AutismKB 2.0

Annotation Detail for CDKN2C


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Basic Information Top
Gene Symbol:CDKN2C ( INK4C,p18,p18-INK4C )
Gene Full Name: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Band: 1p32.3
Quick LinksEntrez ID:1031; OMIM: 603369; Uniprot ID:CDN2C_HUMAN; ENSEMBL ID: ENSG00000123080; HGNC ID: 1789
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04110Cell cycle
Pathway IDPathway Name
Cell Cycle, Mitotic
Pathway IDPathway Name
200027E2F transcription factor network
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of CDKN2C mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CDKN2C mRNAaffects expression 16483693
D047310 Apigenin Apigenin results in increased expression of CDKN2C mRNAincreases expression 18331776
C006632 arsenic trioxide arsenic trioxide results in increased expression of CDKN2C mRNAincreases expression 17530438
C015001 arsenite arsenite results in decreased expression of CDKN2C mRNAdecreases expression 18929588
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CDKN2C mRNAdecreases expression 20382639
C053541 bicalutamide bicalutamide results in decreased expression of CDKN2C mRNAdecreases expression 15638997
C006780 bisphenol A bisphenol A results in decreased expression of CDKN2C mRNAdecreases expression 16474171
C005961 bis(tri-n-butyltin)oxide bis(tri-n-butyltin)oxide results in decreased expression of CDKN2C mRNAdecreases expression 17553608
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of CDKN2C mRNAdecreases expression 15336504
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNAaffects cotreatment|decreases expression 20360939
C043561 chrysin chrysin results in decreased expression of CDKN2C mRNAdecreases expression 18331776
D016572 Cyclosporine Cyclosporine results in decreased expression of CDKN2C mRNAdecreases expression 20106945
D019259 Lamivudine [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNAaffects cotreatment|decreases expression 15784690
D004052 Diethylnitrosamine AHR protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CDKN2C mRNA]decreases expression|decreases reaction 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of CDKN2C mRNAdecreases expression 19996281
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of CDKN2C mRNAincreases expression 18282651
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CDKN2C mRNAaffects cotreatment|decreases expression 20360939
D004317 Doxorubicin CDKN2C protein affects the susceptibility to Doxorubicinaffects response to substance 16217747
D004391 Dust Dust results in decreased expression of CDKN2C mRNAdecreases expression 17805423
D004958 Estradiol Estradiol results in decreased expression of CDKN2C mRNAdecreases expression 16474171
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of CDKN2C mRNAdecreases expression 17351261
D005472 Fluorouracil Fluorouracil results in decreased expression of CDKN2C mRNAdecreases expression 16557594
D019833 Genistein Genistein results in decreased expression of CDKN2C mRNAdecreases expression 16474171
D007529 Isoflavones Isoflavones results in decreased expression of CDKN2C mRNAdecreases expression 17374662
C006552 kaempferol kaempferol results in decreased expression of CDKN2C mRNAdecreases expression 18331776
D007657 Ketone Bodies Ketone Bodies results in decreased expression of CDKN2C mRNAdecreases expression 16807920
D047311 Luteolin Luteolin results in decreased expression of CDKN2C mRNAdecreases expression 18331776
D008345 Manganese Manganese results in decreased expression of CDKN2C mRNAdecreases expression 17175027
C025340 manganese chloride manganese chloride results in decreased expression of CDKN2C mRNAdecreases expression 17175027
C040015 myricetin myricetin results in increased expression of CDKN2C mRNAincreases expression 18331776
D017239 Paclitaxel CDKN2C protein affects the susceptibility to Paclitaxelaffects response to substance 16217747
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of CDKN2C mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of CDKN2C mRNAincreases expression 19270015
19482888
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in decreased expression of CDKN2C mRNAdecreases expression 16474171
C025299 polyphenols polyphenols results in decreased expression of CDKN2C mRNAdecreases expression 16293270
D011374 Progesterone Progesterone results in increased expression of CDKN2C mRNAincreases expression 18070364
D011794 Quercetin Quercetin results in increased expression of CDKN2C mRNAincreases expression 18331776
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CDKN2C mRNAincreases expression 15667827
D013755 Tetradecanoylphorbol Acetate [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNAaffects cotreatment|affects expression 16979875
C496197 trans-10,cis-12-conjugated linoleic acid trans-10,cis-12-conjugated linoleic acid results in decreased expression of CDKN2C mRNAdecreases expression 17951470
D014212 Tretinoin Tretinoin results in increased expression of CDKN2C mRNAincreases expression 16140955
C113580 U 0126 U 0126 results in increased expression of CDKN2C proteinincreases expression 15930308
C066075 vanadium pentoxide vanadium pentoxide results in decreased expression of CDKN2C mRNAdecreases expression 17459161
D014747 Vinblastine CDKN2C protein affects the susceptibility to Vinblastineaffects response to substance 16217747
D015215 Zidovudine [Zidovudine co-treated with Lamivudine] results in decreased expression of CDKN2C mRNAaffects cotreatment|decreases expression 15784690
D015032 Zinc [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CDKN2C mRNAaffects cotreatment|affects expression 16979875
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 6.806195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 6.8014514962 11752688 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.1118287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.4817505938
MESH:D000163 Acquired Immunodeficiency Syndrome Zidovudine 4.389612607
MESH:D000168 Acrocephalosyndactylia U 0126 5.0317694057
MESH:D000169 Acrodermatitis Zinc 4.9517190629 17202136 16889938
MESH:D000230 Adenocarcinoma arsenic trioxide 15.3511798837 19825857
MESH:D000230 Adenocarcinoma Doxorubicin 15.3517418594
MESH:D000230 Adenocarcinoma Estradiol 15.3511473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 15.3514692618
MESH:D000230 Adenocarcinoma Fluorouracil 15.3517638652
MESH:D000230 Adenocarcinoma Genistein 15.3511473722
MESH:D000236 Adenoma Diethylnitrosamine 2.586695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 14.7116434500 17620307 19061943 17162532 18056438 19052882
MESH:D018248 Adenoma, Liver Cell Phenobarbital 14.7117620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.7116835633
MESH:D000419 Albuminuria Doxorubicin 4.1121441931
MESH:D000505 Alopecia Isoflavones 8.3817569567
MESH:D000505 Alopecia Tretinoin 8.3815955085
MESH:D000544 Alzheimer Disease Zinc 2.6516325427 16580781 17119284 16410023
MESH:D000740 Anemia Fluorouracil 7.3815504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.3811748828
MESH:D000743 Anemia, Hemolytic Quercetin 3.8317084956
MESH:D000755 Anemia, Sickle Cell Zinc 4.4716916123
MESH:D000756 Anemia, Sideroblastic Manganese 9.6816910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 9.6816910769
MESH:D000799 Angioedema Acetaminophen 3.3810982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.2415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.2416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1516292516
MESH:D001249 Asthma Tretinoin 4.5416456186
MESH:D001249 Asthma Zinc 4.5417085522
MESH:D001260 Ataxia Telangiectasia Quercetin 4.5215336622
MESH:D001321 Autistic Disorder Acetaminophen 1.4718445737
MESH:D001327 Autoimmune Diseases Quercetin 3.9619761891
MESH:D001471 Barrett Esophagus Tretinoin 3.9716935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 12.9916206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 12.9912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 12.9916206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3315340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.4615746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2414601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.1515867366
MESH:D001862 Bone Resorption bisphenol A 3.4611985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 4.8717868700
MESH:D001930 Brain Injuries Progesterone 9.5715845082 15665606 15380490
MESH:D001930 Brain Injuries Zinc 9.5717109824
MESH:D001932 Brain Neoplasms Doxorubicin 3.4217150277
MESH:D001943 Breast Neoplasms Apigenin 10.3116541309 17132221
MESH:D001943 Breast Neoplasms bisphenol A 10.3117123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 10.3117474063
MESH:D001943 Breast Neoplasms Doxorubicin 10.3118234424 17426702 16115903 16264153 15993339 15939500 17369602 16935488 16826403 16322301 15692762 15567936 17983394 19526202 11325840 15634643 15994142 18695136 18382427 15136595 16595493 18628466 16096432 15668708
MESH:D001943 Breast Neoplasms Estradiol 10.3116675129 17289903 19861407 17261762 18497071 14630087 17018787 12948864
MESH:D001943 Breast Neoplasms Fluorouracil 10.3118608205 15136595 16110121 16595493 16557594 19217205 18357371
MESH:D001943 Breast Neoplasms Genistein 10.3116873071 16541309 17200150
MESH:D001943 Breast Neoplasms kaempferol 10.3116756079
MESH:D001943 Breast Neoplasms Paclitaxel 10.3116273361 16115903 16244791 11325840 18323546 15136595 18234424 18223236
MESH:D001943 Breast Neoplasms Progesterone 10.3116175315 17614352 15562024
MESH:D001943 Breast Neoplasms Quercetin 10.3118628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 10.3120435547
MESH:D001943 Breast Neoplasms Tretinoin 10.3116443354 16166294 16873071
MESH:D001991 Bronchitis vanadium pentoxide 5.7717459161
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.1416813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9111589617
MESH:D002105 Cadmium Poisoning Quercetin 5.0816962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0116111702
MESH:D002276 Carcinoid Tumor Doxorubicin 10.8116051944
MESH:D002276 Carcinoid Tumor Fluorouracil 10.8116051944
MESH:D002277 Carcinoma Fluorouracil 6.9917121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 6.9916835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.6916168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 23.973084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 23.9715553829 15073043 16217749 11135700 14691202
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 23.9720101231 19519916 16502159 18393292 18494052 17428255 18978308 19539802 19107877 17055752 20214788 17978847 16540662 20514400 19208518 3084413 20727157 16288022 19919837 18785209 16569478 17173139 19383236 18506893 16830150 18210153 16698587 16807293 17162532 19052882 16328049 17138121 16935385 17761372 3581430 10672840 16779866 19171122 11831363 18788625 20084675 19701751 21159647 16878318 19418558 20935162 19335982 20512989 19822196 19394651 18665156 10737359 20524982 18056438 18691550 16681979 20007298 20432363 18971187
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 23.9718059187 16234567 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 23.9716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 23.9718930000 16332177 17971768 17045692 16799960 17088986
MESH:D006528 Carcinoma, Hepatocellular Genistein 23.9716924424
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 23.9716313753
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 23.9720007298 6705139 1701930 20935162 17173139
MESH:D006528 Carcinoma, Hepatocellular Quercetin 23.9712508355 19519916
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 23.971917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.5317123778
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.5117234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4119014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 9.6016201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 9.6018695887
MESH:D002292 Carcinoma, Renal Cell Vinblastine 9.601485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7212490120
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 12.726189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 12.7218986760 16757204 17066447 16280240
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 12.7218922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 12.7216051514 16096774
MESH:D002294 Carcinoma, Squamous Cell Zinc 12.7216543248
MESH:D006332 Cardiomegaly Quercetin 5.9219794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 5.9218670907 18850075 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2316952015 16455267 17928571 17308081 16651473 17382496 18627295 16612575 15811867 17974986 15792986 17519947 17351982 17924179 16278810 17007740 17329180 16242529 17131338 15476868 15505089 16269455 16109756 16364871 16731534
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.7816243910 17334414
MESH:D002318 Cardiovascular Diseases Genistein 14.8316332659
MESH:D002318 Cardiovascular Diseases Isoflavones 14.8317689850
MESH:D002318 Cardiovascular Diseases kaempferol 14.8316756079
MESH:D002318 Cardiovascular Diseases Zinc 14.8316936243
MESH:D002386 Cataract Acetaminophen 6.3010977129
MESH:D002386 Cataract Tretinoin 6.3017460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 13.3920889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.3912371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 13.397505956 2727394 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.3918566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.814080065
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.1416129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.0519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.0516835633
MESH:D002779 Cholestasis Cyclosporine 6.6519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 6.6515861022 16919318 17333356 11677210 17110522 16105132 17681005
MESH:D002822 Choriocarcinoma Tretinoin 4.6916461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.088697196 15340226 12621046 15668235 16354765
MESH:D002972 Cleft Palate Tretinoin 5.089407595
MESH:D003092 Colitis Tretinoin 3.2617035595
MESH:D003110 Colonic Neoplasms arsenite 9.9815037631
MESH:D003110 Colonic Neoplasms Fluorouracil 9.9817725105 16340194 17169374 16510598 17172411 18772588 17287894 15001691 17016597 17018589
MESH:D003110 Colonic Neoplasms Genistein 9.9817182828
MESH:D003110 Colonic Neoplasms polyphenols 9.9816293270
MESH:D003110 Colonic Neoplasms Quercetin 9.9816640504 11134977 17191121 15741050 19056647 17148506 19440933
MESH:D015179 Colorectal Neoplasms arsenic trioxide 11.7520501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 11.7518802399 18259882
MESH:D015179 Colorectal Neoplasms Fluorouracil 11.7516524972 17255274 18448328 14970324 17695437 18949393 20501625 16391804 18802399 17094418 18509181 18288408 17401013 17454858 17016601 18383874 17594712 16331619 15289873 16303861 16282729 15148649
MESH:D015179 Colorectal Neoplasms Isoflavones 11.7517116718
MESH:D015179 Colorectal Neoplasms Paclitaxel 11.7518802399
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 11.7515531428
MESH:D015179 Colorectal Neoplasms Quercetin 11.7518852136 18095365
MESH:D015179 Colorectal Neoplasms Vinblastine 11.7518802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.6817141729 14669216
MESH:D023903 Coronary Restenosis arsenic trioxide 3.7512609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.9110525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 4.9110048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 4.919142499 10589399 9211117 17551590 9224671 14991402 16925845 9664655 9125849 8800419
MESH:D019465 Craniofacial Abnormalities Zinc 4.9119302082
MESH:D007644 Darier Disease Fluorouracil 4.3416733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.6815213294
MESH:D003704 Dementia Polychlorinated Biphenyls 4.3016140633
MESH:D003920 Diabetes Mellitus Zinc 3.8216479319
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.3719496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.3320387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.3316647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.3317107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.0319279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.0517187935
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 10.3514986274 10774834 16227642 19370779 11834606 12392966 19416960 16109766 19739265 18713872 18071297 12594235 11461765 19164858 16781746 16081117 14725611 15619225 11421492 2444490 17522070 16393943 12958197 16177239 12153990 11739529 17906064 17562736 11529661 19085960 10915739 11743745 11287661 16485898 14550746 19420014 12705907 15968718 10663392 19923254 12540782
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 10.3519107877
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 10.3517416283
MESH:D056486 Drug-Induced Liver Injury polyphenols 10.3519370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 10.3520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6319426721
MESH:D004362 Drug Toxicity Doxorubicin 16.8918602426
MESH:D004362 Drug Toxicity Lamivudine 16.8915040536
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 16.8911462148
MESH:D004362 Drug Toxicity Zidovudine 16.8915040536
MESH:D004421 Dystonia Phenobarbital 3.591851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.6412711302 11000095
MESH:D004487 Edema Tetradecanoylphorbol Acetate 5.6411698051 9599246 15177302 8273558 7812673 8113982 16716910
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.4015322242 18230668 16714409
MESH:D004489 Edema, Cardiac Tretinoin 10.4018230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.6112538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 7.6117692515
MESH:D004714 Endometrial Hyperplasia Genistein 4.1316402032
MESH:D016889 Endometrial Neoplasms Doxorubicin 15.3017359293
MESH:D016889 Endometrial Neoplasms Estradiol 15.3019148513 11473722 18566989
MESH:D016889 Endometrial Neoplasms Genistein 15.3011473722
MESH:D016889 Endometrial Neoplasms Tretinoin 15.3016569247
MESH:D004715 Endometriosis Progesterone 7.6216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 7.629294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.6918037988
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.673659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.413922381 11558140
MESH:D004827 Epilepsy Phenobarbital 2.6520417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.166401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.817750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.573659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.6516302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.3720426865
MESH:D004938 Esophageal Neoplasms arsenic trioxide 12.3712903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 12.3715173087 16481741 16337965 16785472 17638652
MESH:D004938 Esophageal Neoplasms Paclitaxel 12.3716481741
MESH:D004938 Esophageal Neoplasms Zinc 12.3716543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 7.7011564622
MESH:D005124 Eye Abnormalities Tretinoin 7.709664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 25.4715073043
MESH:D005234 Fatty Liver arsenite 25.4718296743
MESH:D005234 Fatty Liver Cyclosporine 25.4719224547
MESH:D005234 Fatty Liver Diethylnitrosamine 25.4721071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 25.4715345470
MESH:D005234 Fatty Liver Zidovudine 25.4718299183
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0111858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.1319069698
MESH:D005355 Fibrosis arsenite 23.0518296743
MESH:D005355 Fibrosis Cyclosporine 23.0512168785 12639820
MESH:D005355 Fibrosis Quercetin 23.0519474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 23.0520067830
MESH:D005355 Fibrosis Tretinoin 23.0517994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8316904648
MESH:D005756 Gastritis Acetaminophen 9.6316983495
MESH:D005756 Gastritis Zinc 9.6317241300
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.768708960
MESH:D005909 Glioblastoma Doxorubicin 23.8417150277
MESH:D005909 Glioblastoma Genistein 23.8416598420
MESH:D005909 Glioblastoma Manganese 23.8417043766
MESH:D005909 Glioblastoma myricetin 23.8419804834
MESH:D005909 Glioblastoma Quercetin 23.8419804834
MESH:D005909 Glioblastoma Tretinoin 23.8417312396
MESH:D005910 Glioma Fluorouracil 5.5316145905
MESH:D005910 Glioma Quercetin 5.5317643826
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1310696789
MESH:D006130 Growth Disorders Zinc 3.6617217573
MESH:D006258 Head and Neck Neoplasms Doxorubicin 11.1715692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 11.1715162350 18337622 15102660
MESH:D006258 Head and Neck Neoplasms Tretinoin 11.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.6916084493
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 5.7011294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 5.7014991402 9664655
MESH:D006331 Heart Diseases Doxorubicin 3.1716879835 17888722 17875725 16244371 14766674 12587719 18006777 16144979 16495754 16330681 16244372 18674790 16707910
MESH:D006333 Heart Failure Doxorubicin 6.4817481944
MESH:D006333 Heart Failure Zinc 6.4817162251
MESH:D006335 Heart Injuries Zinc 5.3117074742
MESH:D016481 Helicobacter Infections Zinc 4.1117241300
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5015692506
MESH:D006402 Hematologic Diseases Zidovudine 4.2912579204
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 3.9715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9311000095
MESH:D006509 Hepatitis B Lamivudine 4.6917703166
MESH:D019694 Hepatitis B, Chronic Lamivudine 4.6916476009 15631357 12044531 15309715 15274664
MESH:D006527 Hepatolenticular Degeneration Zinc 4.2517276780
MESH:D006529 Hepatomegaly Phenobarbital 6.9816109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 6.9816120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.5715709030
MESH:D015658 HIV Infections Lamivudine 6.2211141242 9296927 17530837 20032539
MESH:D015658 HIV Infections Zidovudine 6.2211141242 11698656 17358032 11363243 20032539
MESH:D006689 Hodgkin Disease Doxorubicin 6.5518501091 15147373 17606976
MESH:D006689 Hodgkin Disease Vinblastine 6.5518501091 18180244
MESH:D019584 Hot Flashes Estradiol 8.8817088409
MESH:D019584 Hot Flashes Isoflavones 8.8814716179 17290160
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.5815340226 16354765 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 6.4416870215
MESH:D006930 Hyperalgesia Tretinoin 6.4416870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.1216778211
MESH:D006943 Hyperglycemia kaempferol 8.6018262572
MESH:D006943 Hyperglycemia Quercetin 8.6018262572 11834736
MESH:D006973 Hypertension Cyclosporine 7.4610903974
MESH:D006973 Hypertension Quercetin 7.4618356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 7.4618850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.3716945680 16569931
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 3.9615869954
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.1817937319
MESH:D007249 Inflammation Diethylnitrosamine 13.2218785209
MESH:D007249 Inflammation polyphenols 13.2216366677
MESH:D007249 Inflammation Progesterone 13.2215869954
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 13.2212200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 13.227562506 8273558 11698051 7812673 15177302
MESH:D007251 Influenza, Human Quercetin 4.0516624496
MESH:D007333 Insulin Resistance bisphenol A 6.4316393666
MESH:D007333 Insulin Resistance Estradiol 6.4316627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.3317994277
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.1910783313
MESH:D007511 Ischemia Zinc 4.1916584753
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 8.5816580747
MESH:D007569 Jaw Abnormalities Tretinoin 8.5815992940 17551590
MESH:D007627 Keloid Quercetin 4.5117086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 3.9815604871
MESH:D007674 Kidney Diseases Acetaminophen 24.6715629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 24.6715369732
MESH:D007674 Kidney Diseases Cyclosporine 24.6710903974 8314463 18776723
MESH:D007674 Kidney Diseases Doxorubicin 24.6715369732 15699352 16775033
MESH:D007674 Kidney Diseases Estradiol 24.6715618244
MESH:D007674 Kidney Diseases Quercetin 24.6716962696
MESH:D007674 Kidney Diseases Zinc 24.6716960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 8.8316707910
MESH:D007676 Kidney Failure, Chronic Zinc 8.8316518626
MESH:D007680 Kidney Neoplasms Cyclosporine 14.7712371664
MESH:D007680 Kidney Neoplasms Estradiol 14.7715610895
MESH:D007680 Kidney Neoplasms Fluorouracil 14.7716985049
MESH:D007680 Kidney Neoplasms Zidovudine 14.7712579204
MESH:D007938 Leukemia arsenic trioxide 17.1615070760
MESH:D007938 Leukemia Genistein 17.1618980019 17468513
MESH:D007938 Leukemia kaempferol 17.1617468513
MESH:D007938 Leukemia Quercetin 17.1617468513
MESH:D007938 Leukemia Tretinoin 17.1617143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.6916085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 8.4917077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Zidovudine 8.4920370541
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 10.2416972261
MESH:D007948 Leukemia, Monocytic, Acute U 0126 10.2416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.0914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 8.1319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.1316482212 16932348 19285840
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.5516467208 17050201 20471514 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.5516294345 19850784 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 11.0717107899 16966277 9834237 16823087 19035177 17649720 19642359 11161223 15213294 19225113 19075265 17869043 11468182 12712474 16891316 16331271 16112521 15748426 17712046 15336539 15622746 17217047 12018890 12679006 16330433
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 11.0716766008
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 11.0717339181 19035177 17361223 15748426 16891316 16331271 17712046 19029980 9834237 17301526 19075265 17217047 17294898 17107899 16823087 19225113 17506722 16935935 17649720 16766008 12679006 19642359 16788101 17368321 16140955
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9216882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 2.989224671
MESH:D008080 Liposarcoma Paclitaxel 4.4017353645
MESH:D008103 Liver Cirrhosis arsenite 9.5818296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 9.5820032147 18665156 19638242 18407596 18522880
MESH:D008103 Liver Cirrhosis Phenobarbital 9.5821047994
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 7.8216595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 7.8214659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 7.8217823541
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 7.8212741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 7.8212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 7.8218397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 8.2512969438 11587558 19460945 16611625 19014921 16610002 19784758 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 8.2517034775
MESH:D008107 Liver Diseases Phenobarbital 8.2519363144
MESH:D008107 Liver Diseases polyphenols 8.2516698588
MESH:D017114 Liver Failure, Acute Acetaminophen 2.8416871587 17185352
MESH:D008113 Liver Neoplasms arsenic trioxide 15.4914682389
MESH:D008113 Liver Neoplasms Diethylnitrosamine 15.4919499222 20101389 19256749 19294768 19426721 19996281 21278145 19254457 12112319 18977376 10737359 18648771 18644402 19255062 20137499 15885732 9163691 20583210 19812893 21167192 18754104 15175105 12771043 19427195 19690152 19073162 21047994 21071580 20452335 2422723 20405173 19642983 19638242 20492335 19833225 18978307 20118626 19551842 20434301 2862719 19850985 20501860 16942905 19090486
MESH:D008113 Liver Neoplasms Fluorouracil 15.4915113037 16603448 17045692 18383874
MESH:D008113 Liver Neoplasms Phenobarbital 15.4915975961 8742319 19812893 21047994 19073162 19482888
MESH:D008113 Liver Neoplasms Quercetin 15.4918980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 15.4916984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 23.7920377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 23.7921159647 19539802 16842330 19009564 18308698 18079962 18282651 16267830 18253720 18775883 18164116 18544905 2563599 3124819 17942915 18093689 17174075 17854601 19126423 19004024 9362446 19519916
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 23.7917085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 23.792563599 1399818 18308698 6150874 17172636
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 23.791423854
MESH:D008114 Liver Neoplasms, Experimental Quercetin 23.7919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 23.7912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.0015213294
MESH:D008175 Lung Neoplasms arsenic trioxide 16.3811798837 19825857
MESH:D008175 Lung Neoplasms arsenite 16.3816809336
MESH:D008175 Lung Neoplasms Diethylnitrosamine 16.3821163286 6695378 20512841 20970405
MESH:D008175 Lung Neoplasms Doxorubicin 16.3817418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 16.3815246190
MESH:D008175 Lung Neoplasms Quercetin 16.3816280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 16.3819555203 11884234
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 16.3811807781
MESH:D008175 Lung Neoplasms vanadium pentoxide 16.3812376484
MESH:D008175 Lung Neoplasms Zidovudine 16.3818800350
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.3415086387
MESH:D008223 Lymphoma Doxorubicin 3.1416098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 7.7317654614
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 7.7314749477
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.1215621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 19.7015458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 19.7011807958 11408345 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 19.7014578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 19.7017203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 19.708985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 19.7012773700
MESH:D020149 Manganese Poisoning Estradiol 11.4619453300
MESH:D020149 Manganese Poisoning Manganese 11.4619453300 16568477 16551646
MESH:D008527 Medulloblastoma Tretinoin 2.5917453147
MESH:D008545 Melanoma Doxorubicin 6.5616827129
MESH:D008545 Melanoma Paclitaxel 6.5612040289 12025231 16342250
MESH:D008545 Melanoma Tretinoin 6.5616752155
MESH:D008545 Melanoma Vinblastine 6.5615577320 17761969 18332650 18505091 18176117 16432458 16248763 16809738 12374674 15577323
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1219513568
MESH:D008591 Meningomyelocele Tretinoin 3.9816940565
MESH:D008654 Mesothelioma Doxorubicin 2.8717638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3216801185
MESH:D048629 Micronuclei, Chromosome-Defective Zidovudine 5.3717358032
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.0915792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.2816757204 18986760
MESH:D009069 Movement Disorders Manganese 4.5916551646
MESH:D052016 Mucositis Doxorubicin 4.3417415656
MESH:D009101 Multiple Myeloma arsenic trioxide 6.4215949261 14977855 19549372 19417148 11468182
MESH:D009101 Multiple Myeloma Paclitaxel 6.4214749477
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 6.4916882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 6.4917596541
MESH:D009203 Myocardial Infarction Doxorubicin 8.4019429709 15857846
MESH:D009203 Myocardial Infarction Genistein 8.4017141266
MESH:D009203 Myocardial Infarction Quercetin 8.4019595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.6612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.2616810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.2617141266
MESH:D015428 Myocardial Reperfusion Injury Quercetin 12.2619207477
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0217484760
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5316624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 8.463581430 9029167
MESH:D009362 Neoplasm Metastasis Doxorubicin 8.4618259882
MESH:D009362 Neoplasm Metastasis Paclitaxel 8.4615867366
MESH:D009369 Neoplasms Fluorouracil 6.9818600527 18239605 16928823
MESH:D009369 Neoplasms Quercetin 6.9815185748
MESH:D009369 Neoplasms Tretinoin 6.9816946489 16594593
MESH:D009389 Neovascularization, Pathologic arsenite 8.6415738583
MESH:D009389 Neovascularization, Pathologic Estradiol 8.6417289903
MESH:D009401 Nephrosis Doxorubicin 4.3216636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 3.9817954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.0318481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.0315640375 16889571
MESH:D009410 Nerve Degeneration Manganese 3.9316551646
MESH:D009421 Nervous System Malformations bisphenol A 26.1716427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 26.1716427766 11399458
MESH:D009421 Nervous System Malformations Genistein 26.1716427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 26.1714600291
MESH:D009421 Nervous System Malformations Tretinoin 26.179125849
MESH:D009436 Neural Tube Defects arsenic trioxide 6.2910525206
MESH:D009436 Neural Tube Defects Tretinoin 6.299142499
MESH:D009447 Neuroblastoma Doxorubicin 3.0215555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 6.9518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 6.9520387270
MESH:D020078 Neurogenic Inflammation Quercetin 3.9417929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.6520387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.1316436463
MESH:D009503 Neutropenia Vinblastine 4.1517378895
MESH:D010014 Osteolysis Paclitaxel 4.5315867366
MESH:D010018 Osteomalacia Phenobarbital 3.9117016548
MESH:D010024 Osteoporosis Genistein 10.5019401787
MESH:D010024 Osteoporosis Isoflavones 10.5016562857
MESH:D010024 Osteoporosis kaempferol 10.5016756079
MESH:D015663 Osteoporosis, Postmenopausal Genistein 8.7516169203
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 8.7519495926
MESH:D012516 Osteosarcoma Doxorubicin 3.7515930896
MESH:D010049 Ovarian Diseases bisphenol A 4.5311985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 28.2712452020 19769630 16624393
MESH:D010051 Ovarian Neoplasms Estradiol 28.2719401270
MESH:D010051 Ovarian Neoplasms Genistein 28.2719005980
MESH:D010051 Ovarian Neoplasms Luteolin 28.2719005980
MESH:D010051 Ovarian Neoplasms Paclitaxel 28.2711161223
MESH:D010051 Ovarian Neoplasms Progesterone 28.2716525653 17393432
MESH:D010051 Ovarian Neoplasms Quercetin 28.2719005980
MESH:D010051 Ovarian Neoplasms Tretinoin 28.2716936753
MESH:D010051 Ovarian Neoplasms U 0126 28.2716211241
MESH:D010146 Pain Acetaminophen 5.3816870215
MESH:D010146 Pain Tretinoin 5.3816870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 22.0715580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 22.0716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 22.0716929163 16500647 19003803 15113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 22.0716965848
MESH:D010190 Pancreatic Neoplasms Quercetin 22.0716965848
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 22.0715976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 22.0715976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.2711578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.8518922899 12065085 8330346 18404319
MESH:D010235 Paraganglioma arsenic trioxide 3.7419927285
MESH:D010300 Parkinson Disease Manganese 5.3211181820
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 5.3216702228
MESH:D020734 Parkinsonian Disorders Manganese 4.0816140633
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.7812520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.6917983394
MESH:D010997 Pleural Neoplasms Doxorubicin 4.6917638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1318163543
MESH:D011230 Precancerous Conditions Cyclosporine 18.7412371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 18.742563599
MESH:D011230 Precancerous Conditions Phenobarbital 18.742563599
MESH:D011230 Precancerous Conditions Quercetin 18.7419056647
MESH:D011225 Pre-Eclampsia Zinc 3.8217114810
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 8.0010548101
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.0011118676 11896295 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.2020887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.2020887781
MESH:D011471 Prostatic Neoplasms Apigenin 5.5117132221
MESH:D011471 Prostatic Neoplasms arsenic trioxide 5.5119131511
MESH:D011471 Prostatic Neoplasms bicalutamide 5.5119011039 18487222 17914592 19240160 15638997
MESH:D011471 Prostatic Neoplasms bisphenol A 5.5116740699
MESH:D011471 Prostatic Neoplasms Doxorubicin 5.5116868541 16888761 18437689 15749863 15897917 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 5.5116740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 5.5119082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 5.5115256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms Isoflavones 5.5117571952 17374662 16365062 17219775
MESH:D011471 Prostatic Neoplasms Paclitaxel 5.5117136230 17172428 16729912 16356831
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 5.5115721890
MESH:D011471 Prostatic Neoplasms Quercetin 5.5114715546 17292933
MESH:D011471 Prostatic Neoplasms Zinc 5.5116606632 12429649 16700911 16517595
MESH:D011507 Proteinuria Tretinoin 3.1916636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.8615861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.0312752131
MESH:D011565 Psoriasis Cyclosporine 2.0616882103
MESH:D011625 Pterygium Tretinoin 4.3416723453
MESH:D011629 Puberty, Precocious bisphenol A 4.3310548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.6316160472 18286688 18722050 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 3.7817922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4118990726
MESH:D012162 Retinal Degeneration Zinc 3.7916584753
MESH:D012206 Rhabdomyolysis Lamivudine 5.089296927
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.6816283617 16116481
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.6818045962
MESH:D012509 Sarcoma Doxorubicin 3.6017710206 15625365 16767912 18313854 17203757 15675481
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 8.8516646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 8.8514601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3417846226
MESH:D012554 Schistosomiasis japonica Quercetin 5.0816862918
MESH:D012640 Seizures Phenobarbital 2.403137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 4.376407741
MESH:D012878 Skin Neoplasms Doxorubicin 15.4915692506
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 15.498532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 15.4916192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 15.4912065085 11807781 8985016 8330346 18404319
MESH:D012878 Skin Neoplasms Tretinoin 15.4916467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1217203757 15625365 16767912
MESH:D013088 Spermatocele Ethinyl Estradiol 3.4816709447
MESH:D013119 Spinal Cord Injuries Progesterone 3.8316503802 15862959
MESH:D013274 Stomach Neoplasms arsenic trioxide 7.5417007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 7.5418456281
MESH:D013274 Stomach Neoplasms Fluorouracil 7.5418567086 18396642 17498489 15786421 19015929 19084572 16951190 17522103 16424979 17172411
MESH:D013274 Stomach Neoplasms Paclitaxel 7.5418396642 18506536
MESH:D013274 Stomach Neoplasms Tretinoin 7.5417261132
MESH:D013274 Stomach Neoplasms Zidovudine 7.5417696246
MESH:D019966 Substance-Related Disorders bisphenol A 3.5316684133 16045194
MESH:D024801 Tauopathies Paclitaxel 4.3616930453
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.7917997062
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.7715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4412697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 18.8019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 18.807505956
MESH:D013964 Thyroid Neoplasms Doxorubicin 18.8016010429 17909728
MESH:D013964 Thyroid Neoplasms Phenobarbital 18.801399818
MESH:D013964 Thyroid Neoplasms Tretinoin 18.8016026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.2219048282
MESH:D014062 Tongue Neoplasms Fluorouracil 14.3316280240
MESH:D014062 Tongue Neoplasms Tretinoin 14.3316051514
MESH:D014062 Tongue Neoplasms Zinc 14.3316543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.5115213294
MESH:D014376 Tuberculosis Tretinoin 2.9416040207
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.3020435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 7.3017653716
MESH:D001749 Urinary Bladder Neoplasms Quercetin 7.3016720314
MESH:D014581 Urticaria Acetaminophen 2.5610982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 8.1416803524
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.1416129372
MESH:D014591 Uterine Diseases bisphenol A 4.5414652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.8714692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.1516752155
MESH:D014605 Uveitis Cyclosporine 3.521336536
MESH:D014625 Vaginal Neoplasms Vinblastine 9.8915577323
MESH:D014625 Vaginal Neoplasms Zidovudine 9.8912579204
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1315869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.7817638931 17334414 16364871 17678736
MESH:D014820 Vitiligo Tretinoin 3.6316761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.7815886252
MESH:D009396 Wilms Tumor Tretinoin 3.5816287080
MESH:D014985 Xerophthalmia Cyclosporine 3.9817120751
Pathway ID Pathway Name
KEGG:04110 Cell cycle
REACT:152 Cell Cycle, Mitotic
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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