Annotation Detail for TBL3
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of TBL3 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of TBL3 mRNA | affects expression | 21346803
|
| D002995 |
Clofibric Acid |
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TBL3 mRNA | affects cotreatment|affects expression | 17602206
|
| D004052 |
Diethylnitrosamine |
[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of TBL3 mRNA | affects cotreatment|affects expression | 17602206
|
| D012643 |
Selenium |
Selenium results in increased expression of TBL3 mRNA | increases expression | 19244175
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000236 |
Adenoma |
|
Diethylnitrosamine |
3.03 | 6695378 10737359 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Diethylnitrosamine |
4.44 | 18056438 19052882 16434500 19061943 17162532 17620307 |
| MESH:D001943 |
Breast Neoplasms |
|
Diethylnitrosamine |
2.19 | 17474063 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.82 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.82 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Diethylnitrosamine |
4.82 | 11831363 19052882 19171122 17761372 19519916 20432363 18506893 16830150 3581430 20512989 16779866 20514400 21159647 19208518 16807293 10672840 19822196 10737359 16288022 19701751 18785209 16502159 19394651 19919837 17138121 16328049 20524982 18788625 20007298 16540662 20084675 18978308 20935162 18691550 17978847 17162532 16698587 19418558 17173139 18393292 19335982 16878318 17428255 19539802 18210153 20727157 18056438 18665156 19383236 16681979 18971187 16569478 3084413 19107877 18494052 17055752 20101231 16935385 20214788 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.48 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Diethylnitrosamine |
7.48 | 7505956 17174075 2727394 21159647 |
| MESH:D018281 |
Cholangiocarcinoma |
|
Diethylnitrosamine |
4.01 | 19052882 |
| MESH:D003092 |
Colitis |
|
Selenium |
4.26 | 17936198 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.56 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.56 | 18551238 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
Diethylnitrosamine |
2.25 | 20387270 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
9.72 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
9.72 | 18551238 21346803 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Diethylnitrosamine |
9.72 | 19107877 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Selenium |
9.72 | 15131321 |
| MESH:D004931 |
Esophageal Achalasia |
|
Diethylnitrosamine |
5.73 | 16302075 |
| MESH:D005234 |
Fatty Liver |
|
Diethylnitrosamine |
3.56 | 21071580 20387270 |
| MESH:D006333 |
Heart Failure |
|
Selenium |
3.27 | 17162251 |
| MESH:D007249 |
Inflammation |
|
Diethylnitrosamine |
2.53 | 18785209 |
| MESH:D007251 |
Influenza, Human |
|
Selenium |
4.81 | 16624496 |
| MESH:D007676 |
Kidney Failure, Chronic |
|
Selenium |
4.26 | 16518626 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.39 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.39 | 16705839 |
| MESH:D008103 |
Liver Cirrhosis |
|
Diethylnitrosamine |
2.99 | 18407596 19638242 18522880 20032147 18665156 |
| MESH:D008107 |
Liver Diseases |
|
Diethylnitrosamine |
2.16 | 17034775 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
8.17 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
Clofibric Acid |
8.17 | 17602206 |
| MESH:D008113 |
Liver Neoplasms |
|
Diethylnitrosamine |
8.17 | 19690152 20405173 19642983 21047994 20118626 20583210 15175105 12112319 21071580 9163691 20101389 19256749 18754104 21278145 20501860 19073162 19254457 20137499 19850985 19833225 19996281 19499222 19426721 10737359 21167192 16942905 20434301 19638242 20452335 19427195 19551842 20492335 19090486 12771043 18648771 19812893 15885732 18644402 19255062 2862719 18977376 18978307 2422723 19294768 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
6.61 | 6135515 2876786 2876784 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Diethylnitrosamine |
6.61 | 17854601 3124819 18308698 18282651 16267830 18544905 21159647 18093689 19004024 19126423 2563599 18164116 18079962 18775883 9362446 18253720 19539802 17942915 19519916 16842330 19009564 17174075 |
| MESH:D008175 |
Lung Neoplasms |
|
Diethylnitrosamine |
1.76 | 20970405 20512841 6695378 21163286 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
Selenium |
2.97 | 15318939 |
| MESH:D008654 |
Mesothelioma |
|
Selenium |
2.90 | 15107826 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
12.21 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
12.21 | 18551238 7678174 |
| MESH:D009362 |
Neoplasm Metastasis |
|
Diethylnitrosamine |
2.68 | 9029167 3581430 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Diethylnitrosamine |
3.65 | 20387270 |
| MESH:D009461 |
Neurologic Manifestations |
|
Diethylnitrosamine |
5.73 | 20387270 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
10.06 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
10.06 | 16049721 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Diethylnitrosamine |
2.52 | 16540662 |
| MESH:D010954 |
Plasmacytoma |
|
Selenium |
5.50 | 15087411 |
| MESH:D011230 |
Precancerous Conditions |
|
Diethylnitrosamine |
3.88 | 2563599 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.65 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.65 | 18551238 |
| MESH:D013274 |
Stomach Neoplasms |
|
Diethylnitrosamine |
1.76 | 18456281 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Diethylnitrosamine |
3.25 | 7505956 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.39 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.39 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.86 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.86 | 10091137 |
| Pathway ID |
Pathway Name |
|---|
| KEGG:03008 |
Ribosome biogenesis in eukaryotes |
Related Pathway Information