AutismKB 2.0

Annotation Detail for BTN2A2


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Basic Information Top
Gene Symbol:BTN2A2 ( BT2.2,BTF2,FLJ41908 )
Gene Full Name: butyrophilin, subfamily 2, member A2
Band: 6p22.2
Quick LinksEntrez ID:10385; OMIM: 613591; Uniprot ID:BT2A2_HUMAN; ENSEMBL ID: ENSG00000124508; HGNC ID: 1137
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C017947 sodium arsenite sodium arsenite results in increased expression of BTN2A2 mRNAincreases expression 17879257
D014212 Tretinoin Tretinoin results in increased expression of BTN2A2 mRNAincreases expression 16788091
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.7715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.9716712894 17306315
MESH:D000505 Alopecia Tretinoin 4.0215955085
MESH:D001169 Arthritis, Experimental Tretinoin 3.3516412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.3416292516
MESH:D001249 Asthma Tretinoin 2.4516456186
MESH:D001471 Barrett Esophagus Tretinoin 5.0816935849
MESH:D001778 Blood Coagulation Disorders Tretinoin 4.1616197459 16206674
MESH:D001943 Breast Neoplasms Tretinoin 2.2216873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 5.4816813970
MESH:D018236 Carcinoma, Embryonal Tretinoin 6.2316168501
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.2617306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 3.261917145
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 5.0518572023
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 5.0516096774 16051514
MESH:D002386 Cataract Tretinoin 3.3417460283
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.3119524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 5.4816129372
MESH:D002822 Choriocarcinoma Tretinoin 6.2316461808
MESH:D002972 Cleft Palate Tretinoin 2.839407595
MESH:D003092 Colitis Tretinoin 4.4717035595
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.839125849 9211117 14991402 9224671 10589399 9142499 8800419 16925845 9664655 17551590
MESH:D004489 Edema, Cardiac Tretinoin 5.5418230668
MESH:D016889 Endometrial Neoplasms Tretinoin 3.4016569247
MESH:D005124 Eye Abnormalities Tretinoin 3.949664655 16938888
MESH:D005355 Fibrosis Tretinoin 4.2717994277
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.5716452187
MESH:D005909 Glioblastoma Tretinoin 3.3017312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.4916096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 6.2316084493
MESH:D006330 Heart Defects, Congenital Tretinoin 3.1114991402 9664655
MESH:D006689 Hodgkin Disease sodium arsenite 3.6212676792
MESH:D006930 Hyperalgesia Tretinoin 3.6216870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 5.3316778211
MESH:D007248 Infertility, Male sodium arsenite 3.2915346721 12646999
MESH:D007410 Intestinal Diseases Tretinoin 4.5317994277
MESH:D007569 Jaw Abnormalities Tretinoin 4.4515992940 17551590
MESH:D007674 Kidney Diseases sodium arsenite 3.0420008137
MESH:D007938 Leukemia Tretinoin 2.9717143497
MESH:D007951 Leukemia, Myeloid Tretinoin 4.2516482212 19285840 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.1316294345 17596541 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.4519225113 16823087 17301526 17294898 19029980 19075265 16766008 17506722 16935935 17361223 16140955 16788101 16331271 17649720 15748426 12679006 19642359 16891316 9834237 17339181 19035177 17368321 17107899 17712046 17217047
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.659224671
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 1.8116248980 18397230
MESH:D008113 Liver Neoplasms sodium arsenite 2.5115276417 16712894
MESH:D008171 Lung Diseases sodium arsenite 3.4819095001
MESH:D008175 Lung Neoplasms sodium arsenite 1.9015276417 17077188 17306315 19931552 16712894
MESH:D008527 Medulloblastoma Tretinoin 2.9317453147
MESH:D008545 Melanoma sodium arsenite 3.5416487513 19082730
MESH:D008545 Melanoma Tretinoin 3.5416752155
MESH:D008591 Meningomyelocele Tretinoin 5.1916940565
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.3217596541
MESH:D009369 Neoplasms sodium arsenite 5.8011559025
MESH:D009369 Neoplasms Tretinoin 5.8016946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.4320056578
MESH:D009421 Nervous System Malformations Tretinoin 4.459125849
MESH:D009436 Neural Tube Defects sodium arsenite 8.3112854658
MESH:D009436 Neural Tube Defects Tretinoin 8.319142499
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.2815276417 17306315
MESH:D010051 Ovarian Neoplasms Tretinoin 5.2816936753
MESH:D010146 Pain Tretinoin 3.3316870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.5915976015
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2316039940
MESH:D011507 Proteinuria Tretinoin 4.2116636307
MESH:D011625 Pterygium Tretinoin 5.6816723453
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.7116116481 16283617
MESH:D012878 Skin Neoplasms sodium arsenite 6.4418572023 19524636
MESH:D012878 Skin Neoplasms Tretinoin 6.4416467112
MESH:D016135 Spinal Dysraphism sodium arsenite 4.1812854658
MESH:D013274 Stomach Neoplasms Tretinoin 1.8017261132
MESH:D013964 Thyroid Neoplasms Tretinoin 3.4016026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 4.2916051514
MESH:D014376 Tuberculosis Tretinoin 3.5016040207
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 2.6516712894 16452187 11723127 17306315
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 11.1411813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 11.1416129372
MESH:D014604 Uveal Neoplasms Tretinoin 5.6816752155
MESH:D014652 Vascular Diseases sodium arsenite 5.3117056641
MESH:D014820 Vitiligo Tretinoin 4.7316761959
MESH:D009396 Wilms Tumor Tretinoin 4.4416287080
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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