AutismKB 2.0

Annotation Detail for GLRX3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GLRX3 ( FLJ11864,GLRX4,GRX3,GRX4,PICOT,TXNL2,TXNL3,bA500G10.4 )
Gene Full Name: glutaredoxin 3
Band: 10q26.3
Quick LinksEntrez ID:10539; OMIM: 612754; Uniprot ID:GLRX3_HUMAN; ENSEMBL ID: ENSG00000108010; HGNC ID: 15987
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GLRX3 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GLRX3 mRNAaffects expression 21346803
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of GLRX3 mRNAdecreases expression 16788091
D000082 Acetaminophen Acetaminophen affects the expression of GLRX3 mRNAaffects expression 17562736
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GLRX3 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of GLRX3 mRNAincreases expression 20458559
C006780 bisphenol A bisphenol A results in decreased expression of GLRX3 mRNAdecreases expression 20678512
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of GLRX3 mRNAincreases expression 15336504
D002118 Calcium GLRX3 protein affects the susceptibility to Calciumaffects response to substance 16809552
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GLRX3 mRNAaffects cotreatment|affects expression 17602206
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of GLRX3 mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of GLRX3 mRNAincreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GLRX3 mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GLRX3 mRNAincreases expression 19400957
17942748
16174780
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GLRX3 mRNAincreases expression 16174780
19400957
D005419 Flavonoids Flavonoids results in increased expression of GLRX3 mRNAincreases expression 18035473
D015073 2-Acetylaminofluorene 2-Acetylaminofluorene results in increased expression of GLRX3 mRNAincreases expression 17317680
C051890 irinotecan irinotecan analog affects the expression of GLRX3 mRNAaffects expression 18927307
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of GLRX3 mRNAincreases expression 17616710
D010656 Phenylephrine GLRX3 protein affects the susceptibility to Phenylephrineaffects response to substance 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased expression of NPPA protein]decreases reaction|increases expression 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK8 protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCA protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCE protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine GLRX3 protein inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of PRKCZ protein]decreases reaction|increases activity|increases phosphorylation 16809552
D010656 Phenylephrine Phenylephrine results in increased expression of GLRX3 mRNAincreases expression 16809552
D013629 Tamoxifen Tamoxifen results in increased expression of GLRX3 mRNAincreases expression 19400957
D013629 Tamoxifen Tamoxifen results in increased expression of GLRX3 mRNAincreases expression 19400957
D014212 Tretinoin Tretinoin results in decreased expression of GLRX3 mRNAdecreases expression 16788091
D014415 Tunicamycin Tunicamycin results in increased expression of GLRX3 mRNAincreases expression 17127020
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.4214745880
MESH:D000138 Acidosis Ammonium Chloride 3.4318287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8117505938
MESH:D000230 Adenocarcinoma arsenic trioxide 4.1819825857 11798837
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1814692618
MESH:D000236 Adenoma 2-Acetylaminofluorene 6.7810737359
MESH:D000236 Adenoma Diethylnitrosamine 6.786695378 10737359
MESH:D002759 Adenoma, Bile Duct 2-Acetylaminofluorene 5.886705139
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.7716434500 19052882 18056438 17620307 17162532 19061943
MESH:D000505 Alopecia Tretinoin 3.5115955085
MESH:D000799 Angioedema Acetaminophen 3.7110982225
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 4.0017460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.3311256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.9415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.9416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2316292516
MESH:D001249 Asthma Tretinoin 2.3116456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4318445737
MESH:D001471 Barrett Esophagus Tretinoin 4.2716935849
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.7716206674
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.7716197459 16206674
MESH:D001862 Bone Resorption bisphenol A 3.7411985600
MESH:D001919 Bradycardia Phenylephrine 4.4115306635
MESH:D001943 Breast Neoplasms bisphenol A 1.9517123778
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9517474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.9519066611 19142967 20390343 19084267 18821012 18351453 20005174 18855134 17242785 19011961 19289846 15668708 19288272 16202921 18425577 19155303 19059307 20135344 18997820 15565566 19244106 18629630 19103187 20544844 19410462 11161223 21138602 19189210 20859285 19221464 20065188 18815881 17440819 21152245 16818667 19115204 19487384 19200415 17049068 17893378 16873071 19189212 18984771 17261762 16273361
MESH:D001943 Breast Neoplasms Tretinoin 1.9516443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.4616813970
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2011589617
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.3819066611
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.0316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 16.5816705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 16.5816705839
MESH:D006528 Carcinoma, Hepatocellular 2-Acetylaminofluorene 16.583084413 10737359 17761372 3581430 6705139
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.583084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.5815553829 14691202 11135700 16217749 15073043
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 16.5819919837 18971187 16569478 20935162 3084413 11831363 18788625 16779866 18393292 19519916 18506893 17428255 10672840 21159647 19052882 20512989 17978847 19822196 19701751 3581430 17055752 18785209 20514400 19418558 16288022 10737359 19171122 18665156 19208518 19394651 19539802 16807293 18210153 16681979 17138121 18691550 16935385 20084675 17761372 18056438 20727157 20524982 17173139 19335982 16878318 20007298 20214788 20432363 19383236 16698587 18978308 17162532 18494052 16328049 16540662 16830150 16502159 19107877 20101231
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 16.5816924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 16.581917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.8617123778
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7519014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0012490120
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 2.2516051514 16096774
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.5017572228
MESH:D006332 Cardiomegaly therapeutic 16809552
MESH:D006332 Cardiomegaly Phenylephrine 3.4616170337 15728586 11179087 17124262 11754973 17287366
MESH:D002386 Cataract Acetaminophen 6.9710977129
MESH:D002386 Cataract Tretinoin 6.9717460283
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.636135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.6312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.6317174075 21159647 7505956 2727394
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.4616129372
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.5719052882
MESH:D002779 Cholestasis Cyclosporine 7.4519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.4515861022 11677210 17333356 16919318 17110522 17681005 16105132
MESH:D002822 Choriocarcinoma Tretinoin 5.0316461808
MESH:D002972 Cleft Palate Tretinoin 2.619407595
MESH:D003092 Colitis Tretinoin 3.5717035595
MESH:D003110 Colonic Neoplasms irinotecan 2.5717287894 17725105
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6520501625
MESH:D015179 Colorectal Neoplasms irinotecan 2.6517159606 15273666 16391804 17454858 18259882 16303861 18509181
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0612609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.6410525206
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.649664655 16925845 8800419 9224671 9125849 10589399 9142499 14991402 9211117 17551590
MESH:D003490 Cyanosis 2,4-dinitrotoluene 10.4618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 10.4618551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9715213294
MESH:D003711 Demyelinating Diseases Tamoxifen 4.2319031437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.1620387270
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.3619279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 11.6118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 11.6121346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.6117906064 11834606 10663392 14986274 10915739 11461765 12705907 18071297 11287661 16227642 11529661 19416960 15619225 16109766 12540782 14725611 17562736 16781746 18713872 17522070 16485898 11421492 19085960 19739265 19164858 12958197 11739529 16081117 19370779 15968718 12594235 16393943 16177239 19923254 12153990 10774834 14550746 12392966 19420014 2444490 11743745
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 11.6117654400
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 11.6119107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9719426721
MESH:D004489 Edema, Cardiac Tretinoin 4.3418230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.5212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 8.5219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 7.1519155303 16202921 17893378 20544844
MESH:D016889 Endometrial Neoplasms Tretinoin 7.1516569247
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.9916302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.6112903497
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 4.6115547733 15623463 16510608 16704527 15264214 15150132 15878914 16805852 15547721
MESH:D005124 Eye Abnormalities Tretinoin 3.489664655 16938888
MESH:D005234 Fatty Liver arsenic trioxide 23.3615073043
MESH:D005234 Fatty Liver Cyclosporine 23.3619224547
MESH:D005234 Fatty Liver Diethylnitrosamine 23.3621071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.3615345470
MESH:D005234 Fatty Liver Tamoxifen 23.3614986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.1616709447
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.4014745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.0519069698
MESH:D005355 Fibrosis Cyclosporine 8.2612639820 12168785
MESH:D005355 Fibrosis Tretinoin 8.2617994277
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1316904648
MESH:D005756 Gastritis Acetaminophen 3.5516983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.098708960
MESH:D005909 Glioblastoma Tretinoin 2.9217312396
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.0316084493
MESH:D006330 Heart Defects, Congenital Tretinoin 2.8314991402 9664655
MESH:D006390 Hemangioendothelioma 2-Acetylaminofluorene 5.196705139
MESH:D006394 Hemangiosarcoma 2-Acetylaminofluorene 4.296705139
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2915720958
MESH:D006930 Hyperalgesia Acetaminophen 7.2816870215
MESH:D006930 Hyperalgesia Tretinoin 7.2816870215
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.4416778211
MESH:D006973 Hypertension Cyclosporine 5.2110903974
MESH:D006973 Hypertension Phenylephrine 5.218949925 12717712
MESH:D006984 Hypertrophy Phenylephrine 4.4312791704 18502941
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6816945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3412013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.4017937319
MESH:D007249 Inflammation Diethylnitrosamine 7.9818785209
MESH:D007249 Inflammation Flavonoids 7.9817296493
MESH:D007249 Inflammation Tamoxifen 7.9819457130
MESH:D007333 Insulin Resistance bisphenol A 3.2016393666
MESH:D007410 Intestinal Diseases Tretinoin 3.6417994277
MESH:D007569 Jaw Abnormalities Tretinoin 3.7817551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3115604871
MESH:D007674 Kidney Diseases Acetaminophen 5.5512587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 5.5518776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 16.8516705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 16.8516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 16.8512371664
MESH:D007680 Kidney Neoplasms Tamoxifen 16.8518625569
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 4.9216316344
MESH:D007938 Leukemia arsenic trioxide 6.1315070760
MESH:D007938 Leukemia Tretinoin 6.1317143497
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6712560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1816972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.0719077051
MESH:D007951 Leukemia, Myeloid Tretinoin 9.0716932348 19285840 16482212
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 3.8016467208 20471514 19850784 17050201 16968895
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.8019850784 16294345 17596541
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.3512018890 16823087 15622746 11161223 17869043 17649720 16331271 17107899 17217047 16891316 15748426 17712046 12679006 19642359 15336539 19035177 16330433 9834237 16966277 19075265 19225113 15213294 11468182 12712474 16112521
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.3515748426 17294898 17217047 16823087 17301526 17107899 16140955 17361223 12679006 19075265 17368321 17339181 19642359 16891316 19035177 17712046 16935935 9834237 19225113 17649720 16331271 16788101 16766008 19029980 17506722
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2216882451
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.219224671
MESH:D008064 Lipidoses Tamoxifen 3.0617567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.7518665156 18407596 20032147 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.4518564211
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 2.4518397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 3.7919014921 12587719 12969438 16611625 19460945 16610002 19784758 11587558
MESH:D008107 Liver Diseases Diethylnitrosamine 3.7917034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.1217185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 17.357678174
MESH:D008113 Liver Neoplasms 2-Acetylaminofluorene 17.3510672840 11376686 16273603 14678523 18001218 10737359
MESH:D008113 Liver Neoplasms arsenic trioxide 17.3514682389
MESH:D008113 Liver Neoplasms Clofibric Acid 17.3517602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.3519255062 19090486 20583210 19073162 15885732 2422723 19996281 21047994 21167192 19642983 20101389 21071580 18648771 10737359 19254457 9163691 18754104 19551842 12771043 20118626 20137499 18978307 19690152 19850985 18977376 20405173 15175105 20434301 18644402 20501860 12112319 2862719 19426721 19256749 20452335 16942905 19833225 20492335 19812893 19427195 19294768 19638242 21278145 19499222
MESH:D008113 Liver Neoplasms Tamoxifen 17.3516684651
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 13.516135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental 2-Acetylaminofluorene 13.516150874 534488 1399818
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.5120377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 13.5118253720 18775883 3124819 18093689 17942915 19539802 2563599 18079962 17174075 19009564 9362446 18544905 17854601 16267830 19126423 16842330 19004024 18308698 19519916 18282651 18164116 21159647
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2515213294
MESH:D008175 Lung Neoplasms 2-Acetylaminofluorene 4.7711376686
MESH:D008175 Lung Neoplasms arsenic trioxide 4.7711798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.7720970405 20512841 21163286 6695378
MESH:D008175 Lung Neoplasms Tamoxifen 4.7718625569
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.6319428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.5411731420 16827153 14580682 19196723 19196722
MESH:D020149 Manganese Poisoning Tamoxifen 4.4219453300
MESH:D008527 Medulloblastoma Tretinoin 2.7317453147
MESH:D008545 Melanoma Tamoxifen 3.2119393235 12393984
MESH:D008545 Melanoma Tretinoin 3.2116752155
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.0515990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4419513568
MESH:D008591 Meningomyelocele Tretinoin 4.2916940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6616801185
MESH:D052016 Mucositis irinotecan 4.8817159606
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0119417148 14977855 19549372 15949261 11468182
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5418349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 7.1416882451 16105982
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.1417596541
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.9118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 9.9118551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8316624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.253581430 9029167
MESH:D009362 Neoplasm Metastasis irinotecan 9.2518259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 9.2519393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.4719410462
MESH:D009369 Neoplasms Tretinoin 2.3516594593 16946489
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 3.8719189210 19196722 19200415
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1718481113 19348381
MESH:D009421 Nervous System Malformations bisphenol A 9.3716427766 11399458
MESH:D009421 Nervous System Malformations Tretinoin 9.379125849
MESH:D009436 Neural Tube Defects arsenic trioxide 7.0210525206
MESH:D009436 Neural Tube Defects Tretinoin 7.029142499
MESH:D009447 Neuroblastoma irinotecan 3.418761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.8218514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.8220387270
MESH:D017599 Neuroectodermal Tumors irinotecan 4.608761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.9920387270
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 8.5012819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 8.5016049721
MESH:D010024 Osteoporosis Calcium 3.7017882678
MESH:D010049 Ovarian Diseases bisphenol A 4.8611985600
MESH:D010051 Ovarian Neoplasms arsenic trioxide 4.7419769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Tretinoin 4.7416936753
MESH:D010146 Pain Acetaminophen 6.2316870215
MESH:D010146 Pain Tretinoin 6.2316870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.3415580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.3416540662
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.3415976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.5611578682
MESH:D010235 Paraganglioma arsenic trioxide 4.0419927285
MESH:D011230 Precancerous Conditions Cyclosporine 8.5712371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.572563599
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 3.8210548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 4.0920887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.6219131511
MESH:D011471 Prostatic Neoplasms bisphenol A 2.6216740699
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6215067354
MESH:D011507 Proteinuria Tretinoin 3.4816636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1815861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011625 Pterygium Tretinoin 4.6616723453
MESH:D011629 Puberty, Precocious bisphenol A 4.6510548101
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9816116481 16283617
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8316646077
MESH:D012640 Seizures 2,4-dinitrotoluene 5.5718551238
MESH:D012640 Seizures 2,6-dinitrotoluene 5.5718551238
MESH:D012852 Sinusitis Phenylephrine 4.577327846
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.608532709
MESH:D012878 Skin Neoplasms Tretinoin 5.6016467112
MESH:D013088 Spermatocele Ethinyl Estradiol 11.1316709447
MESH:D013088 Spermatocele Tamoxifen 11.1316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.9119457130
MESH:D013274 Stomach Neoplasms arsenic trioxide 6.2717007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 6.2718456281
MESH:D013274 Stomach Neoplasms irinotecan 6.2715723263
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 6.2717575124 12958204
MESH:D013274 Stomach Neoplasms Tretinoin 6.2717261132
MESH:D019966 Substance-Related Disorders bisphenol A 3.8516045194 16684133
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0415669648
MESH:D013964 Thyroid Neoplasms arsenic trioxide 11.4019014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 11.407505956
MESH:D013964 Thyroid Neoplasms Tretinoin 11.4016026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.6716051514
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8315213294
MESH:D014376 Tuberculosis Tretinoin 3.1516040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 15.2716049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 15.2716049721
MESH:D001749 Urinary Bladder Neoplasms 2-Acetylaminofluorene 15.271399818 15289314 15867355
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 15.2712973940 20435036 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 15.2716712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.5510091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.5510091137
MESH:D014581 Urticaria Acetaminophen 2.8510982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.5616129372
MESH:D014591 Uterine Diseases bisphenol A 4.8814652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.1714692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.4816752155
MESH:D014605 Uveitis Cyclosporine 3.851336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4215869587 14671159
MESH:D014820 Vitiligo Tretinoin 3.9316761959
MESH:D009396 Wilms Tumor Tretinoin 3.8516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.3117120751
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved