AutismKB 2.0

Annotation Detail for EXOC5


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Basic Information Top
Gene Symbol:EXOC5 ( DKFZp666H126,HSEC10,PRO1912,SEC10,SEC10L1,SEC10P )
Gene Full Name: exocyst complex component 5
Band: 14q22.3
Quick LinksEntrez ID:10640; OMIM: 604469; Uniprot ID:EXOC5_HUMAN; ENSEMBL ID: ENSG00000070367; HGNC ID: 10696
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Diabetes pathways
Pathway IDPathway Name
200012Insulin Pathway
200046Arf6 trafficking events
No data
Pathway IDPathway Name
500128Insulin Synthesis and Processing
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of EXOC5 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of EXOC5 mRNAdecreases expression 20018196
19150397
D005419 Flavonoids Flavonoids results in decreased expression of EXOC5 mRNAdecreases expression 18035473
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 3.0120889678
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1520426865
MESH:D007249 Inflammation Flavonoids 2.8417296493
Pathway ID Pathway Name
REACT:15380 Diabetes pathways
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA35619
  • No data
    No data
    Releated drug ID Related drug Name
    PA448976choline
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018