AutismKB 2.0

Annotation Detail for ZNF238


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ZNF238 ( C2H2-171,RP58,TAZ-1,ZBTB18 )
Gene Full Name: zinc finger protein 238
Band: 1q44-qter
Quick LinksEntrez ID:10472; OMIM: 608433; Uniprot ID:ZN238_HUMAN; ENSEMBL ID: ENSG00000179456; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016572 Cyclosporine Cyclosporine results in decreased expression of ZNF238 mRNAdecreases expression 20106945
D005472 Fluorouracil Fluorouracil results in increased expression of ZNF238 mRNAincreases expression 16510598
D007213 Indomethacin Indomethacin results in decreased expression of ZNF238 mRNAdecreases expression 16984733
C030110 oxaliplatin oxaliplatin results in increased expression of ZNF238 mRNAincreases expression 16510598
D014810 Vitamin E Vitamin E results in increased expression of ZNF238 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Fluorouracil 4.9317638652
MESH:D000230 Adenocarcinoma Indomethacin 4.9316537180
MESH:D000236 Adenoma Indomethacin 3.6311497255
MESH:D016301 Alveolar Bone Loss Indomethacin 5.9817225004
MESH:D000544 Alzheimer Disease Indomethacin 2.7617627676 15579461
MESH:D000740 Anemia Fluorouracil 4.0615504547 16511603 17963324
MESH:D001014 Aortic Aneurysm Indomethacin 5.2910231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 5.3610388637
MESH:D018771 Arthralgia Indomethacin 5.782160914
MESH:D001172 Arthritis, Rheumatoid Indomethacin 2.8811248219
MESH:D001477 Bartter Syndrome Indomethacin 5.4710684365
MESH:D001929 Brain Edema Indomethacin 5.6411481608
MESH:D002545 Brain Ischemia Indomethacin 4.9612524144
MESH:D001943 Breast Neoplasms Fluorouracil 2.4416595493 18357371 18608205 19217205 16557594 16110121 15136595
MESH:D001943 Breast Neoplasms Indomethacin 2.4417401462
MESH:D002056 Burns Indomethacin 5.1910459503
MESH:D002100 Cachexia Indomethacin 5.5515141370 11239499 16537180 15625704
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.4116050911
MESH:D002276 Carcinoid Tumor Fluorouracil 5.2816051944
MESH:D002277 Carcinoma Fluorouracil 3.8517121937
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 3.4617088986 16332177 16799960 17045692 17971768 18930000
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 3.4616391822
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 5.2711053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.8918791128 14736730 11352223
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 7.2218695887
MESH:D002292 Carcinoma, Renal Cell Indomethacin 7.2217341418
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 5.2116757204 17066447 16280240 18986760
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 5.2115482327 12636206
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7612371664
MESH:D002764 Cholecystitis Indomethacin 5.7811181007
MESH:D002779 Cholestasis Cyclosporine 3.1719486331
MESH:D003110 Colonic Neoplasms Fluorouracil 6.3615001691 17016597 17287894 17172411 17725105 16340194 17018589 17169374 18772588 16510598
MESH:D003110 Colonic Neoplasms Indomethacin 6.3615625704 15936596 11260862 15637740 15786552 15963497
MESH:D003110 Colonic Neoplasms oxaliplatin 6.3616510598 16024531 16004971
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.7917594712 18509181 18949393 16331619 16303861 16282729 17255274 17454858 14970324 16524972 17094418 20501625 17016601 17695437 18383874 18448328 15148649 16391804 17401013 18802399 15289873 18288408
MESH:D015179 Colorectal Neoplasms Indomethacin 3.7917054584 12606626 18059344 11197048
MESH:D015179 Colorectal Neoplasms oxaliplatin 3.7917695437 18509181 18448328 17594712 17401013 17255274
MESH:D018352 Coronavirus Infections Indomethacin 6.3317302372
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D007644 Darier Disease Fluorouracil 5.3316733453
MESH:D003967 Diarrhea Indomethacin 4.237237001 7907874
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.6916133044 18043480 17190690 18446180 12774134 16326151
MESH:D004381 Duodenal Ulcer Indomethacin 4.5717045617 17329845 11595431 11991626 17202747 11595415 10671773 17151854 17351913 16699067 11535926
MESH:C538011 Eales disease Vitamin E 5.329068938
MESH:D004487 Edema Indomethacin 3.8710653021 7990266 8273558 19703484 8985016 16100529 7907874
MESH:D004715 Endometriosis Indomethacin 4.4915652904
MESH:D019446 Endotoxemia Indomethacin 5.0418509659
MESH:D004751 Enteritis Indomethacin 5.3616328016 17763956 10567023
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.4717980183
MESH:D004802 Eosinophilia Indomethacin 4.5311298111
MESH:D004938 Esophageal Neoplasms Fluorouracil 5.0216785472 16337965 17638652 16481741 15173087
MESH:D004938 Esophageal Neoplasms Indomethacin 5.0211005569
MESH:D005234 Fatty Liver Cyclosporine 3.2319224547
MESH:D005334 Fever Indomethacin 4.4710431976 17627676 11852909
MESH:D005354 Fibrosarcoma Indomethacin 5.4310962813
MESH:D005355 Fibrosis Cyclosporine 10.5612639820 12168785
MESH:D005355 Fibrosis Indomethacin 10.5617994277
MESH:D005499 Folliculitis Indomethacin 5.7811298111
MESH:D005756 Gastritis Indomethacin 5.3615046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.768708960
MESH:D005909 Glioblastoma Indomethacin 3.7812870263
MESH:D005910 Glioma Fluorouracil 6.6316145905
MESH:D005910 Glioma Indomethacin 6.6316487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.5711849393
MESH:D006073 Gout Indomethacin 5.8911248219
MESH:D006258 Head and Neck Neoplasms Fluorouracil 8.7618337622 15102660 15162350
MESH:D006258 Head and Neck Neoplasms Indomethacin 8.7615482327
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1516080930
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.9615720958
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.9415633222
MESH:D019698 Hepatitis C, Chronic Indomethacin 5.1215135802
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.8016863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.5814716179
MESH:D006930 Hyperalgesia Indomethacin 9.4112727271
MESH:D006930 Hyperalgesia oxaliplatin 9.4117418472
MESH:D034321 Hyperamylasemia Indomethacin 6.3317883296
MESH:D006940 Hyperemia Indomethacin 5.5512524144
MESH:D006949 Hyperlipidemias Indomethacin 4.5617546600
MESH:D006973 Hypertension Cyclosporine 2.2010903974
MESH:D007077 Ileal Diseases Indomethacin 5.6410574470 18306037
MESH:D007079 Ileitis Indomethacin 5.8916133968 10647630 10651667
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.9816133044
MESH:D007249 Inflammation Indomethacin 3.133291741 12568917 7812673
MESH:D007251 Influenza, Human Vitamin E 4.8316624496
MESH:D007410 Intestinal Diseases Indomethacin 4.8111686837 15831440 15610444 11855677 10210152 11713966 18236018 17994277 17329856
MESH:D019586 Intracranial Hypertension Indomethacin 5.9815241188
MESH:D007579 Jejunal Diseases Indomethacin 5.6418306037 10574470 16133968
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.0515604871
MESH:D007674 Kidney Diseases Cyclosporine 11.248314463 10903974 18776723
MESH:D007674 Kidney Diseases Indomethacin 11.2417190690
MESH:D007674 Kidney Diseases Vitamin E 11.2412488133
MESH:D007680 Kidney Neoplasms Cyclosporine 8.4212371664
MESH:D007680 Kidney Neoplasms Fluorouracil 8.4216985049
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 4.2111703811 12228301 10320625
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 4.1815631656 10785260 16572323
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 2.6818360721
MESH:D007964 Leukocytosis Indomethacin 5.9816537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 6.3317980183
MESH:D008101 Liver Abscess, Amebic Indomethacin 6.3311479899
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 2.8418194892
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.8416169303
MESH:D008113 Liver Neoplasms Fluorouracil 2.5815113037 17045692 16603448 18383874
MESH:D008171 Lung Diseases Vitamin E 3.4016863852
MESH:D008175 Lung Neoplasms Fluorouracil 3.7515246190
MESH:D008175 Lung Neoplasms Indomethacin 3.7516537180 11497255 11053908
MESH:D008175 Lung Neoplasms Vitamin E 3.7511062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.3315086387
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.4016801185
MESH:D008881 Migraine Disorders Indomethacin 3.9211903285
MESH:D009062 Mouth Neoplasms Fluorouracil 9.7518986760 16757204
MESH:D009062 Mouth Neoplasms Indomethacin 9.7512636206
MESH:D009362 Neoplasm Metastasis Indomethacin 3.2811053908 11239499 16537180
MESH:D009369 Neoplasms Fluorouracil 2.7516928823 18600527 18239605
MESH:D009374 Neoplasms, Experimental Indomethacin 4.6210663608 15625704
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.0517954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.6118481113 19348381
MESH:D019636 Neurodegenerative Diseases Indomethacin 4.2512349958
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.6616436463
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.786374098
MESH:D010003 Osteoarthritis Indomethacin 3.867009135
MESH:D010146 Pain Indomethacin 3.7617440234 13679232 17627676 3291741
MESH:D010149 Pain, Postoperative Indomethacin 5.2912538197 18702446
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7615113037 16929163 16500647 19003803
MESH:D010195 Pancreatitis Indomethacin 4.3215028970 17883296
MESH:D010257 Paraneoplastic Syndromes Indomethacin 6.3316537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.4712349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 6.3311903285
MESH:D010437 Peptic Ulcer Indomethacin 5.6911148446
MESH:D010518 Periodontitis Indomethacin 5.5217225004
MESH:D011230 Precancerous Conditions Cyclosporine 3.5512371664
MESH:D047928 Premature Birth Indomethacin 5.6117000239
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.2819082440 18626508
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2815084515
MESH:D011507 Proteinuria Indomethacin 4.5611849393
MESH:D011565 Psoriasis Cyclosporine 2.3216882103
MESH:D012004 Rectal Neoplasms Fluorouracil 4.3416160472 18286688 18722050 15538739
MESH:D012871 Skin Diseases Vitamin E 2.5118709164
MESH:D013272 Stomach Diseases Indomethacin 4.9617160473 15472012 17638125 16113693 16280098 17207306 10192188 18545984 18209964 15038085 10215738 10486359 16184426
MESH:D013274 Stomach Neoplasms Fluorouracil 2.7819084572 17522103 15786421 19015929 17498489 18567086 16424979 17172411 18396642 16951190
MESH:D013274 Stomach Neoplasms Indomethacin 2.7815609394
MESH:D013276 Stomach Ulcer Indomethacin 3.9511523592 18543354 17977527 11595415 10878458 16755016 18431645 12467913 16150113 11145282 18209962 12498302 16631530 14567935 1323529 11729361 11906479 12500499 12077510 18087811 15138204 17135157 17627676 18299717 16169175 10750652 10423059 16252198 18726076 17657623 16934674 18181030 15104355 16397915 12787963 18237397 17918041 18193104 17654042 11595431 15255614 17895592
MESH:D020521 Stroke Vitamin E 3.8116517955
MESH:D013964 Thyroid Neoplasms Indomethacin 3.8518791128 11352223 14736730
MESH:D014062 Tongue Neoplasms Fluorouracil 4.3416280240
MESH:D014456 Ulcer Indomethacin 5.4317380554 10574470
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.2316803524
MESH:D014605 Uveitis Cyclosporine 4.591336536
MESH:D014839 Vomiting Indomethacin 5.3611897121
MESH:D014985 Xerophthalmia Cyclosporine 5.0517120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA37608
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved