Annotation Detail for SEMA6C
Basic Information
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| Gene Symbol: | SEMA6C ( SEMAY,m-SemaY,m-SemaY2 ) |
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| Gene Full Name: | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C |
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| Band: | 1q21.3 |
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| Quick Links | Entrez ID:10500; OMIM: 609294; Uniprot ID:SEM6C_HUMAN; ENSEMBL ID: ENSG00000143434; HGNC ID: 10740 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa04360 | Axon guidance |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of SEMA6C mRNA | affects expression | 21346803
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of SEMA6C mRNA | affects expression | 16483693
|
| D003840 |
Deoxycholic Acid |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SEMA6C mRNA | affects cotreatment|increases expression | 16556975
|
| C030691 |
gluconic acid |
[gluconic acid co-treated with Deoxycholic Acid] results in increased expression of SEMA6C mRNA | affects cotreatment|increases expression | 16556975
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
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| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.19 | 18287403 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
1.79 | 16705839 |
| MESH:D003110 |
Colonic Neoplasms |
|
Deoxycholic Acid |
3.61 | 16213893 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
4.58 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
2.05 | 18551238 21346803 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
3.32 | 16705839 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Deoxycholic Acid |
4.43 | 6150874 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
4.49 | 18551238 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
3.82 | 16049721 12819281 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
2.79 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
2.41 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
4.95 | 10091137 |
Related Diseases/Disorders