AutismKB 2.0

Annotation Detail for OLFM1


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Basic Information Top
Gene Symbol:OLFM1 ( AMY,NOE1,NOELIN1,OlfA )
Gene Full Name: olfactomedin 1
Band: 9q34.3
Quick LinksEntrez ID:10439; OMIM: 605366; Uniprot ID:NOE1_HUMAN; ENSEMBL ID: ENSG00000130558; HGNC ID: 17187
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of OLFM1 mRNAincreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of OLFM1 mRNAdecreases expression 20406850
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of OLFM1 mRNAincreases expression 16788091
D000643 Ammonium Chloride Ammonium Chloride affects the expression of OLFM1 mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of OLFM1 mRNAincreases expression 20713471
C006780 bisphenol A bisphenol A results in increased expression of OLFM1 mRNAincreases expression 16474171
19371625
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of OLFM1 mRNAincreases expression 17942915
D004052 Diethylnitrosamine MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OLFM1 mRNA]decreases reaction|increases expression 17942915
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of OLFM1 mRNAincreases expression 19371625
D004958 Estradiol Estradiol affects the expression of OLFM1 mRNAaffects expression 14699072
D004958 Estradiol Estradiol results in increased expression of OLFM1 mRNAincreases expression 16474171
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of OLFM1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of OLFM1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of OLFM1 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of OLFM1 mRNAdecreases expression 12075121
D015025 Zearalenone Zearalenone results in increased expression of OLFM1 mRNAincreases expression 19371625
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of OLFM1 mRNAincreases expression 20713471
D005472 Fluorouracil Fluorouracil results in increased expression of OLFM1 proteinincreases expression 15352031
D005472 Fluorouracil OLFM1 protein affects the susceptibility to Fluorouracilaffects response to substance 15352031
D019833 Genistein Genistein results in increased expression of OLFM1 mRNAincreases expression 16474171
19371625
D008345 Manganese Manganese results in increased expression of OLFM1 mRNAincreases expression 17175027
C025340 manganese chloride manganese chloride results in increased expression of OLFM1 mRNAincreases expression 17175027
D008748 Methylcholanthrene Methylcholanthrene results in increased expression of OLFM1 mRNAincreases expression 20713471
D015058 1-Naphthylisothiocyanate 1-Naphthylisothiocyanate results in increased expression of OLFM1 mRNAincreases expression 12832660
C016340 o,p'-DDT o,p'-DDT results in increased expression of OLFM1 mRNAincreases expression 19371625
D010795 Phthalic Acids Phthalic Acids results in decreased expression of OLFM1 mRNAdecreases expression 15728792
D011078 Polychlorinated Biphenyls Polychlorinated Biphenyls analog results in increased expression of OLFM1 mRNAincreases expression 16474171
C025299 polyphenols polyphenols results in increased expression of OLFM1 mRNAincreases expression 16293270
D011374 Progesterone Progesterone results in decreased expression of OLFM1 mRNAdecreases expression 18037150
D011374 Progesterone Progesterone results in increased expression of OLFM1increases expression 17510236
C059514 resveratrol resveratrol results in decreased expression of OLFM1 mRNAdecreases expression 19371625
D013629 Tamoxifen Tamoxifen affects the expression of OLFM1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of OLFM1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of OLFM1 mRNAincreases expression 19933214
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.3414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.6415322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.3518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D058186 Acute Kidney Injury resveratrol 3.6616538975
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 12.9620464547 20127859
MESH:D000230 Adenocarcinoma Estradiol 12.9611473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 12.9614692618
MESH:D000230 Adenocarcinoma Fluorouracil 12.9617638652
MESH:D000230 Adenocarcinoma Genistein 12.9611473722
MESH:D000236 Adenoma 2-Acetylaminofluorene 19.7710737359
MESH:D000236 Adenoma Benzo(a)pyrene 19.776695378
MESH:D000236 Adenoma Diethylnitrosamine 19.776695378 10737359
MESH:D000236 Adenoma Methylcholanthrene 19.776695378 10545420
MESH:D000236 Adenoma resveratrol 19.7715688382
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.806705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.3519052882 17162532 19061943 16434500 17620307 18056438
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.3516835633
MESH:D000544 Alzheimer Disease resveratrol 2.5216162502 16183991
MESH:D000686 Amyloidosis Diethylstilbestrol 4.2815469931
MESH:D000740 Anemia Fluorouracil 8.0716511603 15504547 17963324
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.0711748828
MESH:D000756 Anemia, Sideroblastic Manganese 10.4016910769
MESH:D000756 Anemia, Sideroblastic manganese chloride 10.4016910769
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9415885639
MESH:D001169 Arthritis, Experimental resveratrol 6.9417115116
MESH:D050197 Atherosclerosis Methylcholanthrene 6.5611922910
MESH:D050197 Atherosclerosis resveratrol 6.5616873680 17967414
MESH:D001289 Attention Deficit Disorder with Hyperactivity Phthalic Acids 4.2220106747
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 2.8612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6315746008
MESH:D001862 Bone Resorption bisphenol A 3.6711985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.1317868700
MESH:D001930 Brain Injuries Progesterone 4.0515665606 15845082 15380490
MESH:D002545 Brain Ischemia resveratrol 4.0717600658
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 9.4517474063 20146248
MESH:D001943 Breast Neoplasms bisphenol A 9.4517123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 9.4517474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 9.4517129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 9.4512948864 17261762 17289903 17018787 19861407 16675129 18497071 14630087
MESH:D001943 Breast Neoplasms Fluorouracil 9.4519217205 16557594 18357371 15136595 16110121 16595493 18608205
MESH:D001943 Breast Neoplasms Genistein 9.4516873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methylcholanthrene 9.4517474063
MESH:D001943 Breast Neoplasms Progesterone 9.4517614352 15562024 16175315
MESH:D001943 Breast Neoplasms resveratrol 9.4517534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tamoxifen 9.4517049068 18629630 19487384 19189210 16273361 18821012 20544844 16202921 19289846 19084267 19288272 19189212 19410462 19221464 15668708 20135344 20859285 17893378 18425577 11161223 19059307 20005174 19115204 19142967 19244106 18855134 17440819 18997820 20390343 18351453 21138602 17242785 16873071 18815881 19200415 19011961 19103187 20065188 17261762 19066611 21152245 18984771 15565566 19155303 16818667
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 9.4520435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2516111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.4616051944
MESH:D002277 Carcinoma Fluorouracil 13.0317121937
MESH:D002277 Carcinoma Methylcholanthrene 13.0310545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 13.0316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3019066611
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 19.2316705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 19.2317761372 3581430 10737359 3084413 6705139
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 19.2319052882 16288022 19701751 18506893 19539802 19822196 16569478 20101231 19919837 17761372 18210153 16681979 20727157 17138121 20514400 21159647 19107877 16540662 10672840 18691550 17055752 19171122 18665156 18056438 18971187 17173139 16935385 16698587 17162532 16830150 18788625 19519916 20214788 11831363 19383236 17428255 16878318 16779866 19418558 16807293 3084413 18785209 20512989 20935162 19208518 19335982 18393292 20007298 16328049 20432363 16502159 19394651 10737359 18494052 20524982 17978847 18978308 3581430 20084675
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 19.2316924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 19.2316924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 19.2317088986 18930000 17045692 16799960 16332177 17971768
MESH:D006528 Carcinoma, Hepatocellular Genistein 19.2316924424
MESH:D006528 Carcinoma, Hepatocellular resveratrol 19.2316227395 19321006
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 19.2316924424
MESH:D002278 Carcinoma in Situ bisphenol A 4.7817123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.3816675471
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9218695887
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.2220419170
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.2216757204 18986760 16280240 17066447
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.2216227395
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.4317572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2518670907 18850075 16120746
MESH:D002318 Cardiovascular Diseases Genistein 7.0416332659
MESH:D002318 Cardiovascular Diseases resveratrol 7.0415458977
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 14.886135515
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.882727394 17174075 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.8818566989
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 14.8816192471
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.7419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.7416835633
MESH:D002761 Cholangitis 1-Naphthylisothiocyanate 5.9912912871
MESH:D002779 Cholestasis 1-Naphthylisothiocyanate 7.797624871 15500046 16629650 18590720 12927374 19486331 18164287 15913567
MESH:D002779 Cholestasis Ethinyl Estradiol 7.7917110522 16919318 17681005 16105132 17333356 15861022 11677210
MESH:D002780 Cholestasis, Intrahepatic 1-Naphthylisothiocyanate 5.6410220858 19407337
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0212621046 8697196 16354765 15668235 15340226
MESH:D003092 Colitis resveratrol 3.9216474422
MESH:D003110 Colonic Neoplasms Fluorouracil 8.0218772588 17016597 17725105 17287894 15001691 17169374 16510598 17018589 16340194 17172411
MESH:D003110 Colonic Neoplasms Genistein 8.0217182828
MESH:D003110 Colonic Neoplasms polyphenols 8.0216293270
MESH:D003110 Colonic Neoplasms resveratrol 8.0216338953
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.5017594712 16331619 14970324 16282729 17401013 17695437 17255274 18802399 15289873 20501625 15148649 18383874 18949393 16524972 17454858 16391804 17016601 18448328 18288408 16303861 18509181 17094418
MESH:D015179 Colorectal Neoplasms Polychlorinated Biphenyls 3.5015531428
MESH:D015179 Colorectal Neoplasms resveratrol 3.5016550006
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.8817141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.6216507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2515322242 10048152 20055451
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.3512952375 16002989
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.8118551238
MESH:D007644 Darier Disease Fluorouracil 4.5816733453
MESH:D003704 Dementia Polychlorinated Biphenyls 4.5116140633
MESH:D003711 Demyelinating Diseases Tamoxifen 4.1519031437
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6016873680
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.7920387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 6.7916647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.7917107852
MESH:D003928 Diabetic Nephropathies Estradiol 14.0019279558
MESH:D003928 Diabetic Nephropathies resveratrol 14.0016286809
MESH:D003928 Diabetic Nephropathies Tamoxifen 14.0019279558
MESH:D003929 Diabetic Neuropathies Progesterone 4.2817187935
MESH:D056486 Drug-Induced Liver Injury 1-Naphthylisothiocyanate 11.3617522070 20133375 7624871 18289764
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.3621346803 18551238
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.3619107877
MESH:D056486 Drug-Induced Liver Injury polyphenols 11.3619370779
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.3620420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6111462148
MESH:D004487 Edema resveratrol 6.248985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.2411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6915322242 18230668 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 20.2712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 20.2717692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 20.2717872969
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 20.2719031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 11.1916402032
MESH:D004714 Endometrial Hyperplasia Genistein 11.1916402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 16.6815700306 16804899
MESH:D016889 Endometrial Neoplasms Estradiol 16.6811473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Genistein 16.6811473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 16.6820544844 16202921 17893378 19155303
MESH:D004715 Endometriosis Progesterone 8.3216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.3210568697 9294722
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.6417923197
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9016302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3016530937
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.3015173087 16481741 16337965 16785472 17638652
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8611564622
MESH:D005234 Fatty Liver Diethylnitrosamine 12.0020387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.0015345470
MESH:D005234 Fatty Liver Tamoxifen 12.0019224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.7916534752 16611131 16002989 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.7916709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2511858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.3214745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 3.9719069698
MESH:D005354 Fibrosarcoma Methylcholanthrene 4.7310962813 14633661
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 2.7420067830
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 4.7416452187
MESH:D005909 Glioblastoma Genistein 7.0916598420
MESH:D005909 Glioblastoma Manganese 7.0917043766
MESH:D005910 Glioma Fluorouracil 2.7916145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.2515162350 18337622 15102660
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.0820471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.0811294989 10048152
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.106705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.226705139
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006505 Hepatitis 1-Naphthylisothiocyanate 4.4918590720
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6915340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.8215709030
MESH:D006561 Herpes Simplex resveratrol 3.9716876885
MESH:D019584 Hot Flashes Estradiol 3.5417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8315340226 16959395 8697196 18606429 16354765
MESH:D006937 Hypercholesterolemia resveratrol 3.8217188708
MESH:D006949 Hyperlipidemias resveratrol 3.8316873680
MESH:D006965 Hyperplasia Diethylstilbestrol 4.2314722030 12960047
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8318850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1217488730
MESH:D007021 Hypospadias Diethylstilbestrol 10.5516002989
MESH:D007021 Hypospadias Ethinyl Estradiol 10.5516569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 10.7915869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.7917600658
MESH:D007246 Infertility Diethylstilbestrol 4.1515036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2712013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.3517937319
MESH:D007249 Inflammation Diethylnitrosamine 18.5618785209
MESH:D007249 Inflammation polyphenols 18.5616366677
MESH:D007249 Inflammation Progesterone 18.5615869954
MESH:D007249 Inflammation resveratrol 18.5616366677
MESH:D007249 Inflammation Tamoxifen 18.5619457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 18.5612200463 12878042
MESH:D007251 Influenza, Human resveratrol 4.3316624496
MESH:D007333 Insulin Resistance bisphenol A 6.9916393666
MESH:D007333 Insulin Resistance Estradiol 6.9916627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.1516580747
MESH:D007674 Kidney Diseases Estradiol 2.4715618244
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 21.5416705839
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 21.5415003126 16762066 14681315
MESH:D007680 Kidney Neoplasms Estradiol 21.5415610895
MESH:D007680 Kidney Neoplasms Fluorouracil 21.5416985049
MESH:D007680 Kidney Neoplasms Tamoxifen 21.5418625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.8617184923
MESH:D007938 Leukemia Genistein 2.9218980019 17468513
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 3.4416087638
MESH:D008064 Lipidoses Tamoxifen 3.0117567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7118407596 18665156 20032147 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.7314716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Genistein 4.7317823541
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.7318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.7312878042
MESH:D008107 Liver Diseases 1-Naphthylisothiocyanate 6.4517184895
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4517034775
MESH:D008107 Liver Diseases polyphenols 6.4516698588
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 28.617678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 28.6118001218 14678523 10737359 11376686 16273603 10672840
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 28.6121137059 20195826
MESH:D008113 Liver Neoplasms Diethylnitrosamine 28.6118648771 19642983 18754104 15885732 20118626 19256749 18977376 20501860 19690152 2862719 19294768 12112319 19551842 16942905 19426721 20583210 20434301 10737359 15175105 21047994 19850985 20137499 19090486 21278145 19254457 19255062 18644402 20492335 18978307 21167192 20101389 12771043 2422723 21071580 19073162 19833225 19427195 19812893 19638242 19499222 20452335 19996281 20405173 9163691
MESH:D008113 Liver Neoplasms Diethylstilbestrol 28.6115890375 16712894
MESH:D008113 Liver Neoplasms Fluorouracil 28.6117045692 15113037 16603448 18383874
MESH:D008113 Liver Neoplasms resveratrol 28.6119812893 19073162 20405173 19321006
MESH:D008113 Liver Neoplasms Tamoxifen 28.6116684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.6116984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 21.706135515 2876786 2876784
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 21.70534488 6150874 1399818
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 21.7019519916 21159647 18282651 18775883 9362446 19009564 18164116 2563599 18079962 19539802 19004024 17854601 16842330 17174075 18308698 16267830 18093689 3124819 19126423 18253720 17942915 18544905
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 21.70598648 1399818
MESH:D008114 Liver Neoplasms, Experimental Polychlorinated Biphenyls 21.701423854
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 21.7012151625
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 10.2911376686
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 10.2920464547 20064080 18520028 20869020 20135361 18816296 17053015 18569708 6695378
MESH:D008175 Lung Neoplasms Diethylnitrosamine 10.2920970405 21163286 6695378 20512841
MESH:D008175 Lung Neoplasms Fluorouracil 10.2915246190
MESH:D008175 Lung Neoplasms Methylcholanthrene 10.2915390079 1399818 20970405 20512841 7750092 21163286 16271038 11893704 9230183 6695378 16337739 17909032 10545420
MESH:D008175 Lung Neoplasms Tamoxifen 10.2918625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.2919555203 11884234
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.5815086387
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.9415166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.3315700306
MESH:D016393 Lymphoma, B-Cell resveratrol 4.1017088997
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.7014749477
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.3016002989
MESH:D015674 Mammary Neoplasms, Animal resveratrol 9.3015688416
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 9.3019428831
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 17.4111807958 11408345 17203775 16891317
MESH:D008325 Mammary Neoplasms, Experimental Genistein 17.4114578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 17.4117203775 11408345
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 17.4111606380 8985016
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 17.4119196723 11731420 16827153 19196722 14580682
MESH:D020149 Manganese Poisoning Estradiol 21.1619453300
MESH:D020149 Manganese Poisoning Manganese 21.1616568477 19453300 16551646
MESH:D020149 Manganese Poisoning Tamoxifen 21.1619453300
MESH:D008545 Melanoma resveratrol 3.3217992120
MESH:D008545 Melanoma Tamoxifen 3.3212393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.9715990972
MESH:D008659 Metabolic Diseases resveratrol 4.1917112576
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 8.0016381670
MESH:D009062 Mouth Neoplasms Fluorouracil 8.0018986760 16757204
MESH:D009069 Movement Disorders Manganese 4.8116551646
MESH:D009101 Multiple Myeloma resveratrol 3.3217164350 17049120 14749477 16267019 17935668 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.6617962980
MESH:D009203 Myocardial Infarction Genistein 5.7117141266
MESH:D009203 Myocardial Infarction resveratrol 5.7117015251 17188708 16456233 16525036 16317513 17125593
MESH:D017202 Myocardial Ischemia resveratrol 8.4617015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.4612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.9816810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.9817141266
MESH:D009205 Myocarditis resveratrol 4.5517322642
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.6518551238 7678174
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.453581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.4519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4519410462
MESH:D009369 Neoplasms Benzo(a)pyrene 7.7311141357
MESH:D009369 Neoplasms Diethylstilbestrol 7.7315313581
MESH:D009369 Neoplasms Fluorouracil 7.7318600527 16928823 18239605
MESH:D009374 Neoplasms, Experimental resveratrol 3.808985016
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.7919189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5217289903
MESH:D009410 Nerve Degeneration Manganese 4.1216551646
MESH:D009421 Nervous System Malformations bisphenol A 28.5916427766 11399458
MESH:D009421 Nervous System Malformations Diethylstilbestrol 28.5911399458
MESH:D009421 Nervous System Malformations Estradiol 28.5911399458 16427766
MESH:D009421 Nervous System Malformations Genistein 28.5916427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 28.5914600291
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.9620387270
MESH:D019636 Neurodegenerative Diseases resveratrol 7.9617652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.2017929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9020387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3016436463
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.2516049721
MESH:D010024 Osteoporosis Genistein 3.1319401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 9.5016169203
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 9.5017513867
MESH:D010049 Ovarian Diseases bisphenol A 4.7811985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.5319401270
MESH:D010051 Ovarian Neoplasms Genistein 7.5319005980
MESH:D010051 Ovarian Neoplasms Progesterone 7.5317393432 16525653
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 5.0716540662
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.0719003803 16929163 16500647 15113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010300 Parkinson Disease Manganese 5.6811181820
MESH:D010300 Parkinson Disease Polychlorinated Biphenyls 5.6816702228
MESH:D020734 Parkinsonian Disorders Manganese 4.2916140633
MESH:D010382 Peliosis Hepatis 1-Naphthylisothiocyanate 13.0820133375
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 13.0812520081
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.9614722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.4615687265 16977796
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.382563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 21.5310548101
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 21.5317184923
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 21.5316679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 21.5311896295 11222880 11118676 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.9220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.9220887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.8917292933
MESH:D011471 Prostatic Neoplasms bisphenol A 2.8916740699
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.8915846301 17136230 15046698
MESH:D011471 Prostatic Neoplasms Estradiol 2.8916740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.8919082440 18626508
MESH:D011471 Prostatic Neoplasms Genistein 2.8916925846 15256057 15378649
MESH:D011471 Prostatic Neoplasms Polychlorinated Biphenyls 2.8915721890
MESH:D011471 Prostatic Neoplasms resveratrol 2.8917636462 15767336 17718901 17675339 17804756 16731767
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.8915067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.1015861022 16919318
MESH:D011629 Puberty, Precocious bisphenol A 4.5710548101
MESH:D012004 Rectal Neoplasms Fluorouracil 3.8318722050 15538739 16160472 18286688
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.3716325855
MESH:D015427 Reperfusion Injury resveratrol 3.1716314181 17520802 15827377 17058453 16317513
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7818045962
MESH:D012640 Seizures 2,6-dinitrotoluene 2.4018551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 8.8719755658 10029692
MESH:D012878 Skin Neoplasms resveratrol 8.8715837718 8985016
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 8.8716192470
MESH:D013088 Spermatocele Diethylstilbestrol 18.9016709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 18.9016709447
MESH:D013088 Spermatocele Tamoxifen 18.9016709447
MESH:D013119 Spinal Cord Injuries Progesterone 10.1715862959 16503802
MESH:D013119 Spinal Cord Injuries Tamoxifen 10.1719457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.242093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 3.2418456281
MESH:D013274 Stomach Neoplasms Fluorouracil 3.2417498489 18396642 17172411 19084572 18567086 17522103 15786421 16951190 16424979 19015929
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3016321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.7716684133 16045194
MESH:D013705 Temporomandibular Joint Disorders polyphenols 5.0417997062
MESH:D013921 Thrombocytopenia 1-Naphthylisothiocyanate 4.5720133375
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.837505956
MESH:D013978 Tibial Fractures Estradiol 4.4719048282
MESH:D014062 Tongue Neoplasms Fluorouracil 9.3816280240
MESH:D014062 Tongue Neoplasms resveratrol 9.3816227395
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 14.9416049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 14.9415289314 1399818 15867355
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 14.9417053015
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 14.9416452187 17306315 16712894
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 14.9416712894 17572228 8653321
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.1110091137
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 14.9016175088
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 14.9016803524
MESH:D002583 Uterine Cervical Neoplasms resveratrol 14.9017473185
MESH:D014591 Uterine Diseases bisphenol A 13.1114652134
MESH:D014591 Uterine Diseases Diethylstilbestrol 13.1114652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 14.9016690809 15809267
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 14.9014692618
MESH:D014594 Uterine Neoplasms resveratrol 14.9017044934
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.2316002989 16513791
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left resveratrol 4.0917488730
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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