Annotation Detail for SLC25A17
Basic Information
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| Gene Symbol: | SLC25A17 ( PMP34 ) |
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| Gene Full Name: | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
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| Band: | 22q13.2 |
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| Quick Links | Entrez ID:10478; OMIM: 606795; Uniprot ID:PM34_HUMAN; ENSEMBL ID: ENSG00000100372; HGNC ID: 10987 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa04146 | Peroxisome |
| Pathway ID | Pathway Name |
|---|
| Metabolism of lipids and lipoproteins |
| Pathway ID | Pathway Name |
|---|
| 500819 | Alpha-oxidation of phytanate |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of SLC25A17 mRNA | affects expression | 21346803
|
| C472791 |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid |
3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of SLC25A17 mRNA | increases expression | 16788091
|
| D004041 |
Dietary Fats |
Dietary Fats results in increased expression of SLC25A17 mRNA | increases expression | 18042831
|
| C041786 |
palm oil |
palm oil results in increased expression of SLC25A17 mRNA | increases expression | 18042831
|
| D010634 |
Phenobarbital |
Phenobarbital results in increased expression of SLC25A17 mRNA | increases expression | 19270015
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of SLC25A17 mRNA | increases expression | 18301758
|
| D012643 |
Selenium |
Selenium results in decreased expression of SLC25A17 mRNA | decreases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
3.83 | 6195326 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.42 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
11.48 | 17620307 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
11.48 | 16434500 |
| MESH:D001161 |
Arteriosclerosis |
|
Dietary Fats |
4.25 | 15238619 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.43 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Dietary Fats |
2.25 | 20435547 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
3.12 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
3.12 | 17173139 6705139 1701930 20935162 20007298 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
2.95 | 6135515 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.61 | 4080065 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.03 | 19176532 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.14 | 17936198 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.38 | 18551238 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.53 | 18249437 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
4.16 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
4.16 | 15131321 |
| MESH:D050171 |
Dyslipidemias |
|
Dietary Fats |
3.65 | 18367378 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.31 | 1851702 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.76 | 12083418 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.47 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.31 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.01 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.79 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.61 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.41 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Dietary Fats |
8.65 | 17967931 18296743 19551842 19004024 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
8.65 | 20131406 19236843 |
| MESH:D005355 |
Fibrosis |
|
Dietary Fats |
3.88 | 18296743 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
7.48 | 20558911 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
7.48 | 17162251 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
9.70 | 16109766 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
9.70 | 18467677 19176532 16221962 19772884 |
| MESH:D006937 |
Hypercholesterolemia |
|
Dietary Fats |
3.87 | 21332399 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.45 | 20558911 |
| MESH:D006949 |
Hyperlipidemias |
|
Dietary Fats |
3.92 | 21332399 |
| MESH:D007249 |
Inflammation |
|
Dietary Fats |
2.55 | 20412841 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.64 | 16624496 |
| MESH:D007333 |
Insulin Resistance |
|
Dietary Fats |
7.82 | 18457598 11836018 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
7.82 | 16306350 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.17 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.21 | 16705839 |
| MESH:D008103 |
Liver Cirrhosis |
|
Dietary Fats |
7.12 | 18296743 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
7.12 | 21047994 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
2.22 | 19363144 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
7.93 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
7.93 | 15975961 8742319 21047994 19073162 19482888 19812893 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
7.93 | 16377806 15890375 20007298 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
6.49 | 2876786 2876784 6135515 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
6.49 | 1399818 6150874 18308698 17172636 2563599 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.92 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.88 | 15107826 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.86 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.24 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.16 | 16411023 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
4.87 | 17484760 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.26 | 18551238 7678174 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.06 | 17405874 |
| MESH:D009765 |
Obesity |
|
Dietary Fats |
4.62 | 21332399 20518802 19632207 18457598 18674790 11836018 20132043 16723640 17217161 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
4.62 | 20558911 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.70 | 16049721 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
4.76 | 17016548 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.57 | 16965848 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.33 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.87 | 2563599 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
4.94 | 12752131 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.50 | 19058328 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.53 | 18551238 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
6.53 | 3137016 16876388 4039156 11442880 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.22 | 6407741 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.26 | 1399818 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.38 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
4.71 | 10091137 |
| MESH:D015430 |
Weight Gain |
|
Dietary Fats |
3.99 | 16723640 |
Related Diseases/Disorders