AutismKB 2.0

Annotation Detail for ZMYND11


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Basic Information Top
Gene Symbol:ZMYND11 ( BRAM1,BS69,MGC111056 )
Gene Full Name: zinc finger, MYND domain containing 11
Band: 10p15.3
Quick LinksEntrez ID:10771; OMIM: 608668; Uniprot ID:ZMY11_HUMAN; ENSEMBL ID: ENSG00000015171; HGNC ID: 16966
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZMYND11 mRNAdecreases expression 19150397
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ZMYND11 mRNAaffects cotreatment|affects expression 17602206
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ZMYND11 mRNAaffects cotreatment|affects expression 17602206
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of ZMYND11 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of ZMYND11 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of ZMYND11 mRNAaffects cotreatment|decreases expression 17942748
D007657 Ketone Bodies Ketone Bodies results in increased expression of ZMYND11 mRNAincreases expression 16807920
D012402 Rotenone Rotenone results in increased expression of ZMYND11 mRNAincreases expression 19013527
D018038 Sodium Selenite Sodium Selenite results in increased expression of ZMYND11 mRNAincreases expression 18175754
D013629 Tamoxifen Tamoxifen affects the expression of ZMYND11 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of ZMYND11 mRNAaffects cotreatment|decreases expression 17942748
D002762 Cholecalciferol Cholecalciferol results in increased expression of ZMYND11 mRNAincreases expression 16508948
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.8114745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0811752688 14514962 15322242
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.2117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8514692618
MESH:D000236 Adenoma Diethylnitrosamine 2.946695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 10.8618056438 19061943 17162532 16434500 17620307 19052882
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.8616835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1111748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.6811256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7615885639
MESH:D001327 Autoimmune Diseases Cholecalciferol 5.2416142846
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2112125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8715746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.8217474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.8216273361 17893378 20135344 19189212 19142967 21152245 18629630 17261762 19155303 15565566 16202921 19288272 19103187 18821012 19059307 18997820 19244106 17440819 11161223 16873071 19011961 18815881 20065188 19115204 18351453 19487384 19084267 18984771 18425577 20005174 18855134 15668708 20859285 20544844 17242785 19410462 19221464 20390343 19289846 16818667 19066611 21138602 17049068 19189210 19200415
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8220435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9316835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.7219066611
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.0819539802 19418558 3581430 16328049 20524982 17055752 19701751 20935162 20007298 17138121 19519916 20514400 19335982 16502159 19394651 19171122 19822196 3084413 18785209 18506893 20084675 17428255 21159647 18788625 16779866 18494052 16807293 16698587 18393292 16681979 11831363 17162532 18978308 16569478 19052882 17978847 16540662 20727157 19107877 20101231 10672840 16935385 17761372 18665156 16878318 16288022 17173139 10737359 19208518 20432363 19919837 19383236 18691550 20214788 16830150 18210153 20512989 18056438 18971187
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 3.0816924424
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.7817572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4516120746 18850075 18670907
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.0620889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.0621159647 7505956 17174075 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.8419052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.8416835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0017333356 17110522 17681005 16105132 15861022 16919318 11677210
MESH:D019457 Chromosome Breakage Sodium Selenite 4.9715894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1612621046 15340226 8697196 15668235 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2117141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2620055451 15322242 10048152
MESH:D003711 Demyelinating Diseases Tamoxifen 4.5819031437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.9316285004
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.3420387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3417107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.6319279558
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 6.4819107877
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.4815131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.4820420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8911462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5512711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.1715322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.6212538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.6219031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.1520544844 16202921 17893378 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.189294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.3816302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1120426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1411564622
MESH:D005234 Fatty Liver Diethylnitrosamine 14.1220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.1215345470
MESH:D005234 Fatty Liver Tamoxifen 14.1214986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.3316709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6711858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.7614745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.4219069698
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.1620067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8610696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4110048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5111000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.1115340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.3116354765 15340226 18606429 16959395 8697196
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9618670907 18850075
MESH:D007021 Hypospadias Ethinyl Estradiol 4.0216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6512013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5917937319
MESH:D007249 Inflammation Diethylnitrosamine 8.7518785209
MESH:D007249 Inflammation Tamoxifen 8.7519457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.7512878042 12200463
MESH:D007333 Insulin Resistance Sodium Selenite 3.3814714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5116580747
MESH:D007680 Kidney Neoplasms Tamoxifen 3.1918625569
MESH:D008064 Lipidoses Tamoxifen 3.2717567588 15342952
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9118665156 20032147 18522880 19638242 18407596
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 2.3318564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3312878042
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1317034775
MESH:D008113 Liver Neoplasms Clofibric Acid 11.2017602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 11.2020492335 19850985 21047994 19294768 19427195 18977376 19073162 12112319 10737359 21071580 16942905 19996281 19426721 18754104 20405173 19638242 19690152 21167192 15885732 19256749 20501860 19090486 20137499 12771043 18644402 19642983 20118626 19254457 19812893 19551842 9163691 20452335 20583210 2862719 19499222 19833225 20434301 19255062 18978307 21278145 15175105 2422723 18648771 20101389
MESH:D008113 Liver Neoplasms Tamoxifen 11.2016684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.2016984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.1018253720 19519916 18093689 9362446 18164116 16267830 17942915 19009564 19126423 2563599 3124819 16842330 18775883 21159647 18544905 18308698 18079962 18282651 19004024 19539802 17854601 17174075
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.1012151625
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.4621163286 20970405 6695378 20512841
MESH:D008175 Lung Neoplasms Tamoxifen 3.4618625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.4611884234 19555203
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.2414737004
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 4.0019428831
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 2.7319196723 16827153 14580682 19196722 11731420
MESH:D020149 Manganese Poisoning Tamoxifen 4.8119453300
MESH:D008545 Melanoma Tamoxifen 1.9019393235 12393984
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.4215990972
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1612213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.933581430 9029167
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.9319393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5619410462
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.2619189210 19200415 19196722
MESH:D009410 Nerve Degeneration Rotenone 4.0118619942 15790535 17356569
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4114600291
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.4820387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.3820387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4716540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.8711578682
MESH:D010300 Parkinson Disease Rotenone 3.0318619942 19232380 16412576 16140633 11445065 18191903 15451049 19114014 11535288
MESH:D020734 Parkinsonian Disorders Rotenone 4.2415574749 18197244 15795934 15927086
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.5112520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7618163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.702563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.4311399792 11118676 11222880 11896295
MESH:D011471 Prostatic Neoplasms Cholecalciferol 2.6817024972
MESH:D011471 Prostatic Neoplasms Sodium Selenite 2.6818760546
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.6815067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.5516919318 15861022
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0418990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1116192470
MESH:D013088 Spermatocele Ethinyl Estradiol 12.4616709447
MESH:D013088 Spermatocele Tamoxifen 12.4616709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.2819457130
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8011994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.1712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.117505956
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 2.418653321 17572228 16712894
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5014692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7114671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.5115886252
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA128394578
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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