNF267


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF267 ( HZF2 )
Gene Full Name: zinc finger protein 267
Band: 16p11.2
Quick LinksEntrez ID:10308; OMIM: 604752; Uniprot ID:ZN267_HUMAN; ENSEMBL ID: ENSG00000185947; HGNC ID: 13060
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1712Yersinia infection
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ZNF267 proteinaffects expression 20106945
D001151 Arsenic Arsenic results in decreased expression of ZNF267 mRNAdecreases expression 16835338
D016572 Cyclosporine Cyclosporine results in increased expression of ZNF267 mRNAincreases expression 20106945
C008493 methylselenic acid methylselenic acid results in increased expression of ZNF267 mRNAincreases expression 12517777
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D018246 Adrenocortical Adenoma Arsenic 5.9417306315
MESH:D020261 Arsenic Poisoning marker/mechanism 16835338
MESH:D020261 Arsenic Poisoning Arsenic 2.9516835338 16251483 18414634 12569548
MESH:D050197 Atherosclerosis Arsenic 3.4619371607 12928151
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.7817687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 3.3721507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Arsenic 3.3716507464 17306315
MESH:D002294 Carcinoma, Squamous Cell Arsenic 2.7717687452 15504454 18922899
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.4718640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7115738583 19152805 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.6818022660 16973168
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7912371664
MESH:D002779 Cholestasis Cyclosporine 3.2119486331
MESH:D005234 Fatty Liver Cyclosporine 3.2819224547
MESH:D005355 Fibrosis Cyclosporine 3.7012168785 12639820
MESH:D005534 Foot Diseases Arsenic 6.286392382
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.858708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.0515720958
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.8517050553
MESH:D006973 Hypertension Arsenic 5.7116076760 11953799 9931084
MESH:D006973 Hypertension Cyclosporine 5.7110903974
MESH:D006987 Hypesthesia Arsenic 6.2816093927
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.1615604871
MESH:D007642 Keratosis Arsenic 5.6216930632 12749816
MESH:D007674 Kidney Diseases Cyclosporine 2.548314463 18776723 10903974
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0812371664
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.7917339181
MESH:D008107 Liver Diseases Arsenic 2.6111134558
MESH:D008113 Liver Neoplasms Aflatoxin B1 5.2015890375 9163691 2125692 18177683
MESH:D008113 Liver Neoplasms Arsenic 5.2016368122
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 2.968603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.7414755239
MESH:D008175 Lung Neoplasms Arsenic 2.7417976673 19168569 17306315
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.5116801185
MESH:D017202 Myocardial Ischemia Arsenic 4.3115371236
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.1617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6519348381 18481113
MESH:D009436 Neural Tube Defects Arsenic 3.6916620997
MESH:D020078 Neurogenic Inflammation Arsenic 4.8417056641
MESH:D010051 Ovarian Neoplasms Arsenic 2.8417306315
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.6816093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.626392382 15371236 16905509
MESH:D011230 Precancerous Conditions Cyclosporine 3.5912371664
MESH:D011471 Prostatic Neoplasms Arsenic 3.5616140617
MESH:D011471 Prostatic Neoplasms methylselenic acid 3.5616205645
MESH:D011507 Proteinuria Arsenic 4.4721343184
MESH:D011565 Psoriasis Cyclosporine 2.3316882103
MESH:D012871 Skin Diseases marker/mechanism 16835338
MESH:D012871 Skin Diseases Arsenic 2.8217938729 18709164 17050553 16353154 17548696 16702368 17453740 19834688 15952646 16759981 6392382
MESH:D012878 Skin Neoplasms Arsenic 3.1617976673 17029826 15504454 16251483 19538983 17050553
MESH:D001749 Urinary Bladder Neoplasms Arsenic 2.9417976673 19429237 15987713 18640142 17306315 11144890 19322015
MESH:D014605 Uveitis Cyclosporine 4.711336536
MESH:D014652 Vascular Diseases Arsenic 5.3717056641
MESH:D014985 Xerophthalmia Cyclosporine 5.1617120751
Pathway ID Pathway Name
REACT:71 Gene Expression
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved