AutismKB 2.0

Annotation Detail for TAB1


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Basic Information Top
Gene Symbol:TAB1 ( 3'-Tab1,MAP3K7IP1,MGC57664 )
Gene Full Name: TGF-beta activated kinase 1/MAP3K7 binding protein 1
Band: 22q13.1
Quick LinksEntrez ID:10454; OMIM: 602615; Uniprot ID:TAB1_HUMAN; ENSEMBL ID: ENSG00000100324; HGNC ID: 18157
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04010MAPK signaling pathway
hsa05140Leishmaniasis
hsa05145Toxoplasmosis
hsa04620Toll-like receptor signaling pathway
hsa04621NOD-like receptor signaling pathway
Pathway IDPathway Name
Signaling in Immune system
Pathway IDPathway Name
200016Noncanonical Wnt signaling pathway
200014p38 MAPK signaling pathway
200075IL1-mediated signaling events
200052Presenilin action in Notch and Wnt signaling
200054Regulation of p38-alpha and p38-beta
Pathway IDPathway Name
P00052TGF-beta signaling pathway
P00054Toll receptor signaling pathway
Pathway IDPathway Name
500449TRAF6 Mediated Induction of the antiviral cytokine IFN-alpha/beta cascade
500490Interleukin-1 signaling
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1944Breast cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
No data
No data
Pathway ID Pathway Name
REACT:25035 Innate immune response mediated by toll like receptors
KEGG:05140 Leishmaniasis
KEGG:04010 MAPK signaling pathway
KEGG:04621 NOD-like receptor signaling pathway
KEGG:04380 Osteoclast differentiation
REACT:6900 Signaling in Immune system
KEGG:04620 Toll-like receptor signaling pathway
KEGG:05145 Toxoplasmosis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA30604
  • No data
    No data
    Releated drug ID Related drug Name
    PA449972imiquimod
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018