AutismKB 2.0

Annotation Detail for CEBPG


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Basic Information Top
Gene Symbol:CEBPG ( GPE1BP,IG/EBP-1 )
Gene Full Name: CCAAT/enhancer binding protein (C/EBP), gamma
Band: 19q13.11
Quick LinksEntrez ID:1054; OMIM: 138972; Uniprot ID:CEBPG_HUMAN; ENSEMBL ID: ENSG00000153879; HGNC ID: 1837
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of CEBPG mRNAincreases expression 19643169
C041525 3,3',4,5'-tetrahydroxystilbene 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
C041525 3,3',4,5'-tetrahydroxystilbene 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
C103505 AM 251 AM 251 results in increased expression of CEBPG mRNAincreases expression 16500647
D000643 Ammonium Chloride Ammonium Chloride affects the expression of CEBPG mRNAaffects expression 16483693
C520888 arachidin-1 arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
C520888 arachidin-1 arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
D016589 Astemizole Astemizole results in decreased expression of CEBPG mRNAdecreases expression 20221588
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of CEBPG mRNAdecreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of CEBPG mRNAdecreases expression 20382639
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CEBPG mRNAincreases expression 19150397
C095105 bexarotene bexarotene results in decreased expression of CEBPG mRNAdecreases expression 17178900
C006780 bisphenol A bisphenol A results in decreased expression of CEBPG mRNAdecreases expression 20678512
D002101 Cacodylic Acid Cacodylic Acid results in decreased expression of CEBPG mRNAdecreases expression 17720352
D002392 Catechin Catechin results in increased expression of CEBPG mRNAincreases expression 15465739
D016572 Cyclosporine Cyclosporine results in increased expression of CEBPG mRNAincreases expression 20106945
D004958 Estradiol Estradiol results in increased expression of CEBPG mRNAincreases expression 20068009
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of CEBPG mRNAincreases expression 17557909
D005419 Flavonoids Flavonoids results in decreased expression of CEBPG mRNAdecreases expression 15465739
D005419 Flavonoids Flavonoids results in increased expression of CEBPG mRNAincreases expression 18035473
D008070 Lipopolysaccharides 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
D008070 Lipopolysaccharides 3,3',4,5'-tetrahydroxystilbene inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
D008070 Lipopolysaccharides arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
D008070 Lipopolysaccharides arachidin-1 inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CEBPG mRNAincreases expression 17316017
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of CEBPG proteinincreases expression 17316017
D008070 Lipopolysaccharides resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
D008070 Lipopolysaccharides resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
C005219 methyl cellosolve methyl cellosolve results in increased expression of CEBPG mRNAincreases expression 19643169
D010936 Plant Extracts Plant Extracts results in decreased expression of CEBPG mRNAdecreases expression 15465739
C025299 polyphenols polyphenols results in decreased expression of CEBPG mRNAdecreases expression 15465739
D011374 Progesterone Progesterone results in increased expression of CEBPG mRNAincreases expression 18037150
C031280 pyrazole pyrazole results in increased expression of CEBPG mRNAincreases expression 17945193
C059514 resveratrol resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG mRNA]decreases reaction|increases expression 17316017
C059514 resveratrol resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of CEBPG protein]decreases reaction|increases expression 17316017
D018038 Sodium Selenite Sodium Selenite results in increased expression of CEBPG mRNAincreases expression 18175754
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CEBPG mRNAdecreases expression 18336851
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of CEBPG mRNAdecreases expression 20106945
D014212 Tretinoin Tretinoin results in decreased expression of CEBPG mRNAdecreases expression 17218384
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 13.306499812 6499823 6499820 6499796 7151721
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 13.306474471 6499812 3652986
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 13.3015322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.3518287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.7317505938
MESH:D058186 Acute Kidney Injury resveratrol 3.6616538975
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.8411850527 18653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.6820127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 6.6811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.6814692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.406695378
MESH:D000236 Adenoma resveratrol 6.4015688382
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.1716835633
MESH:D000505 Alopecia Tretinoin 3.4515955085
MESH:D000544 Alzheimer Disease Plant Extracts 4.4316962711
MESH:D000544 Alzheimer Disease resveratrol 4.4316162502 16183991
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.7611748828
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.143699323
MESH:D000799 Angioedema Astemizole 5.452883202
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 3.8719183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.2611256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 16.5115885639
MESH:D001169 Arthritis, Experimental Plant Extracts 16.5114686799
MESH:D001169 Arthritis, Experimental resveratrol 16.5117115116
MESH:D001169 Arthritis, Experimental Tretinoin 16.5116412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.2216292516
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 11.906499807 10689203 6499823
MESH:D053627 Asthenozoospermia methyl cellosolve 11.903987992
MESH:D001249 Asthma Tretinoin 2.2816456186
MESH:D001259 Ataxia 2-ethoxyethanol 5.267151721
MESH:D050197 Atherosclerosis resveratrol 3.1516873680 17967414
MESH:D001284 Atrophy 2-ethoxyethanol 10.7415850284 6499799
MESH:D001284 Atrophy methyl cellosolve 10.743699323 6705890 2626667
MESH:D053713 Azoospermia 2-ethoxyethanol 5.376499807 6492198
MESH:D001471 Barrett Esophagus Tretinoin 4.2016935849
MESH:D001724 Birth Weight 2-ethoxyethanol 6.302884743 6499823
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.3112125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.3116206674 16197459
MESH:D001836 Body Weight Changes 2-ethoxyethanol 11.326499796 7151721
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 11.3215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6315746008
MESH:D001862 Bone Resorption bisphenol A 3.6711985600
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 5.1317868700
MESH:D001930 Brain Injuries Progesterone 4.0515665606 15380490 15845082
MESH:D002545 Brain Ischemia Plant Extracts 9.7716041641
MESH:D002545 Brain Ischemia resveratrol 9.7717600658
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 5.6217474063 20146248
MESH:D001943 Breast Neoplasms bexarotene 5.6216344269 16818667
MESH:D001943 Breast Neoplasms bisphenol A 5.6217123778
MESH:D001943 Breast Neoplasms Cacodylic Acid 5.6217474063
MESH:D001943 Breast Neoplasms Estradiol 5.6217289903 17018787 19861407 14630087 17261762 12948864 18497071 16675129
MESH:D001943 Breast Neoplasms Progesterone 5.6217614352 15562024 16175315
MESH:D001943 Breast Neoplasms resveratrol 5.6217534123 16393696 17651959
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.6220435547
MESH:D001943 Breast Neoplasms Tretinoin 5.6216873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.3816813970
MESH:D002057 Burns, Chemical Plant Extracts 5.129625245
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.2516111702
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.6316835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.9516168501
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.3616924424
MESH:D006528 Carcinoma, Hepatocellular Plant Extracts 6.3618834353
MESH:D006528 Carcinoma, Hepatocellular resveratrol 6.3619321006 16227395
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.361917145
MESH:D002278 Carcinoma in Situ bisphenol A 4.7817123778
MESH:D018827 Carcinoma, Lewis Lung resveratrol 4.3816675471
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.1616247446
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 7.1920419170
MESH:D002294 Carcinoma, Squamous Cell resveratrol 7.1916227395
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 7.1916051514 16096774
MESH:D006332 Cardiomegaly Plant Extracts 6.6017645561
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6018850075 18670907 16120746
MESH:D002318 Cardiovascular Diseases resveratrol 3.3315458977
MESH:D002386 Cataract Tretinoin 2.9717460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 10.3120889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.3112371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.3118566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.3816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 12.946499794
MESH:D002764 Cholecystitis methyl cellosolve 12.946499794
MESH:D002779 Cholestasis Cyclosporine 7.2719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.2716919318 17681005 15861022 17333356 16105132 17110522 11677210
MESH:D002822 Choriocarcinoma Tretinoin 4.9516461808
MESH:D019457 Chromosome Breakage Sodium Selenite 4.5415894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.4712621046 8697196 16354765 15340226 15668235
MESH:D002972 Cleft Palate Tretinoin 5.479407595
MESH:D003092 Colitis resveratrol 8.9416474422
MESH:D003092 Colitis Tretinoin 8.9417035595
MESH:D003110 Colonic Neoplasms polyphenols 3.9416293270
MESH:D003110 Colonic Neoplasms resveratrol 3.9416338953
MESH:D015179 Colorectal Neoplasms resveratrol 2.2216550006
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.846499821 12530607
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.8417141729 14669216
MESH:D003327 Coronary Disease resveratrol 3.6216507316
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3815322242 20055451 10048152
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.3816925845 9664655 9224671 10589399 9211117 17551590 9142499 14991402 9125849 8800419
MESH:D003643 Death 2-ethoxyethanol 5.756499796
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.6016285004
MESH:D003921 Diabetes Mellitus, Experimental resveratrol 3.6016873680
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6217107852
MESH:D003928 Diabetic Nephropathies Estradiol 14.1319279558
MESH:D003928 Diabetic Nephropathies Plant Extracts 14.1319706694
MESH:D003928 Diabetic Nephropathies resveratrol 14.1316286809
MESH:D003929 Diabetic Neuropathies Progesterone 4.2817187935
MESH:D004244 Dizziness Astemizole 6.253105558
MESH:D056486 Drug-Induced Liver Injury polyphenols 8.5319370779
MESH:D056486 Drug-Induced Liver Injury pyrazole 8.5312499123
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 8.5315131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.5320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6111462148
MESH:D004487 Edema Plant Extracts 10.5212787963
MESH:D004487 Edema resveratrol 10.528985016
MESH:D004487 Edema Tetrachlorodibenzodioxin 10.5211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.2318230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.2318230668
MESH:D020964 Embryo Loss 2-ethoxyethanol 6.306499796
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 14.2212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 14.2217692515
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental resveratrol 14.2217872969
MESH:D016889 Endometrial Neoplasms Estradiol 6.9618566989 19148513 11473722
MESH:D016889 Endometrial Neoplasms Tretinoin 6.9616569247
MESH:D004715 Endometriosis Progesterone 8.3216134523
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 8.3210568697 9294722
MESH:D004719 Endomyocardial Fibrosis Plant Extracts 5.4715268973
MESH:D019446 Endotoxemia Lipopolysaccharides 4.1915328337 15821434 17637181
MESH:D020345 Enterocolitis, Necrotizing resveratrol 4.6417923197
MESH:D004802 Eosinophilia Astemizole 4.601355641
MESH:D004827 Epilepsy Plant Extracts 3.6219439326 19700373
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.1620426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.1616530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.3211564622
MESH:D005124 Eye Abnormalities Tretinoin 8.3216938888 9664655
MESH:D005234 Fatty Liver Cyclosporine 12.0819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.0815345470
MESH:D005234 Fatty Liver Plant Extracts 12.0815975614
MESH:D005313 Fetal Death 2-ethoxyethanol 10.156499820 7151721 2884743 7198755 6499823
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 10.1511858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 5.216499796
MESH:D005327 Fetal Resorption 2-ethoxyethanol 11.966499820 6499812
MESH:D005327 Fetal Resorption methyl cellosolve 11.966499821 3987992 6474471 6499812
MESH:D020567 Fetal Weight 2-ethoxyethanol 12.947151721 6499820 2884743
MESH:D020567 Fetal Weight methyl cellosolve 12.946499821 6474471 6499812
MESH:D005334 Fever Lipopolysaccharides 3.8311852909 9205823
MESH:D005355 Fibrosis Cyclosporine 13.5212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 13.5220067830
MESH:D005355 Fibrosis Tretinoin 13.5217994277
MESH:D005499 Folliculitis Astemizole 5.701671328
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.283652986
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.018708960
MESH:D005909 Glioblastoma Tretinoin 2.8717312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3810696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.0516096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.9516084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 10.4620471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 10.4610048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 10.469664655 14991402
MESH:D006333 Heart Failure Plant Extracts 3.7418097624
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.576499821
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 5.1910514026 20172899
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2115720958
MESH:D006461 Hemolysis 2-ethoxyethanol 11.6317874071 19051582
MESH:D006461 Hemolysis methyl cellosolve 11.6317874071
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 4.2016366002
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1511000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.6916120746 15340226 12621046
MESH:D006558 Herpes Genitalis Estradiol 4.8215709030
MESH:D006561 Herpes Simplex Plant Extracts 9.4210715843
MESH:D006561 Herpes Simplex resveratrol 9.4216876885
MESH:D015658 HIV Infections Plant Extracts 3.5712878215
MESH:D019584 Hot Flashes Estradiol 9.6317088409
MESH:D019584 Hot Flashes Plant Extracts 9.6317454163 16566672 14716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8316959395 8697196 18606429 16354765 15340226
MESH:D006930 Hyperalgesia Tretinoin 3.0516870215
MESH:D006937 Hypercholesterolemia resveratrol 3.8217188708
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.3616778211
MESH:D020138 Hyperhomocysteinemia Catechin 9.3417292331
MESH:D020138 Hyperhomocysteinemia Plant Extracts 9.3416484555
MESH:D006949 Hyperlipidemias Plant Extracts 8.9615268973 15975614
MESH:D006949 Hyperlipidemias resveratrol 8.9616873680
MESH:D006973 Hypertension Cyclosporine 4.6810903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.6818850075 18670907
MESH:D017379 Hypertrophy, Left Ventricular resveratrol 4.1217488730
MESH:D007021 Hypospadias Ethinyl Estradiol 3.6016569931 16945680
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 10.7915869954
MESH:D020244 Infarction, Middle Cerebral Artery resveratrol 10.7917600658
MESH:D007247 Infertility, Female 2-ethoxyethanol 9.756499823
MESH:D007247 Infertility, Female Ethinyl Estradiol 9.7512013081
MESH:D007248 Infertility, Male 2-ethoxyethanol 10.726499823
MESH:D007248 Infertility, Male Ethinyl Estradiol 10.7217937319
MESH:D007248 Infertility, Male methyl cellosolve 10.723987992
MESH:D007249 Inflammation Flavonoids 22.6017296493
MESH:D007249 Inflammation Lipopolysaccharides 22.6017237260 12878042 9205823 17255318 17963957
MESH:D007249 Inflammation Plant Extracts 22.6012787963 19332304 16366677 15997105
MESH:D007249 Inflammation polyphenols 22.6016366677
MESH:D007249 Inflammation Progesterone 22.6015869954
MESH:D007249 Inflammation resveratrol 22.6016366677
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 22.6012878042 12200463
MESH:D007251 Influenza, Human resveratrol 4.3316624496
MESH:D007333 Insulin Resistance bisphenol A 11.6216393666
MESH:D007333 Insulin Resistance Estradiol 11.6216393666 16627594
MESH:D007333 Insulin Resistance Sodium Selenite 11.6214714311
MESH:D007410 Intestinal Diseases Tretinoin 3.5617994277
MESH:D007414 Intestinal Neoplasms Plant Extracts 4.4312584176 12628509 12351151
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.4317255318
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.3016580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.3017551590 15992940
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2315604871
MESH:D007674 Kidney Diseases Cyclosporine 5.5418776723 10903974 8314463
MESH:D007674 Kidney Diseases Estradiol 5.5415618244
MESH:D007680 Kidney Neoplasms Cyclosporine 6.7112371664
MESH:D007680 Kidney Neoplasms Estradiol 6.7115610895
MESH:D007938 Leukemia Tretinoin 2.6717143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.5119285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0417596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute resveratrol 7.3216087638
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 7.3217712046 17368321 19075265 16140955 17107899 17506722 17339181 12679006 15748426 17217047 9834237 19225113 16331271 19029980 19035177 17301526 16766008 17361223 19642359 17649720 16788101 16891316 16935935 16823087 17294898
MESH:D007970 Leukopenia Lipopolysaccharides 4.4915821434
MESH:D017513 Lichen Nitidus Astemizole 6.252563723
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 8.076499821
MESH:D017880 Limb Deformities, Congenital Tretinoin 8.079224671
MESH:D008103 Liver Cirrhosis Plant Extracts 3.6217157831
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 6.4614716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 6.4612878042
MESH:D008106 Liver Cirrhosis, Experimental Plant Extracts 6.4615479170
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 6.4612878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 6.4616248980 18397230
MESH:D008107 Liver Diseases Plant Extracts 4.4817034775
MESH:D008107 Liver Diseases polyphenols 4.4816698588
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 10.0920195826 21137059
MESH:D008113 Liver Neoplasms Plant Extracts 10.0919168119
MESH:D008113 Liver Neoplasms resveratrol 10.0920405173 19812893 19073162 19321006
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 10.0916984957
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 1.9812151625
MESH:D008133 Long QT Syndrome Astemizole 4.4411989578 18472280
MESH:D055370 Lung Injury Lipopolysaccharides 3.8021114838
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 4.6918520028 17053015 20464547 20869020 18816296 20064080 20135361 18569708 6695378
MESH:D008175 Lung Neoplasms bexarotene 4.6917849452
MESH:D008175 Lung Neoplasms Plant Extracts 4.6920869020
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.6911884234 19555203
MESH:D016393 Lymphoma, B-Cell resveratrol 9.6217088997
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 9.6214737004
MESH:D008228 Lymphoma, Non-Hodgkin resveratrol 3.7014749477
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.9411161223
MESH:D008231 Lymphopenia methyl cellosolve 5.573699323
MESH:D008288 Malaria Astemizole 4.6016816845
MESH:D015674 Mammary Neoplasms, Animal resveratrol 4.0415688416
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 13.2315591091 19196722 19196723
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 13.2311408345 17203775 11807958 16891317
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 13.2311408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental resveratrol 13.2311606380 8985016
MESH:D020149 Manganese Poisoning Estradiol 4.2719453300
MESH:D008527 Medulloblastoma Tretinoin 2.7017453147
MESH:D008545 Melanoma resveratrol 3.3417992120
MESH:D008545 Melanoma Tretinoin 3.3416752155
MESH:D008591 Meningomyelocele Tretinoin 4.2216940565
MESH:D008659 Metabolic Diseases resveratrol 4.1917112576
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.5816801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.0316381670
MESH:D009101 Multiple Myeloma resveratrol 3.3217935668 17049120 14749477 17164350 16267019 16490592
MESH:D009134 Muscular Atrophy, Spinal resveratrol 4.6617962980
MESH:D009190 Myelodysplastic Syndromes Tretinoin 2.9617596541
MESH:D009203 Myocardial Infarction resveratrol 2.9417188708 16456233 16525036 17125593 16317513 17015251
MESH:D017202 Myocardial Ischemia resveratrol 8.4617015251 17125593
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.4612213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.1216810080
MESH:D009205 Myocarditis resveratrol 4.5517322642
MESH:D009336 Necrosis 2-ethoxyethanol 5.1320172899
MESH:D009369 Neoplasms Benzo(a)pyrene 4.6511141357
MESH:D009369 Neoplasms Tretinoin 4.6516946489 16594593
MESH:D009374 Neoplasms, Experimental resveratrol 3.808985016
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.5719196722
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1119348381 18481113
MESH:D009421 Nervous System Malformations bisphenol A 21.7711399458 16427766
MESH:D009421 Nervous System Malformations Estradiol 21.7711399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 21.7714600291
MESH:D009421 Nervous System Malformations Tretinoin 21.779125849
MESH:D009436 Neural Tube Defects Tretinoin 2.929142499
MESH:D019954 Neurobehavioral Manifestations Plant Extracts 4.9717168769
MESH:D019636 Neurodegenerative Diseases resveratrol 3.6417652729
MESH:D020078 Neurogenic Inflammation resveratrol 4.2017929310
MESH:D009759 Nystagmus, Pathologic Astemizole 6.256135121
MESH:D009765 Obesity Plant Extracts 3.0920132043 19056576
MESH:D009845 Oligospermia 2-ethoxyethanol 10.6720172899
MESH:D009845 Oligospermia methyl cellosolve 10.673987992
MESH:D015663 Osteoporosis, Postmenopausal resveratrol 4.0617513867
MESH:D010049 Ovarian Diseases bisphenol A 4.7811985600
MESH:D010051 Ovarian Neoplasms Estradiol 7.4919401270
MESH:D010051 Ovarian Neoplasms Progesterone 7.4916525653 17393432
MESH:D010051 Ovarian Neoplasms Tretinoin 7.4916936753
MESH:D010146 Pain AM 251 6.7318987195
MESH:D010146 Pain Tretinoin 6.7316870215
MESH:D010190 Pancreatic Neoplasms AM 251 5.5216500647
MESH:D010190 Pancreatic Neoplasms Tretinoin 5.5215976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4911578682
MESH:D010212 Papilloma Plant Extracts 4.2916517061 15173996
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.0412520081
MESH:D011014 Pneumonia Lipopolysaccharides 4.3412224865 11605937
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3618163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.0512371664
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 28.257198755 6499817 2884743
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 28.2510548101
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 28.257974496 12530607 6499817
MESH:D011297 Prenatal Exposure Delayed Effects resveratrol 28.2516679765
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 28.2511399792 11896295 11118676 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 9.9220887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 9.9220887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 1.8817292933
MESH:D011471 Prostatic Neoplasms bisphenol A 1.8816740699
MESH:D011471 Prostatic Neoplasms Estradiol 1.8816740699
MESH:D011471 Prostatic Neoplasms Plant Extracts 1.8814666653 17804756
MESH:D011471 Prostatic Neoplasms resveratrol 1.8817718901 17636462 16731767 17804756 15767336 17675339
MESH:D011471 Prostatic Neoplasms Sodium Selenite 1.8818760546
MESH:D011507 Proteinuria Tretinoin 3.4116636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.1015861022 16919318
MESH:D011565 Psoriasis Cyclosporine 2.1616882103
MESH:D011625 Pterygium Tretinoin 4.5816723453
MESH:D011629 Puberty, Precocious bisphenol A 4.5710548101
MESH:D051436 Renal Insufficiency, Chronic resveratrol 5.3716325855
MESH:D015427 Reperfusion Injury resveratrol 3.1716314181 17058453 15827377 17520802 16317513
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.5910835634
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6418990726
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.9016283617 16116481
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 5.2210822083
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.7818045962
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 16.8919755658 10029692
MESH:D012878 Skin Neoplasms Plant Extracts 16.8916517061 15173996
MESH:D012878 Skin Neoplasms resveratrol 16.898985016 15837718
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.8916192470
MESH:D012878 Skin Neoplasms Tretinoin 16.8916467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.7316709447
MESH:D013119 Spinal Cord Injuries Progesterone 4.0715862959 16503802
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.292093021 20155912
MESH:D013274 Stomach Neoplasms Tretinoin 2.2917261132
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 7.396499799
MESH:D013276 Stomach Ulcer Plant Extracts 7.3912787963 15255614 18193104 18237397 17135157
OMIM:601367 STROKE, ISCHEMIC resveratrol 4.3016321402
MESH:D019966 Substance-Related Disorders bisphenol A 3.7716045194 16684133
MESH:D013705 Temporomandibular Joint Disorders Plant Extracts 12.5617997062
MESH:D013705 Temporomandibular Joint Disorders polyphenols 12.5617997062
MESH:D013733 Testicular Diseases 2-ethoxyethanol 16.406499806 10514026 10048760
MESH:D013733 Testicular Diseases methyl cellosolve 16.406499806
MESH:D013733 Testicular Diseases pyrazole 16.406499806
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.9815821434
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.4211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6912697716
MESH:D013964 Thyroid Neoplasms Tretinoin 2.8716026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.4719048282
MESH:D014062 Tongue Neoplasms resveratrol 9.3016227395
MESH:D014062 Tongue Neoplasms Tretinoin 9.3016051514
MESH:D016171 Torsades de Pointes Astemizole 5.009583453 8256756
MESH:D014376 Tuberculosis Tretinoin 3.1016040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.2317053015
MESH:D001749 Urinary Bladder Neoplasms Cacodylic Acid 5.2315537745
MESH:D014581 Urticaria Astemizole 4.601976298 3080510 2565098 3134034 2859714 2885854 1683191 3097109 2147912 2568189 2568013 2883202
MESH:D002583 Uterine Cervical Neoplasms resveratrol 8.9217473185
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.9216129372
MESH:D014591 Uterine Diseases bisphenol A 4.8014652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.8314692618
MESH:D014594 Uterine Neoplasms resveratrol 8.8317044934
MESH:D014604 Uveal Neoplasms Tretinoin 4.4016752155
MESH:D014605 Uveitis Cyclosporine 3.771336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3514671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Plant Extracts 9.8418097624
MESH:D018487 Ventricular Dysfunction, Left resveratrol 9.8417488730
MESH:D020257 Ventricular Remodeling Plant Extracts 5.1018097624
MESH:D014717 Vertigo Astemizole 6.253105558
MESH:D014820 Vitiligo Tretinoin 3.8516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.0415886252
MESH:D009396 Wilms Tumor Tretinoin 3.7916287080
MESH:D014947 Wounds and Injuries Plant Extracts 4.0820213670 19894650
MESH:D014985 Xerophthalmia Cyclosporine 4.2317120751
Pathway ID Pathway Name
KEGG:05152 Tuberculosis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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