AutismKB 2.0

Annotation Detail for OLFM4


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Basic Information Top
Gene Symbol:OLFM4 ( GC1,GW112,KIAA4294,OLM4,OlfD,UNQ362,bA209J19.1,hGC-1,hOLfD )
Gene Full Name: olfactomedin 4
Band: 13q14.3
Quick LinksEntrez ID:10562; OMIM: NA; Uniprot ID:OLFM4_HUMAN; ENSEMBL ID: ENSG00000102837; HGNC ID: 17190
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1841Stomach cancer
2053Colon cancer
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016601 4-hydroxytamoxifen 4-hydroxytamoxifen results in increased expression of OLFM4 mRNAincreases expression 21048224
C006780 bisphenol A bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of OLFM4 mRNA]decreases reaction|increases expression 19228888
D003035 Cobalt [tungsten carbide binds to Cobalt] which results in decreased expression of OLFM4 mRNAaffects binding|decreases expression 20105288
D003907 Dexamethasone Dexamethasone results in increased expression of OLFM4 mRNAincreases expression 15679045
D003907 Dexamethasone Dexamethasone results in increased expression of OLFM4 proteinincreases expression 15679045
D004958 Estradiol EGF protein promotes the reaction [Estradiol results in increased expression of OLFM4 mRNA]increases expression|increases reaction 21048224
D004958 Estradiol Estradiol results in increased expression of OLFM4 mRNAincreases expression 21048224
D004958 Estradiol ICI 164384 inhibits the reaction [EGF protein promotes the reaction [Estradiol results in increased expression of OLFM4 mRNA]]decreases reaction|increases expression|increases reaction 21048224
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of OLFM4 mRNAincreases expression 17557909
C051781 ICI 164384 ICI 164384 inhibits the reaction [EGF protein promotes the reaction [Estradiol results in increased expression of OLFM4 mRNA]]decreases reaction|increases expression|increases reaction 21048224
D014284 Triiodothyronine bisphenol A inhibits the reaction [Triiodothyronine results in increased expression of OLFM4 mRNA]decreases reaction|increases expression 19228888
D014284 Triiodothyronine Triiodothyronine results in increased expression of OLFM4 mRNAincreases expression 19228888
C002802 tungsten carbide [tungsten carbide binds to Cobalt] which results in decreased expression of OLFM4 mRNAaffects binding|decreases expression 20105288
C002802 tungsten carbide tungsten carbide results in decreased expression of OLFM4 mRNAdecreases expression 20105288
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.2617505938
MESH:D000230 Adenocarcinoma Estradiol 4.3711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.3714692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7211256880
MESH:D001169 Arthritis, Experimental Dexamethasone 7.7717659584
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.7715885639
MESH:D001862 Bone Resorption bisphenol A 4.0711985600
MESH:D001943 Breast Neoplasms bisphenol A 2.1217123778
MESH:D001943 Breast Neoplasms Cobalt 2.1215986119
MESH:D001943 Breast Neoplasms Estradiol 2.1218497071 17289903 19861407 16675129 17261762 12948864 14630087 17018787
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.7516111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 1.7816924424
MESH:D002278 Carcinoma in Situ bisphenol A 5.2717123778
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.9118566989
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0217681005 17110522 16919318 15861022 16105132 11677210 17333356
MESH:D003110 Colonic Neoplasms Dexamethasone 2.5215824018
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.2917728286
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.6612438553
MESH:D003928 Diabetic Nephropathies Estradiol 3.5919279558
MESH:D003967 Diarrhea Dexamethasone 3.937237001
MESH:D004485 Eczema Dexamethasone 4.7012438553
MESH:D004487 Edema Dexamethasone 3.6019703484
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4212538720
MESH:D016889 Endometrial Neoplasms 4-hydroxytamoxifen 8.2119148513
MESH:D016889 Endometrial Neoplasms Estradiol 8.2119148513 18566989 11473722
MESH:D004715 Endometriosis marker/mechanism 21048224
MESH:D005234 Fatty Liver Ethinyl Estradiol 3.0215345470
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.137520565
MESH:D006558 Herpes Genitalis Estradiol 5.3515709030
MESH:D019584 Hot Flashes Estradiol 4.0717088409
MESH:D006973 Hypertension Cobalt 6.2117039479
MESH:D006973 Hypertension Dexamethasone 6.2117042910
MESH:D007021 Hypospadias Ethinyl Estradiol 4.0716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6217937319
MESH:D007249 Inflammation Dexamethasone 2.978960868 11099482
MESH:D007333 Insulin Resistance bisphenol A 7.8616393666
MESH:D007333 Insulin Resistance Estradiol 7.8616393666 16627594
MESH:D007674 Kidney Diseases Estradiol 2.6915618244
MESH:D007680 Kidney Neoplasms Estradiol 3.1515610895
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 2.6916718785
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.6914659978 14716833
MESH:D008173 Lung Diseases, Obstructive Cobalt 6.126434250
MESH:D008175 Lung Neoplasms Dexamethasone 2.2715824018 11195469
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.6816891317 11408345 11807958 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.8019453300
MESH:D009101 Multiple Myeloma Dexamethasone 3.6516118317 15867202 15744524
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.659809623
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.4416810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.0217289903
MESH:D009421 Nervous System Malformations bisphenol A 10.5516427766 11399458
MESH:D009421 Nervous System Malformations Estradiol 10.5511399458 16427766
MESH:D010049 Ovarian Diseases bisphenol A 5.2711985600
MESH:D010051 Ovarian Neoplasms Estradiol 2.2719401270
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9111578682
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.6521297632
MESH:D011297 Prenatal Exposure Delayed Effects bisphenol A 4.2410548101
MESH:D019048 Prostatic Intraepithelial Neoplasia bisphenol A 11.2520887781
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 11.2520887781
MESH:D011471 Prostatic Neoplasms bisphenol A 3.2216740699
MESH:D011471 Prostatic Neoplasms Estradiol 3.2216740699
MESH:D011537 Pruritus Ethinyl Estradiol 3.6015861022 16919318
MESH:D011629 Puberty, Precocious bisphenol A 5.0710548101
MESH:D011658 Pulmonary Fibrosis Cobalt 4.066434250
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 4.2411700416 18379247
MESH:D013088 Spermatocele Ethinyl Estradiol 4.2616709447
MESH:D013272 Stomach Diseases Dexamethasone 4.6015472012
MESH:D013276 Stomach Ulcer Dexamethasone 3.6915138204
MESH:D019966 Substance-Related Disorders bisphenol A 4.2716684133 16045194
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3315669648
MESH:D013978 Tibial Fractures Estradiol 5.0019048282
MESH:D014591 Uterine Diseases bisphenol A 5.3314652134
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5414692618
MESH:D014605 Uveitis Dexamethasone 5.131336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7514671159 15869587
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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