AutismKB 2.0

Annotation Detail for YME1L1


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Basic Information Top
Gene Symbol:YME1L1 ( FTSH,MEG4,PAMP,YME1L )
Gene Full Name: YME1-like 1 (S. cerevisiae)
Band: 10p12.1
Quick LinksEntrez ID:10730; OMIM: 607472; Uniprot ID:YMEL1_HUMAN; ENSEMBL ID: ENSG00000136758; HGNC ID: 12843
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of YME1L1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of YME1L1 mRNAaffects expression 16483693
D016572 Cyclosporine Cyclosporine results in increased expression of YME1L1 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of YME1L1 mRNAincreases expression 17108234
D009151 Mustard Gas Mustard Gas results in increased expression of YME1L1 mRNAincreases expression 15674844
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in increased expression of YME1L1 mRNAincreases expression 17616710
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.0218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.4617505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8714692618
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.8811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8415885639
MESH:D001249 Asthma Mustard Gas 2.7810378619
MESH:D001768 Blister Mustard Gas 5.6219167455
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 5.6215286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 5.5017687719 10378619
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.276135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.2712371664
MESH:D002779 Cholestasis Cyclosporine 8.5519486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.5515861022 11677210 17333356 16105132 17110522 17681005 16919318
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.4418551238
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0421346803 18551238
MESH:D004487 Edema Mustard Gas 3.639260866 11402378 11428631 11428647
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.5712538720
MESH:D004890 Erythema Mustard Gas 5.629357497
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.8416704527 16805852 15264214 15150132 16510608 15547733 15623463 15878914 15547721
MESH:D005234 Fatty Liver Cyclosporine 8.6819224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.6815345470
MESH:D005355 Fibrosis Cyclosporine 3.5612168785 12639820
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.688708960
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.8815720958
MESH:D006973 Hypertension Cyclosporine 2.1910903974
MESH:D007021 Hypospadias Ethinyl Estradiol 4.2316945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.8112013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6817937319
MESH:D007249 Inflammation Mustard Gas 2.928975870 11428631 17524151 11402378 9357497 11428620 9260866 16001271 11428647
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.9615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.5018776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.1816705839
MESH:D007680 Kidney Neoplasms Cyclosporine 8.1812371664
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.247678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.722876786 2876784 6135515
MESH:D008171 Lung Diseases Mustard Gas 3.6518702808 18161513
MESH:D008175 Lung Neoplasms Mustard Gas 2.178781369 3148597
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.3116801185
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.3218551238 7678174
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.9617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5719348381 18481113
MESH:D009503 Neutropenia Mustard Gas 4.3216761898 7688884
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7416049721
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.0411578682
MESH:D011041 Poisoning Mustard Gas 4.1515727166
MESH:D011230 Precancerous Conditions Cyclosporine 3.5112371664
MESH:D011537 Pruritus Ethinyl Estradiol 11.1116919318 15861022
MESH:D011537 Pruritus Mustard Gas 11.1118058305
MESH:D011565 Psoriasis Cyclosporine 2.3116882103
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0217894541 17720292 17266442 10334151 17620002
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7418551238
MESH:D012871 Skin Diseases Mustard Gas 2.7816961503 12880345 15451306
MESH:D013088 Spermatocele Ethinyl Estradiol 4.4616709447
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.3312958204 17575124
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.9711994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.4415669648
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3916049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.7810091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.6814692618
MESH:D014605 Uveitis Cyclosporine 4.501336536
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.8715869587 14671159
MESH:D014985 Xerophthalmia Cyclosporine 4.9617120751
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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