Annotation Detail for IPO8
Basic Information Top
| Gene Symbol: | IPO8 ( FLJ21954,FLJ26580,RANBP8 ) |
|---|---|
| Gene Full Name: | importin 8 |
| Band: | 12p11.21 |
| Quick Links | Entrez ID:10526; OMIM: 605600; Uniprot ID:IPO8_HUMAN; ENSEMBL ID: ENSG00000133704; HGNC ID: 9853 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of IPO8 mRNA | affects expression | 17562736 |
| D002117 | Calcitriol | Calcitriol results in decreased expression of IPO8 mRNA | decreases expression | 16847355 |
| C008493 | methylselenic acid | methylselenic acid results in increased expression of IPO8 mRNA | increases expression | 12517777 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 2.56 | 11237771 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 2.72 | 11237771 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 11461765 16393943 16081117 2444490 16781746 19923254 18071297 17562736 16227642 11529661 15968718 14550746 14986274 15619225 16177239 16485898 16109766 12540782 19416960 12594235 11834606 11739529 14725611 12392966 11287661 11743745 19739265 19164858 17906064 19420014 12705907 19370779 12958197 10774834 10915739 18713872 12153990 10663392 19085960 11421492 17522070 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 4.52 | 15138306 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19014921 12587719 12969438 16611625 19460945 11587558 19784758 16610002 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 5.52 | 15572423 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 3.53 | 15754350 16289102 16644109 18247401 12479363 | |
| MESH:D011471 | Prostatic Neoplasms | methylselenic acid | 3.53 | 16205645 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |