Annotation Detail for B3GNT3
Basic Information
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| Gene Symbol: | B3GNT3 ( B3GAL-T8,B3GN-T3,B3GNT-3,HP10328,TMEM3,beta3Gn-T3 ) |
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| Gene Full Name: | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
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| Band: | 19p13.11 |
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| Quick Links | Entrez ID:10331; OMIM: 605863; Uniprot ID:B3GN3_HUMAN; ENSEMBL ID: ENSG00000179913; HGNC ID: 13528 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00601 | Glycosphingolipid biosynthesis - lacto and neolacto series |
| hsa01100 | Metabolic pathways |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol results in increased expression of B3GNT3 mRNA | increases expression | 17557909
|
| D008727 |
Methotrexate |
B3GNT3 protein affects the susceptibility to Methotrexate | affects response to substance | 16217747
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Methotrexate |
5.13 | 12039119 |
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
5.01 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.90 | 14692618 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.23 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.93 | 15885639 |
| MESH:D001172 |
Arthritis, Rheumatoid |
|
Methotrexate |
3.18 | 17286800 |
| MESH:D001943 |
Breast Neoplasms |
|
Methotrexate |
3.06 | 16978400 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.24 | 17110522 16105132 17333356 15861022 17681005 11677210 16919318 |
| MESH:D019465 |
Craniofacial Abnormalities |
|
Methotrexate |
2.67 | 9562676 12039119 |
| MESH:D003550 |
Cystic Fibrosis |
|
Methotrexate |
4.74 | 19747007 |
| MESH:D003882 |
Dermatomyositis |
|
Methotrexate |
5.80 | 20191521 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.86 | 12538720 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.36 | 15345470 |
| MESH:D006086 |
Graft vs Host Disease |
|
Methotrexate |
5.91 | 16518429 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.57 | 16945680 16569931 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
4.07 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.79 | 17937319 |
| MESH:D007805 |
Language Development Disorders |
|
Methotrexate |
5.71 | 9562676 |
| MESH:D008103 |
Liver Cirrhosis |
|
Methotrexate |
3.93 | 14986274 |
| MESH:D017563 |
Lung Diseases, Interstitial |
|
Methotrexate |
6.09 | 18516814 |
| MESH:D008223 |
Lymphoma |
|
Methotrexate |
4.29 | 17352296 |
| MESH:D052016 |
Mucositis |
|
Methotrexate |
6.17 | 17488658 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.29 | 11578682 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
4.20 | 16919318 15861022 |
| MESH:D011565 |
Psoriasis |
|
Methotrexate |
3.56 | 17410198 |
| MESH:D051437 |
Renal Insufficiency |
|
Methotrexate |
5.47 | 17352296 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
5.01 | 16709447 |
| MESH:D013576 |
Syndactyly |
|
Methotrexate |
5.71 | 9562676 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.23 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.62 | 15669648 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.97 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
4.09 | 14671159 15869587 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:00601 |
Glycosphingolipid biosynthesis - lacto and neolacto series |
| KEGG:01100 |
Metabolic pathways |
Related Diseases/Disorders