AutismKB 2.0

Annotation Detail for GAS2L1


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Basic Information Top
Gene Symbol:GAS2L1 ( GAR22,MGC17243 )
Gene Full Name: growth arrest-specific 2 like 1
Band: 22q12.2
Quick LinksEntrez ID:10634; OMIM: 602128; Uniprot ID:GA2L1_HUMAN; ENSEMBL ID: ENSG00000185340; HGNC ID: 16955
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of GAS2L1 mRNAaffects expression 17562736
D016572 Cyclosporine Cyclosporine results in decreased expression of GAS2L1 mRNAdecreases expression 20106945
C014347 decitabine [decitabine co-treated with vorinostat] affects the expression of GAS2L1 mRNAaffects cotreatment|affects expression 17330099
D004041 Dietary Fats Dietary Fats results in decreased expression of GAS2L1 mRNAdecreases expression 18042831
C041786 palm oil palm oil results in decreased expression of GAS2L1 mRNAdecreases expression 18042831
C111237 vorinostat [decitabine co-treated with vorinostat] affects the expression of GAS2L1 mRNAaffects cotreatment|affects expression 17330099
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001161 Arteriosclerosis Dietary Fats 4.3115238619
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms decitabine 2.1318320071 19208741
MESH:D001943 Breast Neoplasms Dietary Fats 2.1320435547
MESH:D001943 Breast Neoplasms vorinostat 2.1316144943
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.403084413
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6619215824
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 2.7312371664
MESH:D002779 Cholestasis Cyclosporine 3.1419486331
MESH:D003110 Colonic Neoplasms decitabine 2.3717616700
MESH:D015179 Colorectal Neoplasms decitabine 2.1018981723
MESH:D003967 Diarrhea vorinostat 4.8720479100
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6512153990 10915739 11743745 12958197 16081117 12705907 2444490 11287661 19164858 16177239 16393943 11421492 16109766 17522070 12594235 18071297 19370779 16781746 17562736 14725611 11739529 19085960 15619225 16227642 12392966 11834606 11529661 17906064 10774834 14986274 19420014 15968718 10663392 19739265 18713872 11461765 19923254 14550746 16485898 12540782 19416960
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.6419294695
MESH:D005221 Fatigue vorinostat 6.0620479100
MESH:D005234 Fatty Liver Cyclosporine 8.8419224547
MESH:D005234 Fatty Liver Dietary Fats 8.8417967931 18296743 19551842 19004024
MESH:D005355 Fibrosis Cyclosporine 10.1212639820 12168785
MESH:D005355 Fibrosis Dietary Fats 10.1218296743
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006258 Head and Neck Neoplasms decitabine 3.6919215824
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007248 Infertility, Male decitabine 3.4017581917
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3011836018 18457598
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Acetaminophen 6.3415629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 6.3418776723 10903974 8314463
MESH:D007680 Kidney Neoplasms Cyclosporine 3.0012371664
MESH:D007938 Leukemia decitabine 3.2118980019 19235587
MESH:D007951 Leukemia, Myeloid decitabine 4.3319117987 18454857 17236224
MESH:D015470 Leukemia, Myeloid, Acute marker/mechanism 17330099
MESH:D015470 Leukemia, Myeloid, Acute decitabine 2.4218704418 17679729 18206229 18460780 19387464 19010910
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 5.9818055864
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0318296743
MESH:D008107 Liver Diseases Acetaminophen 1.6912969438 16610002 19460945 16611625 19784758 12587719 19014921 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5416871587 17185352
MESH:D008223 Lymphoma decitabine 3.6419470736
MESH:D016410 Lymphoma, T-Cell, Cutaneous vorinostat 6.1020479100
MESH:D008545 Melanoma decitabine 2.2817785578 16505122
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009101 Multiple Myeloma decitabine 3.5618172295
MESH:D009190 Myelodysplastic Syndromes decitabine 3.5419010910 16882708 19157545 18608210
MESH:D009325 Nausea vorinostat 6.0420479100
MESH:D009369 Neoplasms decitabine 2.8417925555 19116145 19470736
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5718481113 19348381
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009765 Obesity Dietary Fats 2.3420518802 17217161 11836018 21332399 19632207 18457598 20132043 16723640 18674790
MESH:D010051 Ovarian Neoplasms decitabine 2.7219259094 19331143
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010190 Pancreatic Neoplasms decitabine 2.8519294695
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D055728 Primary Myelofibrosis decitabine 5.1517616702
MESH:D011471 Prostatic Neoplasms vorinostat 4.4217218635
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D012208 Rhabdomyosarcoma decitabine 4.7519155313
MESH:D013274 Stomach Neoplasms decitabine 2.1019037991
MESH:D013921 Thrombocytopenia vorinostat 5.2820479100
MESH:D013964 Thyroid Neoplasms decitabine 3.5717967635
MESH:D001749 Urinary Bladder Neoplasms decitabine 2.8219087683 17616700
MESH:D014581 Urticaria Acetaminophen 3.3310982225
MESH:D014604 Uveal Neoplasms decitabine 5.4317785578
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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