AutismKB 2.0

Annotation Detail for HTATIP2


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Basic Information Top
Gene Symbol:HTATIP2 ( CC3,FLJ26963,SDR44U1,TIP30 )
Gene Full Name: HIV-1 Tat interactive protein 2, 30kDa
Band: 11p15.1
Quick LinksEntrez ID:10553; OMIM: 605628; Uniprot ID:HTAI2_HUMAN; ENSEMBL ID: ENSG00000109854; HGNC ID: 16637
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
1944Breast cancer
2022Liver cancer
2237Neoplasm metastasis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HTATIP2 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HTATIP2 mRNAaffects expression 21346803
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of HTATIP2 mRNAaffects expression 21346803
C029728 4-phenylenediamine 4-phenylenediamine results in increased expression of HTATIP2 mRNAincreases expression 16314067
D000082 Acetaminophen Acetaminophen affects the expression of HTATIP2 mRNAaffects expression 17562736
D000111 Acetylcysteine Acetylcysteine results in decreased expression of HTATIP2 mRNAdecreases expression 16084531
C006632 arsenic trioxide arsenic trioxide results in increased expression of HTATIP2 mRNAincreases expression 15761015
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in increased expression of HTATIP2 mRNAincreases expression 15336504
C459604 candoxin candoxin results in decreased expression of HTATIP2 mRNAdecreases expression 16309724
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HTATIP2 mRNAaffects cotreatment|affects expression 17602206
D003513 Cycloheximide Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNA]decreases expression|decreases reaction 11007951
D004041 Dietary Fats Dietary Fats results in decreased expression of HTATIP2 mRNAdecreases expression 18042831
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of HTATIP2 mRNAaffects cotreatment|affects expression 17602206
C045651 epigallocatechin gallate epigallocatechin gallate results in decreased expression of HTATIP2 mRNAdecreases expression 16084531
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HTATIP2 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HTATIP2 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HTATIP2 mRNAincreases expression 17557909
D005047 Etoposide HTATIP2 protein affects the susceptibility to Etoposideaffects response to substance 16217747
D005047 Etoposide HTATIP2 protein promotes the reaction [Etoposide results in increased activity of CASP9 protein]increases activity|increases reaction 16799960
D005047 Etoposide HTATIP2 protein promotes the reaction [Etoposide results in increased activity of PARP1 protein]increases activity|increases reaction 16799960
D005047 Etoposide HTATIP2 protein results in increased susceptibility to Etoposideincreases response to substance 16799960
D005472 Fluorouracil [Fluorouracil co-treated with irinotecan] results in increased expression of HTATIP2 mRNAaffects cotreatment|increases expression 16391804
D005472 Fluorouracil HTATIP2 protein results in increased susceptibility to Fluorouracilincreases response to substance 16799960
C051890 irinotecan [Fluorouracil co-treated with irinotecan] results in increased expression of HTATIP2 mRNAaffects cotreatment|increases expression 16391804
C030957 methylmercury II methylmercury II results in increased expression of HTATIP2 mRNAincreases expression 17905399
C029938 nickel sulfate nickel sulfate results in increased expression of HTATIP2 mRNAincreases expression 16314067
C041786 palm oil palm oil results in decreased expression of HTATIP2 mRNAdecreases expression 18042831
C006253 pirinixic acid pirinixic acid results in increased expression of HTATIP2 mRNAincreases expression 17950772
17426115
16221962
18301758
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of HTATIP2 mRNA]increases expression|increases reaction 17950772
C045950 propiconazole propiconazole results in increased expression of HTATIP2 mRNAincreases expression 19423681
C446685 systhane systhane results in increased expression of HTATIP2 mRNAincreases expression 19423681
C004648 testosterone enanthate testosterone enanthate affects the expression of HTATIP2 mRNAaffects expression 17440010
D013749 Tetrachlorodibenzodioxin Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNA]decreases expression|decreases reaction 11007951
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of HTATIP2 mRNAdecreases expression 11007951
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of HTATIP2 mRNAaffects binding|increases expression 16214954
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HTATIP2 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HTATIP2 mRNAincreases expression 17949056
18796159
D019772 Topotecan HTATIP2 protein affects the susceptibility to Topotecanaffects response to substance 16217747
C032910 triadimefon triadimefon results in increased expression of HTATIP2 mRNAincreases expression 19423681
D014303 Trinitrotoluene Trinitrotoluene affects the expression of HTATIP2 mRNAaffects expression 21346803
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 12.837525203
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 12.8311752688 15322242 14514962
MESH:D000014 Abnormalities, Drug-Induced Trinitrotoluene 12.837525203
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6817505938
MESH:D055371 Acute Lung Injury nickel sulfate 8.3411954676 16100012 19131640 12718980
MESH:D055371 Acute Lung Injury pirinixic acid 8.3418653653
MESH:D000230 Adenocarcinoma arsenic trioxide 6.6811798837 19825857
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.6814692618
MESH:D000230 Adenocarcinoma Fluorouracil 6.6817638652
MESH:D000236 Adenoma Diethylnitrosamine 2.7010737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 15.7516434500 19061943 17162532 19052882 18056438 17620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 15.7516434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 15.7516835633
MESH:D000740 Anemia Fluorouracil 7.9317963324 16511603 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 7.9311748828
MESH:D000799 Angioedema Acetaminophen 3.5810982225
MESH:D001161 Arteriosclerosis Dietary Fats 9.0515238619
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 9.0511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.5015885639
MESH:D001249 Asthma epigallocatechin gallate 3.3116516891
MESH:D001321 Autistic Disorder Acetaminophen 1.4418445737
MESH:D001327 Autoimmune Diseases epigallocatechin gallate 4.8119761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.9116206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.9119483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.9112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.5215340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6015746008
MESH:D019046 Bone Marrow Neoplasms Etoposide 4.8914601052
MESH:D001943 Breast Neoplasms Dietary Fats 2.2620435547
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2617474063
MESH:D001943 Breast Neoplasms Etoposide 2.2616322251
MESH:D001943 Breast Neoplasms Fluorouracil 2.2616595493 16110121 16557594 18357371 18608205 19217205 15136595
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.2620435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.0911589617
MESH:D002276 Carcinoid Tumor Fluorouracil 4.4016051944
MESH:D002277 Carcinoma Fluorouracil 7.5017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.5016835633
MESH:D006528 Carcinoma, Hepatocellular therapeutic 16799960
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 10.7916705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 10.7916705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 10.793084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 10.7915073043 14691202 15553829 16217749 11135700
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.7917761372 19519916 17138121 20935162 19171122 18785209 17978847 20084675 16328049 17428255 16569478 19394651 18393292 11831363 18210153 16807293 18506893 16698587 18788625 19418558 3084413 20101231 19919837 17162532 16288022 19107877 17173139 19383236 19539802 20524982 10672840 20432363 20214788 21159647 19052882 16681979 20514400 18691550 17055752 18056438 16935385 18978308 19701751 16779866 20727157 19822196 16502159 16830150 19208518 18971187 16878318 3581430 19335982 10737359 16540662 18494052 18665156 20007298 20512989
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 10.7917088986 17045692 17971768 16332177 18930000 16799960
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.6119014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.8918695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.8912490120
MESH:D002294 Carcinoma, Squamous Cell Acetylcysteine 4.8217015178
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 4.8216757204 16280240 17066447 18986760
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2218850075 18670907 16120746
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 11.5914694615
MESH:D002386 Cataract Acetaminophen 11.5910977129
MESH:D002386 Cataract Trinitrotoluene 11.5915817613 14694615
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 10.306135515
MESH:D002471 Cell Transformation, Neoplastic Acetylcysteine 10.3018226522
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 10.307505956 17174075 2727394 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 8.5919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 8.5916835633
MESH:D002779 Cholestasis Ethinyl Estradiol 7.1017333356 16919318 11677210 16105132 15861022 17681005 17110522
MESH:D002779 Cholestasis pirinixic acid 7.1019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7816354765 15340226 15668235 8697196 12621046
MESH:D002972 Cleft Palate triadimefon 5.7816781842
MESH:D003110 Colonic Neoplasms Fluorouracil 3.7917287894 17725105 17169374 16510598 18772588 15001691 16340194 17172411 17016597 17018589
MESH:D003110 Colonic Neoplasms irinotecan 3.7917725105 17287894
MESH:D015179 Colorectal Neoplasms arsenic trioxide 3.3620501625
MESH:D015179 Colorectal Neoplasms Fluorouracil 3.3615148649 17255274 16524972 17016601 20501625 18288408 17454858 18949393 16282729 17594712 18802399 17094418 18509181 15289873 16331619 18448328 18383874 16391804 17401013 14970324 17695437 16303861
MESH:D015179 Colorectal Neoplasms irinotecan 3.3618509181 16391804 17454858 18259882 16303861 17159606 15273666
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 14.3315095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 14.3314669216 17141729
MESH:D000013 Congenital Abnormalities Trinitrotoluene 14.3315095906
MESH:D023903 Coronary Restenosis arsenic trioxide 3.9312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 3.7310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.7310048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities triadimefon 3.7316875885 15834900
MESH:D003490 Cyanosis 2,4-dinitrotoluene 17.3118551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 17.3118551238
MESH:D003490 Cyanosis Trinitrotoluene 17.3118551238
MESH:D003550 Cystic Fibrosis Acetylcysteine 4.1519747007
MESH:D007644 Darier Disease Fluorouracil 4.5316733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.8515213294
MESH:D017449 Dermatitis, Allergic Contact 4-phenylenediamine 6.9818759875 16533241 19470301 11298694 16823706 11906362
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 6.9816823706 16780908 11298694
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.3018249437
MESH:D003877 Dermatitis, Contact 4-phenylenediamine 5.0911531941
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 6.8120387270
MESH:D003924 Diabetes Mellitus, Type 2 epigallocatechin gallate 6.8116988119
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 6.8117107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 20.8121346803 18551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 20.8118551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 20.8121346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 20.8119164858 11461765 10663392 18071297 11743745 19416960 12392966 17522070 10774834 11287661 15619225 14725611 12153990 17906064 18713872 16781746 12540782 11421492 17562736 19739265 12594235 19085960 11739529 12705907 19923254 12958197 16485898 10915739 16393943 14986274 11529661 16081117 19420014 16177239 19370779 11834606 14550746 16227642 2444490 16109766 15968718
MESH:D056486 Drug-Induced Liver Injury Acetylcysteine 20.8111287661
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 20.8119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 20.8120420201
MESH:D056486 Drug-Induced Liver Injury Trinitrotoluene 20.8118551238 21346803
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.8319426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.5711462148
MESH:D050171 Dyslipidemias Dietary Fats 3.2718367378
MESH:D004487 Edema pirinixic acid 5.7712083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.7711000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.6416714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.9412538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.809294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.8516302075
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3612903497
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.3616785472 16337965 16481741 15173087 17638652
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.8211564622
MESH:D005234 Fatty Liver arsenic trioxide 22.1415073043
MESH:D005234 Fatty Liver Dietary Fats 22.1419551842 17967931 18296743 19004024
MESH:D005234 Fatty Liver Diethylnitrosamine 22.1421071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 22.1415345470
MESH:D005234 Fatty Liver pirinixic acid 22.1420131406 19236843
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.2011858732
MESH:D005355 Fibrosis Dietary Fats 7.7718296743
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.7720067830
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.0116904648
MESH:D005756 Gastritis Acetaminophen 3.4116983495
MESH:D005910 Glioma Fluorouracil 2.7716145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.3310696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.2115102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1910048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.3820558911
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.1011000095
MESH:D006529 Hepatomegaly pirinixic acid 30.4216221962 19176532 18467677 19772884
MESH:D006529 Hepatomegaly propiconazole 30.4217178689 17178688
MESH:D006529 Hepatomegaly systhane 30.4217178689 17178688
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 30.4215340226 12621046 16120746
MESH:D006529 Hepatomegaly triadimefon 30.4217178688 17178689
MESH:D006529 Hepatomegaly Trinitrotoluene 30.4215817613
MESH:D006561 Herpes Simplex Etoposide 4.3010809021
MESH:D019247 HIV Wasting Syndrome testosterone enanthate 5.4817440010
MESH:D006689 Hodgkin Disease Etoposide 3.6616135485 18180244 16200630 17606976 15147373
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7816354765 15340226 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.5016870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.3621332399
MESH:D006943 Hyperglycemia pirinixic acid 2.9620558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.3721332399
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.8118850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 3.5516945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.2212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.3217937319
MESH:D007248 Infertility, Male Trinitrotoluene 6.3212150543
MESH:D007249 Inflammation Dietary Fats 7.4820412841
MESH:D007249 Inflammation Diethylnitrosamine 7.4818785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 7.4812878042 12200463
MESH:D007333 Insulin Resistance Dietary Fats 6.6818457598 11836018
MESH:D007333 Insulin Resistance pirinixic acid 6.6816306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.5416580747
MESH:D007569 Jaw Abnormalities triadimefon 9.5415834900 15992940
MESH:D007674 Kidney Diseases Acetaminophen 2.0515629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 11.2216705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 11.2216705839
MESH:D007680 Kidney Neoplasms Fluorouracil 11.2216985049
MESH:D007938 Leukemia arsenic trioxide 2.7015070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.5617077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.0416972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.2414633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.5319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0916467208 17050201 19850784 20471514 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.0516112521 17649720 19075265 16330433 15213294 19225113 11468182 16966277 17107899 17217047 16891316 16331271 19035177 17869043 9834237 11161223 16823087 12018890 12712474 15336539 17712046 12679006 19642359 15748426 15622746
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.1016882451
MESH:D008103 Liver Cirrhosis Dietary Fats 6.1518296743
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.1518522880 18407596 18665156 19638242 20032147
MESH:D008106 Liver Cirrhosis, Experimental epigallocatechin gallate 3.3517481882
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.3515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.3512878042
MESH:D008107 Liver Diseases Acetaminophen 8.8819784758 16611625 19460945 11587558 12969438 16610002 19014921 12587719
MESH:D008107 Liver Diseases Diethylnitrosamine 8.8817034775
MESH:D008107 Liver Diseases propiconazole 8.8819363144
MESH:D008107 Liver Diseases triadimefon 8.8819363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.0117185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 28.167678174
MESH:D008113 Liver Neoplasms arsenic trioxide 28.1614682389
MESH:D008113 Liver Neoplasms Clofibric Acid 28.1617602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 28.1619254457 15885732 19638242 19996281 20452335 21167192 19690152 20583210 21278145 20501860 12771043 20118626 18754104 18978307 18644402 21071580 19294768 19427195 12112319 19833225 15175105 19073162 18977376 2862719 20137499 2422723 18648771 19255062 19812893 19642983 20101389 19090486 19426721 19850985 19499222 21047994 20492335 16942905 20405173 20434301 9163691 19551842 10737359 19256749
MESH:D008113 Liver Neoplasms Fluorouracil 28.1616603448 17045692 15113037 18383874
MESH:D008113 Liver Neoplasms pirinixic acid 28.1620007298 16377806 15890375
MESH:D008113 Liver Neoplasms propiconazole 28.1619028983
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 28.1616984957
MESH:D008113 Liver Neoplasms triadimefon 28.1619028983
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 25.782876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 25.7820377131
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 25.7817942915 18775883 3124819 18544905 18093689 19009564 19126423 18079962 16842330 19539802 17174075 16267830 21159647 18164116 19519916 18253720 19004024 18308698 18282651 17854601 9362446 2563599
MESH:D008114 Liver Neoplasms, Experimental propiconazole 25.7817178689
MESH:D008114 Liver Neoplasms, Experimental systhane 25.7817178689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 25.7812151625
MESH:D008114 Liver Neoplasms, Experimental triadimefon 25.7817178689
MESH:D008133 Long QT Syndrome arsenic trioxide 3.1515213294
MESH:D008171 Lung Diseases Acetylcysteine 3.8812815614
MESH:D008175 Lung Neoplasms arsenic trioxide 4.5719825857 11798837
MESH:D008175 Lung Neoplasms Diethylnitrosamine 4.5720970405 20512841 6695378 21163286
MESH:D008175 Lung Neoplasms Fluorouracil 4.5715246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.5711884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.5315086387
MESH:D008223 Lymphoma Etoposide 3.7412556972 12854902
MESH:D008545 Melanoma epigallocatechin gallate 2.9517992120 11746506
MESH:D008546 Melanoma, Experimental Acetaminophen 3.3119513568
MESH:D009062 Mouth Neoplasms Fluorouracil 3.4316757204 18986760
MESH:D052016 Mucositis irinotecan 4.7417159606
MESH:D009101 Multiple Myeloma arsenic trioxide 2.9219417148 15949261 11468182 19549372 14977855
MESH:D009134 Muscular Atrophy, Spinal epigallocatechin gallate 5.2317962980
MESH:D009135 Muscular Diseases pirinixic acid 3.2516239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.4118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.9916105982 16882451
MESH:D009203 Myocardial Infarction pirinixic acid 2.0319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.8112213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7516411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 16.2618551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 16.267678174 18551238
MESH:D009336 Necrosis Trinitrotoluene 16.2618551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.7116624393
MESH:D009362 Neoplasm Metastasis Acetylcysteine 9.0714720322
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 9.079029167 3581430
MESH:D009362 Neoplasm Metastasis irinotecan 9.0718259882
MESH:D009369 Neoplasms Fluorouracil 4.5518600527 16928823 18239605
MESH:D009369 Neoplasms pirinixic acid 4.5517405874
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 2.9614600291
MESH:D009436 Neural Tube Defects Acetylcysteine 7.0919446573
MESH:D009436 Neural Tube Defects arsenic trioxide 7.0910525206
MESH:D009447 Neuroblastoma irinotecan 6.928761367
MESH:D009447 Neuroblastoma Topotecan 6.9215176712
MESH:D019636 Neurodegenerative Diseases Acetaminophen 7.4818514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 7.4820387270
MESH:D017599 Neuroectodermal Tumors irinotecan 4.478761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.8520387270
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.2616436463
MESH:D009765 Obesity Dietary Fats 4.2017217161 19632207 21332399 11836018 20132043 20518802 16723640 18457598 18674790
MESH:D009765 Obesity pirinixic acid 4.2020558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 19.7616049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 19.7616049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 19.7614694615
MESH:D009784 Occupational Diseases Trinitrotoluene 19.7612819281 17852074 14694615
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.3319769630 12452020 16624393
MESH:D010146 Pain Acetaminophen 2.1916870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 11.5815580305
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 11.5816540662
MESH:D010190 Pancreatic Neoplasms Etoposide 11.5819003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 11.5816500647 16929163 15113037 19003803
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.4411578682
MESH:D010235 Paraganglioma arsenic trioxide 3.9219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9812520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.3118163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.332563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 2.9311399792 11896295 11118676 11222880
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.7819131511
MESH:D011471 Prostatic Neoplasms Etoposide 2.7817172428
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.7818626508 19082440
MESH:D011537 Pruritus Ethinyl Estradiol 3.0515861022 16919318
MESH:D012004 Rectal Neoplasms Fluorouracil 3.7918286688 18722050 15538739 16160472
MESH:D015427 Reperfusion Injury pirinixic acid 2.2619058328
MESH:D012128 Respiratory Distress Syndrome, Adult Acetylcysteine 4.2812210543
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5918990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.6116646077
MESH:D012512 Sarcoma, Ewing's Etoposide 9.6114601052
MESH:D012640 Seizures 2,4-dinitrotoluene 8.8918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.8918551238
MESH:D012640 Seizures Trinitrotoluene 8.8918551238
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 5.188532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.1816192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6816709447
MESH:D013163 Splenomegaly Trinitrotoluene 4.9415817613
MESH:D013274 Stomach Neoplasms arsenic trioxide 4.5217007042
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 4.5218456281
MESH:D013274 Stomach Neoplasms Fluorouracil 4.5218567086 17522103 19015929 15786421 16951190 16424979 17498489 18396642 19084572 17172411
MESH:D013274 Stomach Neoplasms irinotecan 4.5215723263
MESH:D013276 Stomach Ulcer Acetylcysteine 3.7717918041
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.9315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.6412697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.9819014326
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 10.987505956
MESH:D013964 Thyroid Neoplasms triadimefon 10.9817178689
MESH:D014062 Tongue Neoplasms Fluorouracil 3.7616280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.7015213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 7.6916049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 7.6916049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 7.6912845720 20435036 11780464 12973940
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 11.1110091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 11.1110091137
MESH:D014581 Urticaria Acetaminophen 2.7410982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 3.6516803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.0514692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.3312125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.3014671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9815886252
MESH:D015430 Weight Gain Dietary Fats 3.5216723640
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB04535 - Octaethylene glycol
No data
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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