AutismKB 2.0

Annotation Detail for KIF1C


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Basic Information Top
Gene Symbol:KIF1C ( KIAA0706,LTXS1 )
Gene Full Name: kinesin family member 1C
Band: 17p13.2
Quick LinksEntrez ID:10749; OMIM: 603060; Uniprot ID:KIF1C_HUMAN; ENSEMBL ID: ENSG00000129250; HGNC ID: 6317
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of KIF1C mRNAincreases expression 16788091
D000643 Ammonium Chloride Ammonium Chloride affects the expression of KIF1C mRNAaffects expression 16483693
D004041 Dietary Fats Dietary Fats results in increased expression of KIF1C mRNAincreases expression 18042831
D005419 Flavonoids Flavonoids results in increased expression of KIF1C mRNAincreases expression 18035473
C041786 palm oil palm oil results in increased expression of KIF1C mRNAincreases expression 18042831
D012643 Selenium Selenium results in increased expression of KIF1C mRNAincreases expression 19244175
D014028 Tobacco Smoke Pollution Tobacco Smoke Pollution results in decreased expression of KIF1C mRNAdecreases expression 18087596
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.9518287403
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Tobacco Smoke Pollution 5.9715814487
MESH:D001161 Arteriosclerosis Dietary Fats 4.2515238619
MESH:D001172 Arthritis, Rheumatoid Tobacco Smoke Pollution 3.2319898480
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D002289 Carcinoma, Non-Small-Cell Lung Tobacco Smoke Pollution 3.5011212258
MESH:D002294 Carcinoma, Squamous Cell Tobacco Smoke Pollution 3.2711212258
MESH:D003092 Colitis Selenium 4.1417936198
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2315131321
MESH:D050171 Dyslipidemias Dietary Fats 3.6518367378
MESH:D005234 Fatty Liver Dietary Fats 3.5217967931 18296743 19004024 19551842
MESH:D005355 Fibrosis Dietary Fats 3.8818296743
MESH:D006333 Heart Failure Selenium 3.2317162251
MESH:D006937 Hypercholesterolemia Dietary Fats 3.8721332399
MESH:D006949 Hyperlipidemias Dietary Fats 3.9221332399
MESH:D007249 Inflammation Dietary Fats 9.2820412841
MESH:D007249 Inflammation Flavonoids 9.2817296493
MESH:D007249 Inflammation Tobacco Smoke Pollution 9.2818590791
MESH:D007251 Influenza, Human Selenium 4.6416624496
MESH:D007333 Insulin Resistance Dietary Fats 3.2711836018 18457598
MESH:D007676 Kidney Failure, Chronic Selenium 4.1716518626
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0118296743
MESH:D008175 Lung Neoplasms Tobacco Smoke Pollution 2.723440675 11091918 12111688 16288123
MESH:D008325 Mammary Neoplasms, Experimental Selenium 2.9215318939
MESH:D008654 Mesothelioma Selenium 2.8815107826
MESH:D009062 Mouth Neoplasms Tobacco Smoke Pollution 4.5615006635
MESH:D009765 Obesity Dietary Fats 2.3420518802 17217161 18674790 19632207 20132043 21332399 16723640 18457598 11836018
MESH:D010954 Plasmacytoma Selenium 5.3315087411
MESH:D012135 Respiratory Sounds Tobacco Smoke Pollution 4.9818410779
MESH:D012878 Skin Neoplasms Tobacco Smoke Pollution 3.6418590791
MESH:D001749 Urinary Bladder Neoplasms Tobacco Smoke Pollution 3.4212846360
MESH:D015430 Weight Gain Dietary Fats 3.9916723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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