AutismKB 2.0

Annotation Detail for GNA13


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Basic Information Top
Gene Symbol:GNA13 ( G13,MGC46138 )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha 13
Band: 17q24.1
Quick LinksEntrez ID:10672; OMIM: 604406; Uniprot ID:GNA13_HUMAN; ENSEMBL ID: ENSG00000120063; HGNC ID: 4381
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04270Vascular smooth muscle contraction
hsa04730Long-term depression
hsa04810Regulation of actin cytoskeleton
Pathway IDPathway Name
Signaling by GPCR
Hemostasis
Pathway IDPathway Name
200035S1P3 pathway
200181S1P2 pathway
200083CXCR4-mediated signaling events
200011LPA receptor mediated events
200043S1P4 pathway
200104Sphingosine 1-phosphate (S1P) pathway
200029Plasma membrane estrogen receptor signaling
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
2237Neoplasm metastasis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C054649 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of GPR55 protein] affects the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 protein]affects binding|affects reaction|increases activity 17876302
D000082 Acetaminophen Acetaminophen affects the expression of GNA13 mRNAaffects expression 17562736
C005948 astaxanthine astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA]decreases reaction|increases expression 16964424
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of GNA13 mRNAincreases expression 20106945
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GNA13 mRNAdecreases expression 19150397
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GNA13 mRNAaffects expression 17484886
D004390 Chlorpyrifos Chlorpyrifos affects the expression of GNA13 mRNAaffects expression 17452286
C057862 cyanoginosin LR cyanoginosin LR results in increased expression of GNA13 mRNAincreases expression 17654400
D016572 Cyclosporine Cyclosporine results in increased expression of GNA13 mRNAincreases expression 20106945
D003976 Diazinon Diazinon affects the expression of GNA13 mRNAaffects expression 17452286
D004958 Estradiol Estradiol affects the expression of GNA13 mRNAaffects expression 15598610
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GNA13 mRNAdecreases expression 17475347
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GNA13 mRNAaffects cotreatment|increases expression 17942748
D016244 Guanosine 5'-O-(3-Thiotriphosphate) [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol binds to and results in increased activity of GPR55 protein] affects the reaction [Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 protein]affects binding|affects reaction|increases activity 17876302
D016244 Guanosine 5'-O-(3-Thiotriphosphate) Guanosine 5'-O-(3-Thiotriphosphate) binds to GNA13 proteinaffects binding 17876302
C051890 irinotecan irinotecan analog results in increased expression of GNA13 mRNAincreases expression 18927307
D010126 Ozone Ozone results in increased expression of GNA13 mRNAincreases expression 17095637
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GNA13 mRNAaffects cotreatment|increases expression 17942748
D014212 Tretinoin Tretinoin promotes the reaction [SPAG9 protein binds to GNA13 protein]affects binding|increases reaction 16619266
D014212 Tretinoin Tretinoin results in increased expression of GNA13 proteinincreases expression 16619266
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8411752688 15322242 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9417505938
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 6.9720127859 20464547
MESH:D000230 Adenocarcinoma Estradiol 6.9711473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 6.9714692618
MESH:D000236 Adenoma Benzo(a)pyrene 2.646695378
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.3716835633
MESH:D000382 Agricultural Workers' Diseases Chlorpyrifos 9.1411874814 16611668 17119214
MESH:D000382 Agricultural Workers' Diseases Diazinon 9.1416487989
MESH:D000505 Alopecia Tretinoin 3.6015955085
MESH:D000544 Alzheimer Disease Ozone 2.4315513908
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9311748828
MESH:D000799 Angioedema Acetaminophen 3.8410982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.0619183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 7.1615885639
MESH:D001169 Arthritis, Experimental Tretinoin 7.1616412693
MESH:D001172 Arthritis, Rheumatoid Ozone 4.6515570426
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.6516292516
MESH:D001249 Asthma Ozone 4.9317854713 16373670
MESH:D001249 Asthma Tretinoin 4.9316456186
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001471 Barrett Esophagus Tretinoin 4.3916935849
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.8812125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 8.8816206674 16197459
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7515746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9120146248 17474063
MESH:D001943 Breast Neoplasms Estradiol 1.9117289903 14630087 12948864 17261762 16675129 17018787 19861407 18497071
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9120435547
MESH:D001943 Breast Neoplasms Tretinoin 1.9116873071 16443354 16166294
MESH:D016535 Bronchial Hyperreactivity Ozone 3.6616777450 18315731 19059883 18417511 14754758 15516495 17626835
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.5816813970
MESH:D002100 Cachexia Ozone 4.7316183385
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.4516111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7710355542 15721981 3786805 16192424 16050911 15673190 16124888 16227642 16011737 15700767 16097048 18705752
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7816835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.1616168501
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.533084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 6.5318788625
MESH:D006528 Carcinoma, Hepatocellular Estradiol 6.5316924424
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 6.531917145
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 4.5520419170
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.5516096774 16051514
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3518670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 7.1810977129
MESH:D002386 Cataract Tretinoin 7.1817460283
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 11.0520889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.0512371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.0518566989
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.5816129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.1416835633
MESH:D002779 Cholestasis Cyclosporine 7.7219486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.7216105132 15861022 16919318 11677210 17681005 17333356 17110522
MESH:D002822 Choriocarcinoma Tretinoin 5.1616461808
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.7416354765 8697196 15668235 15340226 12621046
MESH:D002972 Cleft Palate Tretinoin 5.749407595
MESH:D003092 Colitis Tretinoin 3.6917035595
MESH:D003110 Colonic Neoplasms irinotecan 2.5917287894 17725105
MESH:D015179 Colorectal Neoplasms irinotecan 2.3616391804 15273666 17159606 17454858 18259882 18509181 16303861
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0417141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4420055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 2.449211117 10589399 14991402 17551590 9125849 16925845 9224671 9142499 9664655 8800419
MESH:D003924 Diabetes Mellitus, Type 2 astaxanthine 4.8616964424
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.8617107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.3919279558
MESH:D003967 Diarrhea 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 4.8710611417
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 8.9519370779 12705907 15619225 17522070 10663392 10915739 18713872 16081117 16485898 17906064 19420014 16227642 11529661 11421492 11743745 15968718 12392966 19085960 11739529 11287661 16393943 19416960 12153990 11834606 10774834 11461765 12540782 16109766 14550746 12958197 17562736 18071297 14986274 14725611 12594235 16781746 19164858 16177239 19923254 19739265 2444490
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 8.9516227642 21278145 19085960 7179309 4309450 6884620 2869522 6623471 9327722 15027814 15968718 19336974 7440962 3732212 10915739 10092053 17522070 15998439 16177239 3786805 11566570 7120509
MESH:D056486 Drug-Induced Liver Injury cyanoginosin LR 8.9517654400
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 8.9520420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.1019426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7411462148
MESH:D004417 Dyspnea Diazinon 4.8016487989
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 11.9518230668 15322242 16714409
MESH:D004489 Edema, Cardiac Tretinoin 11.9518230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.1712538720
MESH:D016889 Endometrial Neoplasms Estradiol 7.3711473722 18566989 19148513
MESH:D016889 Endometrial Neoplasms Tretinoin 7.3716569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.0010568697 9294722
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.3320426865
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 4.3316530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.7811564622
MESH:D005124 Eye Abnormalities Tretinoin 8.7816938888 9664655
MESH:D005234 Fatty Liver Carbon Tetrachloride 12.9519224547 12631006 16239168 12795759 16045604 15959796 61145 17595544
MESH:D005234 Fatty Liver Cyclosporine 12.9519224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 12.9515345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4411858732
MESH:D005355 Fibrosis Carbon Tetrachloride 21.0418705752
MESH:D005355 Fibrosis Cyclosporine 21.0412639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 21.0420067830
MESH:D005355 Fibrosis Tretinoin 21.0417994277
MESH:D005756 Gastritis Acetaminophen 3.6816983495
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.218708960
MESH:D005909 Glioblastoma Tretinoin 2.9917312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5910696789
MESH:D006258 Head and Neck Neoplasms Tretinoin 3.1716096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.1616084493
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 11.0320471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 11.0310048152 11294989
MESH:D006330 Heart Defects, Congenital Tretinoin 11.039664655 14991402
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.4115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3211000095
MESH:D006505 Hepatitis Carbon Tetrachloride 9.5619900420 19110552
MESH:D006505 Hepatitis Diazinon 9.5616487989
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8812621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.0315709030
MESH:D019584 Hot Flashes Estradiol 3.7517088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0515340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 7.5716870215
MESH:D006930 Hyperalgesia Tretinoin 7.5716870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5216899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.5516778211
MESH:D006973 Hypertension Cyclosporine 4.9210903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.9218670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0715338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8016945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4412013081
MESH:D007248 Infertility, Male Diazinon 6.9016466525 12948887
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.9017937319
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.8412878042 12200463
MESH:D007333 Insulin Resistance Estradiol 2.9516627594 16393666
MESH:D007410 Intestinal Diseases Tretinoin 3.7517994277
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 9.8716580747
MESH:D007569 Jaw Abnormalities Tretinoin 9.8715992940 17551590
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4415604871
MESH:D007674 Kidney Diseases Acetaminophen 9.9012587719 15629191
MESH:D007674 Kidney Diseases Cyclosporine 9.908314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 9.9015618244
MESH:D007680 Kidney Neoplasms Cyclosporine 7.2112371664
MESH:D007680 Kidney Neoplasms Estradiol 7.2115610895
MESH:D007938 Leukemia Tretinoin 2.7617143497
MESH:D007951 Leukemia, Myeloid Tretinoin 3.6819285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 2.0717596541 16294345 19850784
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.1416935935 17649720 19225113 16788101 17301526 16823087 16140955 17294898 12679006 9834237 19029980 17712046 17506722 19035177 17368321 16891316 16331271 17339181 16766008 19075265 15748426 17107899 17217047 17361223 19642359
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.299224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8011408273 21278145 16943688 16239168 11903743 17174718 16221502 17157831 17334410
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9218263696 12898905 18277467 15925388 14748882 16638106 16015684 17698563 15959796 15818738 18472332 18472094 14716833 17761835 11481614 17481882 16116963 12546737 16097048 12389079 12586293 15673190 15362042 15370692 18205269 17708605 15123356 14512876 15650968 17823541 18156304 18210741 18317297 12666154 18429990 12632514 15996030 18395914 18481824 16136751 13678700 15730626 17525996 12649538 18418968 12445418 18166357 14716496 18339082 15931870 17721639 18054572 15876570 17714472 17640975 16248980 12958196 18251166 15052691 18376398 14724832 17869086 12609069 14620537 20821823 17557913 16027843 18006644 18279442 17922224 17805973 18187930 18412020 17900296 17976157 12741479 16011737 12445421 12632512 10355542 17766677 17565644 16192424 17631135 15893842 16033810 18395095 15057751 12667390 18420326 18705752 17944888 15338365
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 4.9214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9212878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 4.9218397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 6.5719014921 12587719 11587558 16610002 19784758 16611625 19460945 12969438
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.5716246199 17285989 15830285 15720792 16964402
MESH:D008107 Liver Diseases Chlorpyrifos 6.5715991261
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.3516871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.3516899240 14706259
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 7.3220195826 21137059
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 7.3219294768
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 7.3216984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 5.7112014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 5.7112151625
MESH:D008171 Lung Diseases Ozone 3.3619066396 8266340
MESH:D055370 Lung Injury Ozone 3.8320417186
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.3820464547 6695378 18816296 20869020 18569708 20064080 18520028 20135361 17053015
MESH:D008175 Lung Neoplasms Ozone 3.387614698 8597069
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.3819555203 11884234
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.5411807958 16891317 11408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.4819453300
MESH:D008527 Medulloblastoma Tretinoin 2.7817453147
MESH:D008545 Melanoma Tretinoin 1.9416752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5519513568
MESH:D008591 Meningomyelocele Tretinoin 4.4116940565
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7916801185
MESH:D008679 Metaplasia Ozone 5.1110496685
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.1716381670
MESH:D052016 Mucositis irinotecan 5.0017159606
MESH:D009128 Muscle Spasticity 3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol 6.0917220914
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.0717596541
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.2616810080
MESH:D009362 Neoplasm Metastasis irinotecan 3.1618259882
MESH:D009369 Neoplasms Benzo(a)pyrene 4.9611141357
MESH:D009369 Neoplasms Tretinoin 4.9616594593 16946489
MESH:D009389 Neovascularization, Pathologic Estradiol 3.7217289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2719348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 16.2416427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 16.2414600291
MESH:D009421 Nervous System Malformations Tretinoin 16.249125849
MESH:D009436 Neural Tube Defects Tretinoin 3.049142499
MESH:D009447 Neuroblastoma irinotecan 3.478761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.8518514411
MESH:D017599 Neuroectodermal Tumors irinotecan 4.728761367
MESH:D020258 Neurotoxicity Syndromes Chlorpyrifos 4.1515081274
MESH:D010051 Ovarian Neoplasms Estradiol 4.7819401270
MESH:D010051 Ovarian Neoplasms Tretinoin 4.7816936753
MESH:D010146 Pain Acetaminophen 6.5316870215
MESH:D010146 Pain Tretinoin 6.5316870215
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6711578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2512520081
MESH:D010538 Peritonitis Ozone 4.1216369182
MESH:D011014 Pneumonia Ozone 4.3918929643 18007984 18381685
MESH:D011041 Poisoning Diazinon 4.3317603234
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5418163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.2012371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1811118676 11896295 11222880 11399792
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.8720887781
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1217292933
MESH:D011471 Prostatic Neoplasms Estradiol 3.1216740699
MESH:D011507 Proteinuria Tretinoin 3.5916636307
MESH:D011537 Pruritus Ethinyl Estradiol 3.3016919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2216882103
MESH:D011625 Pterygium Tretinoin 4.7816723453
MESH:D012135 Respiratory Sounds Chlorpyrifos 4.6211874814 16611668 17119214
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8218990726
MESH:D012140 Respiratory Tract Diseases Chlorpyrifos 4.8916611668 17119214
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.0816283617 16116481
MESH:D012729 Sex Chromosome Aberrations Chlorpyrifos 6.096418539
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 9.3310029692 19755658
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 9.3316192470
MESH:D012878 Skin Neoplasms Tretinoin 9.3316467112
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9416709447
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 3.402093021 20155912
MESH:D013274 Stomach Neoplasms irinotecan 3.4015723263
MESH:D013274 Stomach Neoplasms Tretinoin 3.4017261132
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1315669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.9012697716
MESH:D013964 Thyroid Neoplasms Tretinoin 3.0116026305 17045167
MESH:D013978 Tibial Fractures Estradiol 4.6919048282
MESH:D014062 Tongue Neoplasms Tretinoin 3.7716051514
MESH:D014376 Tuberculosis Tretinoin 3.2116040207
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.1717053015
MESH:D014570 Urologic Diseases Diazinon 5.2816487989
MESH:D014581 Urticaria Acetaminophen 2.9610982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.6616129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2814692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.6116752155
MESH:D014605 Uveitis Cyclosporine 3.981336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5215869587 14671159
MESH:D014820 Vitiligo Tretinoin 4.0416761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2515886252
MESH:D009396 Wilms Tumor Tretinoin 3.9516287080
MESH:D014985 Xerophthalmia Cyclosporine 4.4417120751
Pathway ID Pathway Name
REACT:604 Hemostasis
KEGG:04730 Long-term depression
KEGG:04810 Regulation of actin cytoskeleton
REACT:14797 Signaling by GPCR
KEGG:04270 Vascular smooth muscle contraction
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28766
    • No data
    Releated disease ID Related disease Name
    PA443450Asthma
    Releated drug ID Related drug Name
    PA448478l-arginine
    PA450635nitric oxide
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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