AutismKB 2.0

Annotation Detail for PRDX4


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Basic Information Top
Gene Symbol:PRDX4 ( AOE37-2,PRX-4 )
Gene Full Name: peroxiredoxin 4
Band: Xp22.11
Quick LinksEntrez ID:10549; OMIM: 606506; Uniprot ID:PRDX4_HUMAN; ENSEMBL ID: ENSG00000123131; HGNC ID: 17169
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C026702 16-hydroxyestrone 16-hydroxyestrone results in increased expression of PRDX4 mRNAincreases expression 18272409
C026702 16-hydroxyestrone 16-hydroxyestrone results in increased expression of PRDX4 proteinincreases expression 18272409
C022830 2-methoxyestradiol 2-methoxyestradiol results in increased expression of PRDX4 proteinincreases expression 18272409
D000643 Ammonium Chloride Ammonium Chloride affects the expression of PRDX4 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of PRDX4 proteinincreases expression 19364129
C099555 CD 437 CD 437 results in increased expression of PRDX4 mRNAincreases expression 12958071
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PRDX4 mRNAaffects cotreatment|affects expression 17602206
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNA]decreases reaction|increases expression 11007951
D016572 Cyclosporine Cyclosporine results in increased expression of PRDX4 mRNAincreases expression 20106945
D003840 Deoxycholic Acid PRDX4 protein results in decreased susceptibility to Deoxycholic Aciddecreases response to substance 12507930
D004041 Dietary Fats Dietary Fats results in increased expression of PRDX4 mRNAincreases expression 18042831
D004051 Diethylhexyl Phthalate Diethylhexyl Phthalate results in decreased expression of PRDX4 proteindecreases expression 16400681
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of PRDX4 mRNAincreases expression 17854601
D004052 Diethylnitrosamine RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PRDX4 mRNA]decreases reaction|increases expression 17854601
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PRDX4 mRNAaffects cotreatment|affects expression 17602206
D004958 Estradiol Estradiol results in increased expression of PRDX4 proteinincreases expression 18272409
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PRDX4 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRDX4 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of PRDX4 mRNAincreases expression 17108234
D005419 Flavonoids Flavonoids results in decreased expression of PRDX4 mRNAdecreases expression 18035473
C041786 palm oil palm oil results in increased expression of PRDX4 mRNAincreases expression 18042831
D010269 Paraquat Paraquat results in increased expression of PRDX4 mRNAincreases expression 12595580
D011794 Quercetin Quercetin results in increased expression of PRDX4 proteinincreases expression 15221776
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNA]decreases reaction|increases expression 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNAincreases expression 11007951
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PRDX4 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PRDX4 mRNAincreases expression 19465110
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of PRDX4 mRNAdecreases expression 18796159
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of PRDX4 proteinincreases expression 12361703
D014810 Vitamin E Vitamin E results in decreased expression of PRDX4 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Diethylhexyl Phthalate 8.436734493
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 8.4314514962 15322242 11752688
MESH:D000138 Acidosis Ammonium Chloride 3.4718287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.8617505938
MESH:D000230 Adenocarcinoma arsenic trioxide 6.9119825857 11798837
MESH:D000230 Adenocarcinoma Estradiol 6.9111473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9114692618
MESH:D000236 Adenoma Diethylnitrosamine 2.806695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.7718056438 19052882 17620307 19061943 17162532 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.7716835633
MESH:D000382 Agricultural Workers' Diseases Paraquat 3.6811874814
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.8711748828
MESH:D000743 Anemia, Hemolytic Quercetin 4.1617084956
MESH:D001161 Arteriosclerosis Dietary Fats 9.6215238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.6211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6115885639
MESH:D001260 Ataxia Telangiectasia Quercetin 4.8915336622
MESH:D001327 Autoimmune Diseases Quercetin 4.3219761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.6916206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.6912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7115746008
MESH:D001943 Breast Neoplasms 16-hydroxyestrone 3.7318272409
MESH:D001943 Breast Neoplasms 2-methoxyestradiol 3.7318223236 15219808
MESH:D001943 Breast Neoplasms Dietary Fats 3.7320435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 3.7317474063
MESH:D001943 Breast Neoplasms Estradiol 3.7317018787 17261762 18497071 16675129 17289903 14630087 19861407 12948864
MESH:D001943 Breast Neoplasms Quercetin 3.7318628248
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 3.7320435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.2411589617
MESH:D002105 Cadmium Poisoning Quercetin 5.4616962696
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3816111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 3.8416050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7316835633
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.4916217749 11135700 15073043 14691202 15553829
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 6.4918971187 19383236 16328049 19394651 20514400 19107877 19539802 16807293 10737359 19822196 18788625 17162532 19701751 20524982 18665156 18393292 17173139 18210153 19171122 3581430 16935385 20007298 3084413 20101231 10672840 17761372 18506893 18056438 17138121 20084675 20214788 19335982 16502159 16681979 19919837 16830150 16878318 17428255 20727157 18978308 19208518 19519916 16288022 18494052 17055752 20432363 19418558 20935162 17978847 11831363 16569478 16698587 20512989 16779866 18691550 21159647 18785209 16540662 19052882
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.4916924424
MESH:D006528 Carcinoma, Hepatocellular Quercetin 6.4912508355 19519916
MESH:D021441 Carcinoma, Pancreatic Ductal Quercetin 4.8717234771
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.0412490120
MESH:D006332 Cardiomegaly Quercetin 6.6419794523
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 6.6418670907 18850075 16120746
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.8012371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.802727394 7505956 17174075 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.8018566989
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.0719052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.0716835633
MESH:D002779 Cholestasis Cyclosporine 7.5619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.5617110522 11677210 16919318 17681005 17333356 16105132 15861022
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0715340226 12621046 8697196 16354765 15668235
MESH:D003110 Colonic Neoplasms Deoxycholic Acid 4.3316213893
MESH:D003110 Colonic Neoplasms Quercetin 4.3319440933 11134977 19056647 16640504 17191121 15741050 17148506
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.5920501625
MESH:D015179 Colorectal Neoplasms Quercetin 2.5918095365 18852136
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9814669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.1012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7210048152 15322242 20055451
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.7219769572
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.0115213294
MESH:D003876 Dermatitis, Atopic Diethylhexyl Phthalate 4.0116882537
MESH:D003921 Diabetes Mellitus, Experimental Quercetin 3.6619496084
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1520387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1517107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3319279558
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.6519107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.6520420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.6911462148
MESH:D050171 Dyslipidemias Dietary Fats 3.3918367378
MESH:C538011 Eales disease Vitamin E 4.629068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3012711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8218230668 16714409 15322242
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1012538720
MESH:D016889 Endometrial Neoplasms Estradiol 2.9211473722 18566989 19148513
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.949294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0416302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.2912903497
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9511564622
MESH:D005234 Fatty Liver arsenic trioxide 23.7715073043
MESH:D005234 Fatty Liver Cyclosporine 23.7719224547
MESH:D005234 Fatty Liver Dietary Fats 23.7717967931 19551842 19004024 18296743
MESH:D005234 Fatty Liver Diethylnitrosamine 23.7720387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 23.7715345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3711858732
MESH:D005355 Fibrosis Cyclosporine 20.4512168785 12639820
MESH:D005355 Fibrosis Dietary Fats 20.4518296743
MESH:D005355 Fibrosis Quercetin 20.4519474275
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.4520067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1816904648
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.138708960
MESH:D005909 Glioblastoma Quercetin 3.3319804834
MESH:D005910 Glioma Quercetin 3.0217643826
MESH:D005911 Gliosis Paraquat 5.0811124998
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5110696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.4210048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.4216080930
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3415720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2511000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8112621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.6716490937 16863852
MESH:D006558 Herpes Genitalis Estradiol 4.9515709030
MESH:D019584 Hot Flashes Estradiol 9.7817088409
MESH:D019584 Hot Flashes Vitamin E 9.7814716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.9616354765 16959395 18606429 15340226 8697196
MESH:D006937 Hypercholesterolemia Dietary Fats 3.5121332399
MESH:D006943 Hyperglycemia Quercetin 3.9518262572 11834736
MESH:D006949 Hyperlipidemias Dietary Fats 3.5321332399
MESH:D006973 Hypertension Cyclosporine 8.3910903974
MESH:D006973 Hypertension Quercetin 8.3918356687
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.3918850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.3812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5417937319
MESH:D007248 Infertility, Male Paraquat 6.544850670
MESH:D007249 Inflammation Dietary Fats 11.5820412841
MESH:D007249 Inflammation Diethylnitrosamine 11.5818785209
MESH:D007249 Inflammation Flavonoids 11.5817296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 11.5812878042 12200463
MESH:D007251 Influenza, Human Quercetin 10.8016624496
MESH:D007251 Influenza, Human Vitamin E 10.8016624496
MESH:D007333 Insulin Resistance Dietary Fats 7.1811836018 18457598
MESH:D007333 Insulin Resistance Estradiol 7.1816627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2516580747
MESH:D007627 Keloid Quercetin 4.8717086741
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.3615604871
MESH:D007674 Kidney Diseases Cyclosporine 14.048314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 14.0415618244
MESH:D007674 Kidney Diseases Quercetin 14.0416962696
MESH:D007674 Kidney Diseases Vitamin E 14.0412488133
MESH:D007680 Kidney Neoplasms Cyclosporine 7.0312371664
MESH:D007680 Kidney Neoplasms Estradiol 7.0315610895
MESH:D007938 Leukemia arsenic trioxide 6.3415070760
MESH:D007938 Leukemia Quercetin 6.3417468513
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.7117077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.2216972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3614633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.6819077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1216968895 16467208 17050201 20471514 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.169834237 17217047 15336539 12018890 16330433 16966277 17107899 15622746 11468182 12679006 16823087 17869043 17712046 19225113 19075265 15213294 16112521 16891316 12712474 11161223 19035177 19642359 15748426 16331271 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2716882451
MESH:D008103 Liver Cirrhosis Dietary Fats 6.4718296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.4718665156 18407596 19638242 18522880 20032147
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.8814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Quercetin 4.8812741479
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.8812878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 4.8816169303
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0817034775
MESH:D008113 Liver Neoplasms arsenic trioxide 17.5714682389
MESH:D008113 Liver Neoplasms Clofibric Acid 17.5717602206
MESH:D008113 Liver Neoplasms Diethylhexyl Phthalate 17.5711940454
MESH:D008113 Liver Neoplasms Diethylnitrosamine 17.5720137499 20583210 19690152 10737359 19499222 20452335 19638242 20501860 2422723 21167192 20101389 16942905 18648771 9163691 12771043 19996281 19642983 15885732 20118626 18754104 21278145 18644402 19551842 19073162 12112319 20405173 19294768 20434301 18977376 19812893 19254457 19850985 19090486 19833225 21071580 19256749 19426721 18978307 15175105 20492335 2862719 19427195 19255062 21047994
MESH:D008113 Liver Neoplasms Quercetin 17.5718980244
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.5716984957
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 18.0920377131
MESH:D008114 Liver Neoplasms, Experimental Deoxycholic Acid 18.096150874
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.0919009564 18282651 16267830 18775883 2563599 21159647 19539802 3124819 9362446 19126423 19519916 17942915 18308698 18253720 18079962 18164116 19004024 18093689 16842330 17854601 18544905 17174075
MESH:D008114 Liver Neoplasms, Experimental Quercetin 18.0919519916
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.0912151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2815213294
MESH:D008171 Lung Diseases Vitamin E 3.1216863852
MESH:D008175 Lung Neoplasms arsenic trioxide 6.4811798837 19825857
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.486695378 20970405 21163286 20512841
MESH:D008175 Lung Neoplasms Quercetin 6.4816280456
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.4811884234 19555203
MESH:D008175 Lung Neoplasms Vitamin E 6.4811062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5016891317 11408345 17203775 11807958
MESH:D020149 Manganese Poisoning Estradiol 4.4019453300
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7116801185
MESH:D009101 Multiple Myeloma arsenic trioxide 3.0419549372 19417148 15949261 11468182 14977855
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5918349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0916882451 16105982
MESH:D009203 Myocardial Infarction Quercetin 2.9519595682
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9512213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 8.3316810080
MESH:D015428 Myocardial Reperfusion Injury Quercetin 8.3319207477
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8716624393
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.533581430 9029167
MESH:D009369 Neoplasms Quercetin 2.7515185748
MESH:D009389 Neovascularization, Pathologic Estradiol 3.6517289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.3617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2118481113 19348381
MESH:D009410 Nerve Degeneration Paraquat 3.6516893418
MESH:D009421 Nervous System Malformations Estradiol 9.1811399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 9.1814600291
MESH:D009436 Neural Tube Defects arsenic trioxide 3.0610525206
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.2720387270
MESH:D020078 Neurogenic Inflammation Quercetin 4.2817929310
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0420387270
MESH:D009765 Obesity Dietary Fats 2.2720132043 18457598 19632207 16723640 18674790 17217161 20518802 11836018 21332399
MESH:D015663 Osteoporosis, Postmenopausal Quercetin 4.1319495926
MESH:D010051 Ovarian Neoplasms arsenic trioxide 11.1319769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms CD 437 11.1317474084
MESH:D010051 Ovarian Neoplasms Estradiol 11.1319401270
MESH:D010051 Ovarian Neoplasms Quercetin 11.1319005980
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.4815580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 8.4816540662
MESH:D010190 Pancreatic Neoplasms Quercetin 8.4816965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6011578682
MESH:D010235 Paraganglioma arsenic trioxide 4.0819927285
MESH:D010300 Parkinson Disease Paraquat 2.7816140633 16510128 15824117 11445065 15451049 11181820 12911755 11124998
MESH:D010302 Parkinson Disease, Secondary Paraquat 4.3416190885
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1712520081
MESH:D011014 Pneumonia Paraquat 4.3712504350
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4718163543
MESH:D011230 Precancerous Conditions Cyclosporine 14.8812371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 14.882563599
MESH:D011230 Precancerous Conditions Quercetin 14.8819056647
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1111399792 11118676 11222880 11896295
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8020887781
MESH:D011471 Prostatic Neoplasms 2-methoxyestradiol 1.9116356831
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.9119131511
MESH:D011471 Prostatic Neoplasms Estradiol 1.9116740699
MESH:D011471 Prostatic Neoplasms Quercetin 1.9117292933 14715546
MESH:D011471 Prostatic Neoplasms Vitamin E 1.9115084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.2316919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2016882103
MESH:D011658 Pulmonary Fibrosis Paraquat 2.8817997886 16324872
MESH:D012128 Respiratory Distress Syndrome, Adult Paraquat 3.8211700416
MESH:D012135 Respiratory Sounds Paraquat 3.9711874814
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.7518990726
MESH:D012162 Retinal Degeneration Paraquat 3.8016458197
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.8716646077
MESH:D012554 Schistosomiasis japonica Quercetin 5.4616862918
MESH:D012871 Skin Diseases Vitamin E 2.4218709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.0016192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.8616709447
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.4217007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.4218456281
MESH:D020521 Stroke Vitamin E 3.4516517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.0715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8212697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 6.9619014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 6.967505956
MESH:D013978 Tibial Fractures Estradiol 4.6019048282
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8815213294
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.3212845720 11780464 12973940 20435036
MESH:D001749 Urinary Bladder Neoplasms CD 437 8.3216720286
MESH:D001749 Urinary Bladder Neoplasms Quercetin 8.3216720314
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2114692618
MESH:D014605 Uveitis Cyclosporine 3.901336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5112125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.4614671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1715886252
MESH:D015430 Weight Gain Dietary Fats 3.6616723640
MESH:D014985 Xerophthalmia Cyclosporine 4.3617120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA33725
    • No data
    Releated disease ID Related disease Name
    PA443622Carcinoma, Non-Small-Cell Lung
    PA444818Lung Neoplasms
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA449383docetaxel
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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