AutismKB 2.0

Annotation Detail for ZNF268


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Basic Information Top
Gene Symbol:ZNF268 ( HZF3,MGC126498 )
Gene Full Name: zinc finger protein 268
Band: 12q24.33
Quick LinksEntrez ID:10795; OMIM: 604753; Uniprot ID:ZN268_HUMAN; ENSEMBL ID: ENSG00000090612; HGNC ID: 13061
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D011374 Progesterone Progesterone results in increased expression of ZNF268 mRNAincreases expression 18070364
D018038 Sodium Selenite Sodium Selenite results in increased expression of ZNF268 mRNAincreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D020201 Brain Hemorrhage, Traumatic Progesterone 6.4117868700
MESH:D001930 Brain Injuries Progesterone 5.0215665606 15845082 15380490
MESH:D001943 Breast Neoplasms Progesterone 2.4016175315 15562024 17614352
MESH:D019457 Chromosome Breakage Sodium Selenite 5.5215894690
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.2516285004
MESH:D003929 Diabetic Neuropathies Progesterone 5.2617187935
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 2.3815131321
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Progesterone 4.4517692515
MESH:D004715 Endometriosis Progesterone 4.2716134523
MESH:D020244 Infarction, Middle Cerebral Artery Progesterone 5.1715869954
MESH:D007249 Inflammation Progesterone 2.8115869954
MESH:D007333 Insulin Resistance Sodium Selenite 3.5714714311
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.6614737004
MESH:D008325 Mammary Neoplasms, Experimental Progesterone 3.1517203775 11408345
MESH:D010051 Ovarian Neoplasms Progesterone 2.6316525653 17393432
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.3218760546
MESH:D012468 Salivary Gland Neoplasms Progesterone 2.9818045962
MESH:D013119 Spinal Cord Injuries Progesterone 5.1715862959 16503802
Pathway ID Pathway Name
REACT:71 Gene Expression
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018