Annotation Detail for PIBF1
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of PIBF1 mRNA | decreases expression | 20106945
20064835
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of PIBF1 mRNA | increases expression | 20106945
|
| D004394 |
Dydrogesterone |
Dydrogesterone affects the expression of PIBF1 protein | affects expression | 15760377
|
| D004394 |
Dydrogesterone |
Dydrogesterone results in increased expression of PIBF1 protein | increases expression | 16045524
|
| D015735 |
Mifepristone |
Mifepristone results in decreased expression of PIBF1 mRNA | decreases expression | 17701593
|
| D015735 |
Mifepristone |
Mifepristone results in decreased expression of PIBF1 protein | decreases expression | 17701593
|
| D011374 |
Progesterone |
Progesterone results in increased expression of PIBF1 mRNA | increases expression | 17701593
|
| D011374 |
Progesterone |
Progesterone results in increased expression of PIBF1 protein | increases expression | 17701593
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000033 |
Abortion, Threatened |
marker/mechanism |
|
| 15760377 |
| MESH:D000033 |
Abortion, Threatened |
|
Dydrogesterone |
7.70 | 15760377 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.05 | 20464547 20127859 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.84 | 6695378 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.56 | 19183758 |
| MESH:D020201 |
Brain Hemorrhage, Traumatic |
|
Progesterone |
5.95 | 17868700 |
| MESH:D001930 |
Brain Injuries |
|
Progesterone |
4.74 | 15845082 15380490 15665606 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.14 | 17474063 20146248 |
| MESH:D001943 |
Breast Neoplasms |
|
Progesterone |
2.14 | 15562024 17614352 16175315 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.13 | 20419170 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
2.76 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.17 | 19486331 |
| MESH:D003929 |
Diabetic Neuropathies |
|
Progesterone |
4.98 | 17187935 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Progesterone |
4.22 | 17692515 |
| MESH:D004715 |
Endometriosis |
|
Mifepristone |
10.60 | 16134523 |
| MESH:D004715 |
Endometriosis |
|
Progesterone |
10.60 | 16134523 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.07 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.23 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.62 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
4.76 | 8708960 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.82 | 20471113 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
4.96 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.20 | 10903974 |
| MESH:D020244 |
Infarction, Middle Cerebral Artery |
|
Progesterone |
4.89 | 15869954 |
| MESH:D007249 |
Inflammation |
|
Progesterone |
2.75 | 15869954 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.05 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.52 | 8314463 10903974 18776723 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
3.04 | 12371664 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
2.14 | 20195826 21137059 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 18520028 18569708 17053015 18816296 20135361 20464547 20064080 20869020 6695378 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Progesterone |
3.07 | 17203775 11408345 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.40 | 16801185 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.46 | 16381670 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
2.31 | 11141357 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.05 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.61 | 18481113 19348381 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Mifepristone |
5.50 | 16525653 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Progesterone |
5.50 | 17393432 16525653 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.55 | 12371664 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.91 | 17292933 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.32 | 16882103 |
| MESH:D012468 |
Salivary Gland Neoplasms |
|
Progesterone |
2.95 | 18045962 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.51 | 19755658 10029692 |
| MESH:D013119 |
Spinal Cord Injuries |
|
Progesterone |
4.82 | 16503802 15862959 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.29 | 17053015 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
4.59 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.05 | 17120751 |
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