Annotation Detail for SLC35A1
Basic Information
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| Gene Symbol: | SLC35A1 ( CDG2F,CMPST,CST,FLJ76955,hCST ) |
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| Gene Full Name: | solute carrier family 35 (CMP-sialic acid transporter), member A1 |
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| Band: | 6q15 |
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| Quick Links | Entrez ID:10559; OMIM: 605634; Uniprot ID:S35A1_HUMAN; ENSEMBL ID: ENSG00000164414; HGNC ID: 11021 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| Transmembrane transport of small molecules |
| Pathway ID | Pathway Name |
|---|
| 500363 | Transport of nucleotide sugars |
| Desease ID | Desease Name |
|---|
| Inherited disorders of glycan/glycoprotein metabolism |
| H00119 | Congenital disorders of glycosylation (CDG) type II |
| Genetic disorders |
| Desease Name |
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| Congenital disorder of glycosylation, type IIf |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene results in increased expression of SLC35A1 mRNA | increases expression | 20406850
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of SLC35A1 mRNA | affects expression | 17555576
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
5.01 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.90 | 14692618 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
4.23 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.93 | 15885639 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
3.09 | 6135515 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.24 | 11677210 17681005 15861022 17110522 16919318 16105132 17333356 |
| OMIM:603585 |
CONGENITAL DISORDER OF GLYCOSYLATION, TYPE IIf |
marker/mechanism |
|
| |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.78 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.07 | 21346803 18551238 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.86 | 12538720 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.36 | 15345470 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.57 | 16945680 16569931 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
4.07 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.79 | 17937319 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.41 | 16705839 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.29 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.82 | 2876786 6135515 2876784 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.75 | 7678174 18551238 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.94 | 16049721 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.29 | 11578682 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
4.20 | 15861022 16919318 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.85 | 18551238 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
5.01 | 16709447 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.23 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.62 | 15669648 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.43 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.20 | 10091137 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.97 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
4.09 | 15869587 14671159 |
| Pathway ID |
Pathway Name |
|---|
| REACT:15518 |
Transmembrane transport of small molecules |
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