AutismKB 2.0

Annotation Detail for RBM14


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Basic Information Top
Gene Symbol:RBM14 ( COAA,DKFZp779J0927,MGC15912,MGC31756,PSP2,SIP,SYTIP1,TMEM137 )
Gene Full Name: RNA binding motif protein 14
Band: 11q13.2
Quick LinksEntrez ID:10432; OMIM: 612409; Uniprot ID:RBM14_HUMAN; ENSEMBL ID: ENSG00000173933,ENSG00000239306; HGNC ID: 14219
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of RBM14 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of RBM14 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RBM14 mRNAaffects expression 16483693
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of RBM14 mRNAaffects expression 17331233
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of RBM14 mRNAdecreases expression 19150397
20382639
D016572 Cyclosporine Cyclosporine results in decreased expression of RBM14 mRNAdecreases expression 20106945
D004958 Estradiol Estradiol results in decreased expression of RBM14 mRNAdecreases expression 20068009
D005472 Fluorouracil Fluorouracil results in increased expression of RBM14 mRNAincreases expression 16557594
D012643 Selenium Selenium results in increased expression of RBM14 mRNAincreases expression 19244175
C025643 vinclozolin vinclozolin affects the expression of RBM14 mRNAaffects expression 19015723
D014810 Vitamin E Vitamin E results in increased expression of RBM14 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.7518287403
MESH:D000230 Adenocarcinoma Estradiol 4.5511473722
MESH:D000230 Adenocarcinoma Fluorouracil 4.5517638652
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.833712494
MESH:D000740 Anemia Fluorouracil 3.8416511603 17963324 15504547
MESH:D000799 Angioedema Acetaminophen 4.0610982225
MESH:D001008 Anxiety Disorders vinclozolin 3.7519015723
MESH:D001321 Autistic Disorder Acetaminophen 1.4118445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.241440618 11289319
MESH:D001943 Breast Neoplasms Estradiol 2.2018497071 17289903 17018787 19861407 14630087 17261762 16675129 12948864
MESH:D001943 Breast Neoplasms Fluorouracil 2.2018608205 16110121 16595493 19217205 15136595 18357371 16557594
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6616111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1116050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.8916051944
MESH:D002277 Carcinoma Fluorouracil 3.6817121937
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 6.723581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.723084413
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.7216924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 6.7216799960 17088986 16332177 17045692 18930000 17971768
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.697296757
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.6918695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5216280240 16757204 17066447 18986760
MESH:D002386 Cataract Acetaminophen 2.6610977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 16.807505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 16.8020889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 16.8012371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 16.8018566989
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.2219486331 9022650
MESH:D002779 Cholestasis Cyclosporine 8.2219486331
MESH:D003092 Colitis Selenium 3.9517936198
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2517725105 17018589 15001691 17172411 16510598 17016597 18772588 17287894 17169374 16340194
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0017401013 20501625 18288408 16524972 14970324 16303861 15289873 16331619 18383874 17454858 17016601 18509181 16391804 18802399 17094418 18448328 17255274 16282729 17594712 17695437 15148649 18949393
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003456 Cryptorchidism vinclozolin 4.5014966744
MESH:D007644 Darier Disease Fluorouracil 4.9916733453
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.9712868966 11906362 8156756 11298694 18759878 8970840 2524372 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.642952479 3621924
MESH:D003928 Diabetic Nephropathies Estradiol 3.5419279558
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 6.429653073 7440962 6679447 1440618 8291058 16192314 18692083 18289764 9022650 6482804 9328219 18648102 11289319
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.4218071297 15968718 11739529 19739265 12540782 15619225 11529661 16081117 11743745 11421492 18713872 19085960 19416960 16227642 16393943 19420014 2444490 14986274 10663392 10915739 17562736 16177239 12594235 17522070 16485898 11287661 19370779 10774834 14725611 17906064 11461765 11834606 16781746 12958197 14550746 16109766 12705907 12153990 19923254 12392966 19164858
MESH:D056486 Drug-Induced Liver Injury Selenium 6.4215131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.3219426721
MESH:C538011 Eales disease Vitamin E 4.929068938
MESH:D016889 Endometrial Neoplasms Estradiol 3.0711473722 19148513 18566989
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.433581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4320426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 7.4316337965 16481741 15173087 17638652 16785472
MESH:D005234 Fatty Liver Cyclosporine 2.9919224547
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.246705139
MESH:D005355 Fibrosis Cyclosporine 3.3212639820 12168785
MESH:D005756 Gastritis Acetaminophen 3.8916983495
MESH:D030342 Genetic Diseases, Inborn vinclozolin 5.1316973722
MESH:D005832 Genital Diseases, Male vinclozolin 5.5216417039
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.418708960
MESH:D005910 Glioma Fluorouracil 2.9216145905
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.197505956
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.4815162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0516080930
MESH:D006333 Heart Failure Selenium 3.1517162251
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.6215720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.676705139
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7416863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.2515709030
MESH:D019584 Hot Flashes Estradiol 10.7917088409
MESH:D019584 Hot Flashes Vitamin E 10.7914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.8116870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.1115034207
MESH:D006973 Hypertension Cyclosporine 2.1410903974
MESH:D007248 Infertility, Male vinclozolin 3.1316467254
MESH:D007251 Influenza, Human Selenium 11.7016624496
MESH:D007251 Influenza, Human Vitamin E 11.7016624496
MESH:D007333 Insulin Resistance Estradiol 3.0516627594 16393666
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.249022650 8074119
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.6615604871
MESH:D007674 Kidney Diseases Acetaminophen 15.0512587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 15.058314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 15.0515618244
MESH:D007674 Kidney Diseases Vitamin E 15.0512488133
MESH:D007676 Kidney Failure, Chronic Selenium 4.0216518626
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 18.766582329
MESH:D007680 Kidney Neoplasms Cyclosporine 18.7612371664
MESH:D007680 Kidney Neoplasms Estradiol 18.7615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 18.7616985049
MESH:D007984 Leydig Cell Tumor vinclozolin 4.9316417039
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2815034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.5414659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.5416169303
MESH:D008107 Liver Diseases Acetaminophen 1.6619784758 19460945 12969438 16610002 11587558 12587719 19014921 16611625
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3717185352 16871587
MESH:D008113 Liver Neoplasms Fluorouracil 2.5315113037 16603448 18383874 17045692
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.616587162 1399818 598648 3712494
MESH:D008171 Lung Diseases Vitamin E 3.2716863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.2017365036
MESH:D008175 Lung Neoplasms Fluorouracil 2.6215246190
MESH:D008175 Lung Neoplasms Vitamin E 2.6211062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.9915086387
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.3116891317 17203775 11807958 11408345
MESH:D008325 Mammary Neoplasms, Experimental Selenium 6.3115318939
MESH:D020149 Manganese Poisoning Estradiol 4.7019453300
MESH:D008546 Melanoma, Experimental Acetaminophen 3.7419513568
MESH:D008654 Mesothelioma Asbestos, Crocidolite 6.5016166281 16966607 18303189
MESH:D008654 Mesothelioma Selenium 6.5015107826
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.0116801185
MESH:D009062 Mouth Neoplasms Fluorouracil 3.7418986760 16757204
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3916810080
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.523581430
MESH:D009369 Neoplasms Fluorouracil 2.6716928823 18239605 18600527
MESH:D009389 Neovascularization, Pathologic Estradiol 3.9317289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.6617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.4119348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 3.8116427766 11399458
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.006679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.9918514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.5316436463
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.556482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.243988306
MESH:D010051 Ovarian Neoplasms Estradiol 2.2519401270
MESH:D010146 Pain Acetaminophen 2.5016870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7115113037 16929163 16500647 19003803
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.667296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.696228378
MESH:D010954 Plasmacytoma Selenium 5.1115087411
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.0710923243
MESH:D011230 Precancerous Conditions Cyclosporine 3.3512371664
MESH:D011297 Prenatal Exposure Delayed Effects vinclozolin 4.0918042343 18220299 19015723
MESH:D011469 Prostatic Diseases vinclozolin 5.1318220299
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.0220887781
MESH:D011471 Prostatic Neoplasms Estradiol 2.5616740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.5618626508 19082440
MESH:D011471 Prostatic Neoplasms Vitamin E 2.5615084515
MESH:D011472 Prostatitis vinclozolin 5.1318629315
MESH:D011565 Psoriasis Cyclosporine 2.2716882103
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 3.0715814490 17322281 17975199 17365031
MESH:D012004 Rectal Neoplasms Fluorouracil 4.1418722050 16160472 18286688 15538739
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.483692021
MESH:D012871 Skin Diseases Vitamin E 2.4718709164
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0018396642 16424979 17522103 19015929 18567086 17172411 17498489 16951190 15786421 19084572
MESH:D020521 Stroke Vitamin E 3.6316517955
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 2.993712494 1399818 6587162 6582329 7505956
MESH:D013978 Tibial Fractures Estradiol 4.9019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.1216280240
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.328074119
MESH:D014581 Urticaria Acetaminophen 3.1210982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.0116803524
MESH:D014605 Uveitis Cyclosporine 4.201336536
MESH:D014985 Xerophthalmia Cyclosporine 4.6617120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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