AutismKB 2.0

Annotation Detail for HSPH1


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Basic Information Top
Gene Symbol:HSPH1 ( DKFZp686M05240,HSP105,HSP105A,HSP105B,KIAA0201,NY-CO-25 )
Gene Full Name: heat shock 105kDa/110kDa protein 1
Band: 13q12.3
Quick LinksEntrez ID:10808; OMIM: 610703; Uniprot ID:HS105_HUMAN; ENSEMBL ID: ENSG00000120694; HGNC ID: 16969
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04141Protein processing in endoplasmic reticulum
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of HSPH1 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of HSPH1 mRNAaffects expression 21346803
C019499 2-nitrofluorene 2-nitrofluorene results in increased expression of HSPH1 mRNAincreases expression 15890375
C026137 3-hydroxyacetanilide 3-hydroxyacetanilide results in decreased expression of HSPH1 mRNAdecreases expression 18544908
C035207 4-amino-2,6-dinitrotoluene 4-amino-2,6-dinitrotoluene affects the expression of HSPH1 mRNAaffects expression 21346803
C016583 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of HSPH1 mRNAincreases expression 15890375
C075773 4-phenylbutyric acid 4-phenylbutyric acid results in increased expression of HSPH1 mRNAincreases expression 14583596
D000082 Acetaminophen Acetaminophen results in increased expression of HSPH1 mRNAincreases expression 11264010
12958197
18544908
11743745
D000082 Acetaminophen PPARA protein affects the reaction [Acetaminophen results in increased expression of HSPH1 mRNA]affects reaction|increases expression 12958197
D000082 Acetaminophen PTGS2 protein affects the reaction [Acetaminophen results in increased expression of HSPH1 mRNA]affects reaction|increases expression 11743745
D000082 Acetaminophen Acetaminophen results in increased expression of HSPH1 mRNAincreases expression 17202762
D016604 Aflatoxin B1 Aflatoxin B1 results in decreased expression of HSPH1 mRNAdecreases expression 15890375
C103303 alitretinoin alitretinoin results in decreased expression of HSPH1 mRNAdecreases expression 16648578
D003913 Dextroamphetamine Dextroamphetamine results in increased expression of HSPH1 mRNAincreases expression 12558987
C006632 arsenic trioxide arsenic trioxide results in increased expression of HSPH1 mRNAincreases expression 17530438
19417148
D016589 Astemizole Astemizole results in decreased expression of HSPH1 mRNAdecreases expression 20221588
C095105 bexarotene bexarotene results in decreased expression of HSPH1 mRNAdecreases expression 16648578
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of HSPH1 mRNAdecreases expression 15336504
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of HSPH1 mRNAincreases expression 15056808
D016572 Cyclosporine Cyclosporine results in increased expression of HSPH1 mRNAincreases expression 20106945
D013759 Tetrahydrocannabinol Tetrahydrocannabinol results in decreased expression of HSPH1 mRNAdecreases expression 16039398
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of HSPH1 mRNAincreases expression 15890375
D004128 Dimethylnitrosamine Dimethylnitrosamine results in increased expression of HSPH1 mRNAincreases expression 15890375
D004317 Doxorubicin DMD protein affects the reaction [Doxorubicin results in decreased expression of HSPH1 mRNA]affects reaction|decreases expression 17888722
D004317 Doxorubicin Doxorubicin results in decreased expression of HSPH1 mRNAdecreases expression 17888722
D004958 Estradiol Estradiol results in increased expression of HSPH1 mRNAincreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of HSPH1 mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of HSPH1 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPH1 mRNAaffects cotreatment|increases expression 17942748
C106014 gedunin gedunin results in increased expression of HSPH1 mRNAincreases expression 17010675
D019833 Genistein Genistein results in increased expression of HSPH1 mRNAincreases expression 17341692
C027185 indirubin indirubin results in decreased expression of HSPH1 mRNAdecreases expression 15056799
D008701 Methapyrilene Methapyrilene results in increased expression of HSPH1 mRNAincreases expression 15890375
C002950 methylformamide methylformamide analog results in increased expression of HSPH1 mRNAincreases expression 17040096
C002950 methylformamide methylformamide results in increased expression of HSPH1 mRNAincreases expression 17040096
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of HSPH1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in decreased expression of HSPH1 mRNAdecreases expression 19270015
D010634 Phenobarbital Phenobarbital results in increased expression of HSPH1 mRNAincreases expression 19482888
19270015
D010882 Piperonyl Butoxide Piperonyl Butoxide results in increased expression of HSPH1 mRNAincreases expression 15890375
C006253 pirinixic acid pirinixic acid results in decreased expression of HSPH1 mRNAdecreases expression 17426115
C006253 pirinixic acid pirinixic acid results in increased expression of HSPH1 mRNAincreases expression 20059764
C006253 pirinixic acid pirinixic acid results in increased expression of HSPH1 proteinincreases expression 20059764
C006253 pirinixic acid PPARA protein affects the reaction [pirinixic acid results in increased expression of HSPH1 mRNA]affects reaction|increases expression 20059764
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in increased expression of HSPH1 protein]increases expression|increases reaction 20059764
C006253 pirinixic acid pirinixic acid results in increased expression of HSPH1 mRNAincreases expression 15890375
C009166 retinol acetate retinol acetate results in increased expression of HSPH1 mRNAincreases expression 16772331
C064116 S-(1,1,2,2-tetrafluoroethyl)cysteine S-(1,1,2,2-tetrafluoroethyl)cysteine results in increased expression of HSPH1 mRNAincreases expression 16678137
C515055 S-(dimethylarsino)-glutathione S-(dimethylarsino)-glutathione results in increased expression of HSPH1 mRNAincreases expression 19417148
C017947 sodium arsenite sodium arsenite results in increased expression of HSPH1 mRNAincreases expression 18812580
D013629 Tamoxifen Tamoxifen affects the expression of HSPH1 mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of HSPH1 mRNAdecreases expression 15056799
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HSPH1 mRNAaffects cotreatment|increases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSPH1 mRNAincreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of HSPH1 mRNAincreases expression 16960034
C050414 tripterine tripterine results in increased expression of HSPH1 mRNAincreases expression 17010675
D001335 Vehicle Emissions Vehicle Emissions results in increased expression of HSPH1 mRNAincreases expression 19465080
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.1314745880
MESH:D000014 Abnormalities, Drug-Induced 4-amino-2,6-dinitrotoluene 11.917525203
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 11.916195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 11.9115322242 11752688 14514962
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.5317505938
MESH:D055371 Acute Lung Injury pirinixic acid 2.7518653653
MESH:D000230 Adenocarcinoma arsenic trioxide 15.5819825857 11798837
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 15.5816033868
MESH:D000230 Adenocarcinoma Doxorubicin 15.5817418594
MESH:D000230 Adenocarcinoma Estradiol 15.5811473722
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 15.5814692618
MESH:D000230 Adenocarcinoma Genistein 15.5811473722
MESH:D000236 Adenoma 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 6.5316176798
MESH:D000236 Adenoma Dimethylnitrosamine 6.5319555203
MESH:D018248 Adenoma, Liver Cell Phenobarbital 14.9317620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 14.9316434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 14.9316835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.2815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.4917306315 16712894
MESH:D000419 Albuminuria Doxorubicin 4.1621441931
MESH:D000686 Amyloidosis Diethylstilbestrol 4.0915469931
MESH:D000690 Amyotrophic Lateral Sclerosis Tetrahydrocannabinol 4.5815204022
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6011748828
MESH:D000799 Angioedema Acetaminophen 10.6510982225
MESH:D000799 Angioedema Astemizole 10.652883202
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.0711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.4115885639
MESH:D050197 Atherosclerosis Tetrahydrocannabinol 4.2315815632
MESH:D001321 Autistic Disorder Acetaminophen 1.4618445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 13.1816206674
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.1819483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.1812125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.3815340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5015746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.2814601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.4617150277
MESH:D001943 Breast Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 5.3620146248
MESH:D001943 Breast Neoplasms alitretinoin 5.3616344269
MESH:D001943 Breast Neoplasms bexarotene 5.3616818667 16344269
MESH:D001943 Breast Neoplasms Diethylstilbestrol 5.3615324884 17129689
MESH:D001943 Breast Neoplasms Doxorubicin 5.3618382427 18628466 16935488 19526202 17426702 15939500 15567936 18695136 16826403 16115903 11325840 16264153 15634643 15136595 15993339 16096432 16595493 18234424 17983394 16322301 15692762 17369602 15994142 15668708
MESH:D001943 Breast Neoplasms Estradiol 5.3614630087 16675129 12948864 18497071 17289903 17018787 19861407 17261762
MESH:D001943 Breast Neoplasms Genistein 5.3616873071 16541309 17200150
MESH:D001943 Breast Neoplasms Tamoxifen 5.3620065188 17893378 16273361 19011961 19066611 18815881 19103187 20544844 19487384 19142967 20005174 19189212 21138602 18629630 16873071 15565566 17049068 19155303 19410462 19084267 17440819 18855134 21152245 16202921 20859285 19115204 17242785 19189210 20390343 19221464 19288272 15668708 18984771 18351453 19244106 11161223 18425577 20135344 19289846 19200415 19059307 18821012 16818667 18997820 17261762
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 5.3620435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.9511589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.0616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.3816050911 15673190 16124888 15721981 16097048 16227642 18705752 15700767 10355542 3786805 16192424 16011737
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4016051944
MESH:D002277 Carcinoma Dimethylnitrosamine 7.2919555203
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 7.2916835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.1119066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 30.6416705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 30.6416705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 30.643084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 30.6421507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 30.6411135700 16217749 15553829 14691202 15073043
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 30.6418788625
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 30.6416924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 30.6416234567 18059187 16023760 17876044
MESH:D006528 Carcinoma, Hepatocellular Estradiol 30.6416924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 30.6416924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 30.6417173139 1701930 20007298 6705139 20935162
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 30.6415276417 17306315 16507464
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 30.6416924424
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.0816247446
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.4619014326
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 2.9616201981 1485588
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.7612490120
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 6.9016033868
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 6.906189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 6.9018572023
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.2617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.1418850075 18670907 16120746
MESH:D009202 Cardiomyopathies Doxorubicin 3.2615792986 17519947 17382496 16651473 17928571 17329180 16455267 17131338 15811867 16731534 16242529 16109756 16278810 15505089 17974986 15476868 16952015 17308081 17924179 17351982 16612575 16269455 17007740 16364871 18627295
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8017334414 16243910
MESH:D002318 Cardiovascular Diseases Genistein 3.0216332659
MESH:D002375 Catalepsy Tetrahydrocannabinol 5.3210318961
MESH:D002386 Cataract 4-amino-2,6-dinitrotoluene 6.6114694615
MESH:D002386 Cataract Acetaminophen 6.6110977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 13.696135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 13.6912371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 13.6918566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 13.6919524636 20056578
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.854080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8216835633
MESH:D002779 Cholestasis Cyclosporine 11.6019486331
MESH:D002779 Cholestasis Ethinyl Estradiol 11.6016919318 15861022 17681005 17333356 16105132 11677210 17110522
MESH:D002779 Cholestasis pirinixic acid 11.6019176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 1.9315668235 15340226 16354765 8697196 12621046
MESH:D003110 Colonic Neoplasms Genistein 2.2217182828
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.4920501625
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.4918802399 18259882
MESH:D000013 Congenital Abnormalities 4-amino-2,6-dinitrotoluene 8.0515095906
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.0514669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 3.8012609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.3310525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.3310048152 15322242 20055451
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.1716002989 12952375
MESH:D003490 Cyanosis 2,4-dinitrotoluene 9.5718551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 9.5718551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.7215213294
MESH:D003711 Demyelinating Diseases Tamoxifen 3.9619031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2318249437
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 3.9516647724
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 3.9517107852
MESH:D003928 Diabetic Nephropathies Estradiol 7.7119279558
MESH:D003928 Diabetic Nephropathies Tamoxifen 7.7119279558
MESH:D004244 Dizziness Astemizole 6.053105558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 19.8318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 19.8318551238 21346803
MESH:D056486 Drug-Induced Liver Injury 4-amino-2,6-dinitrotoluene 19.8321346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 19.8310774834 17906064 17562736 15968718 12392966 11287661 16485898 14986274 18713872 10915739 19370779 18071297 11739529 11461765 16081117 11834606 12540782 16227642 11529661 17522070 14550746 14725611 19164858 11421492 12153990 16781746 12594235 19739265 19923254 12705907 19420014 19416960 10663392 16109766 16393943 16177239 2444490 19085960 11743745 12958197 15619225
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 19.837440962 17522070 10915739 6623471 16177239 6884620 9327722 19336974 19085960 7120509 15968718 10092053 16227642 7179309 2869522 15027814 4309450 15998439 21278145 11566570 3732212 3786805
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 19.838172417
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 19.8317416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 19.8320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.6819426721
MESH:D004362 Drug Toxicity Doxorubicin 7.1118602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.1111462148
MESH:D004421 Dystonia Phenobarbital 3.631851702
MESH:D004487 Edema pirinixic acid 5.3612083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 5.3611000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.4918230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 7.6712538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 7.6719031437
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.5416402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.5416402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 20.4916804899 15700306
MESH:D016889 Endometrial Neoplasms Doxorubicin 20.4917359293
MESH:D016889 Endometrial Neoplasms Estradiol 20.4918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 20.4911473722
MESH:D016889 Endometrial Neoplasms Tamoxifen 20.4916202921 17893378 19155303 20544844
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.679294722 10568697
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.7418037988
MESH:D004802 Eosinophilia Astemizole 4.411355641
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.713659116
MESH:D004828 Epilepsies, Partial Phenobarbital 3.463922381 11558140
MESH:D004827 Epilepsy Phenobarbital 6.5120417680
MESH:D004827 Epilepsy Tetrahydrocannabinol 6.51821787
MESH:D004832 Epilepsy, Absence Phenobarbital 3.206401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.857750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.613659116
MESH:D004938 Esophageal Neoplasms arsenic trioxide 4.3712903497
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 4.3717016578
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.7111564622
MESH:D005234 Fatty Liver arsenic trioxide 26.0015073043
MESH:D005234 Fatty Liver Carbon Tetrachloride 26.0012795759 16239168 15959796 16045604 12631006 19224547 61145 17595544
MESH:D005234 Fatty Liver Cyclosporine 26.0019224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 26.0015345470
MESH:D005234 Fatty Liver pirinixic acid 26.0020131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 26.0019224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 7.3716002989 16611131 16534752 16513791 15751030
MESH:D052776 Female Urogenital Diseases Tamoxifen 7.3716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.0611858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.1214745880
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 10.0919069698
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 10.0919069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.4218705752
MESH:D005355 Fibrosis Cyclosporine 12.4212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.4220067830
MESH:D005499 Folliculitis Astemizole 5.501671328
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.8816904648
MESH:D005756 Gastritis Acetaminophen 3.2616983495
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.4616452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.4616452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.818708960
MESH:D005909 Glioblastoma Doxorubicin 6.4417150277
MESH:D005909 Glioblastoma Genistein 6.4416598420
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.1810696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 3.2515692506
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.1110048152 11294989
MESH:D006331 Heart Diseases Doxorubicin 3.2017888722 16879835 12587719 17875725 16330681 18006777 16144979 16495754 16707910 14766674 16244372 18674790 16244371
MESH:D006333 Heart Failure Doxorubicin 6.2017481944
MESH:D006333 Heart Failure pirinixic acid 6.2020558911
MESH:D006394 Hemangiosarcoma Doxorubicin 3.5415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 2.9711000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2119900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 12.0916109766
MESH:D006529 Hepatomegaly pirinixic acid 12.0918467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 12.0915340226 12621046 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.6215709030
MESH:D006689 Hodgkin Disease Doxorubicin 6.3618501091 17606976 15147373
MESH:D006689 Hodgkin Disease sodium arsenite 6.3612676792
MESH:D019584 Hot Flashes Estradiol 3.3417088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.6315340226 18606429 8697196 16959395 16354765
MESH:D006930 Hyperalgesia Acetaminophen 2.3816870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.1216899240
MESH:D006943 Hyperglycemia pirinixic acid 2.8320558911
MESH:D006965 Hyperplasia Diethylstilbestrol 4.0414722030 12960047
MESH:D006968 Hypersensitivity, Delayed indirubin 5.5211275354
MESH:D006973 Hypertension Cyclosporine 4.3910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.3918670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.6915338365
MESH:D007021 Hypospadias Diethylstilbestrol 9.9216002989
MESH:D007021 Hypospadias Ethinyl Estradiol 9.9216569931 16945680
MESH:D007035 Hypothermia Tetrahydrocannabinol 5.5310318961
MESH:D007246 Infertility Diethylstilbestrol 3.9715036965
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.0912013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 5.7317937319
MESH:D007248 Infertility, Male sodium arsenite 5.7312646999 15346721
MESH:D007249 Inflammation Tamoxifen 4.1719457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.1712878042 12200463
MESH:D007333 Insulin Resistance Estradiol 6.3016627594 16393666
MESH:D007333 Insulin Resistance pirinixic acid 6.3016306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 2.9716580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.0315604871
MESH:D017492 Keratosis, Seborrheic alitretinoin 5.2316144296
MESH:D007674 Kidney Diseases Acetaminophen 16.4915629191 12587719
MESH:D007674 Kidney Diseases Cyclosporine 16.4918776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 16.4916775033 15699352 15369732
MESH:D007674 Kidney Diseases Estradiol 16.4915618244
MESH:D007674 Kidney Diseases sodium arsenite 16.4920008137
MESH:D007676 Kidney Failure, Chronic Doxorubicin 3.7916707910
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 24.8316705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 24.8316705839
MESH:D007680 Kidney Neoplasms Cyclosporine 24.8312371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 24.8315003126 14681315 16762066
MESH:D007680 Kidney Neoplasms Estradiol 24.8315610895
MESH:D007680 Kidney Neoplasms Tamoxifen 24.8318625569
MESH:D007859 Learning Disorders Diethylstilbestrol 3.6717184923
MESH:D007938 Leukemia arsenic trioxide 5.7315070760
MESH:D007938 Leukemia Genistein 5.7318980019 17468513
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.7416085563
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.4317077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.9016972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.1314633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.4019077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.0716467208 20471514 17050201 19850784 16968895
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.9512712474 15622746 16823087 16966277 15213294 17217047 19035177 12679006 17712046 16331271 19642359 19225113 16891316 16330433 19075265 17869043 17107899 15336539 17649720 12018890 9834237 15748426 11468182 11161223 16112521
MESH:D015458 Leukemia, T-Cell arsenic trioxide 3.9716882451
MESH:D017513 Lichen Nitidus Astemizole 6.052563723
MESH:D008064 Lipidoses Tamoxifen 2.8717567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 5.8616943688 16239168 11408273 16221502 17334410 21278145 11903743 17157831 17174718
MESH:D008103 Liver Cirrhosis Phenobarbital 5.8621047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.1718472332 17721639 12898905 15893842 12445418 18279442 15370692 16192424 18277467 18317297 12389079 16027843 17761835 17631135 12632514 18339082 18412020 15959796 15673190 15996030 18395914 18429990 17714472 18156304 16015684 14716833 17481882 18263696 15925388 18418968 18472094 16011737 18251166 16116963 14748882 17525996 12666154 12667390 14512876 17640975 12546737 15876570 17805973 12741479 14620537 17766677 16136751 12609069 14716496 18395095 17823541 12445421 18376398 12632512 17708605 15362042 17698563 18420326 18210741 13678700 16638106 18205269 15818738 12586293 15931870 15052691 16248980 17565644 17869086 15123356 18006644 17976157 18054572 15650968 15730626 18187930 17922224 10355542 15338365 12958196 17557913 14724832 12649538 16033810 17900296 11481614 20821823 15057751 16097048 18166357 17944888 18481824 18705752
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 12.1717640959 15723089 15492853 15161499 17881167 16570917 16042886 17203207 18237412 15591649 15842777 16627068 15138612 18629640 15298665 15504291 14709902 15383259 15571005 15369754 15099470 16169303 15733078 14568256 15339415 15793283 17196135 18567088 15942678 17724770 15864749 17198567 17036385 15744066 16603200 15798949 15067225 18637143 15086199 17201889 18095165 15577212 15366600 14643895 16544323 17534399 18210741 14726149 17465448 18239293 14659978 16009107 18371158 17432682 12925901 12918455 15081153 18364076 15763062 18672772 17666798 15479170 16270385 17348192 17719030
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 12.1716595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 12.1714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 12.1717823541
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.1715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 12.1718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.1712878042
MESH:D008107 Liver Diseases Acetaminophen 5.7812969438 12587719 19784758 16611625 19014921 11587558 19460945 16610002
MESH:D008107 Liver Diseases Carbon Tetrachloride 5.7815720792 17285989 16246199 15830285 16964402
MESH:D008107 Liver Diseases Phenobarbital 5.7819363144
MESH:D017093 Liver Failure Carbon Tetrachloride 3.7715123358
MESH:D017114 Liver Failure, Acute Acetaminophen 14.2317185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 14.2314706259 16899240
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 14.2317457977
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 52.187678174
MESH:D008113 Liver Neoplasms 2-nitrofluorene 52.1815890375
MESH:D008113 Liver Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 52.1815890375
MESH:D008113 Liver Neoplasms Aflatoxin B1 52.1818177683 9163691 15890375 2125692
MESH:D008113 Liver Neoplasms arsenic trioxide 52.1814682389
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 52.1819294768
MESH:D008113 Liver Neoplasms Diethylstilbestrol 52.1816712894 15890375
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 52.1815890375 3113478
MESH:D008113 Liver Neoplasms Methapyrilene 52.1815890375
MESH:D008113 Liver Neoplasms Phenobarbital 52.1819812893 8742319 19073162 19482888 21047994 15975961
MESH:D008113 Liver Neoplasms Piperonyl Butoxide 52.1820101389 18648771 15890375 19690152
MESH:D008113 Liver Neoplasms pirinixic acid 52.1815890375 20007298 16377806
MESH:D008113 Liver Neoplasms sodium arsenite 52.1816712894 15276417
MESH:D008113 Liver Neoplasms Tamoxifen 52.1816684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 52.1816984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 28.752876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 28.758603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 28.7520377131
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 28.7512014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 28.751848544 15603536 6150874
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 28.7517085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 28.7517172636 6150874 1399818 18308698 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 28.7512151625
MESH:D008133 Long QT Syndrome arsenic trioxide 7.5415213294
MESH:D008133 Long QT Syndrome Astemizole 7.5411989578 18472280
MESH:D008171 Lung Diseases sodium arsenite 2.9019095001
MESH:D008175 Lung Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 19.1119931552 18813816 15893417 16401635 18508827 15172992 14755239 12438228 16061637 9255578 17139156
MESH:D008175 Lung Neoplasms Aflatoxin B1 19.1114755239
MESH:D008175 Lung Neoplasms alitretinoin 19.1116413115
MESH:D008175 Lung Neoplasms arsenic trioxide 19.1119825857 11798837
MESH:D008175 Lung Neoplasms bexarotene 19.1117849452
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 19.1111884234 16061637 19555203
MESH:D008175 Lung Neoplasms Doxorubicin 19.1117418594 6189445
MESH:D008175 Lung Neoplasms sodium arsenite 19.1117306315 17077188 16712894 19931552 15276417
MESH:D008175 Lung Neoplasms Tamoxifen 19.1118625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 19.1119555203 11884234
MESH:D008175 Lung Neoplasms Vehicle Emissions 19.119255578
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.7415166399
MESH:D008223 Lymphoma Diethylstilbestrol 6.7815700306
MESH:D008223 Lymphoma Doxorubicin 6.7816098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.4617654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.1715621674
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 4.7511161223
MESH:D008288 Malaria Astemizole 4.4616816845
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1016002989
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.3619428831
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 16.0215591091 19196723 19196722
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 16.0215458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 16.0211807958 16891317 11408345 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 16.0214578162 12929590
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 16.0216827153 11731420 19196723 14580682 19196722
MESH:D020149 Manganese Poisoning Estradiol 11.2719453300
MESH:D020149 Manganese Poisoning Tamoxifen 11.2719453300
MESH:D008545 Melanoma Doxorubicin 4.6516827129
MESH:D008545 Melanoma sodium arsenite 4.6516487513 19082730
MESH:D008545 Melanoma Tamoxifen 4.6512393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 3.7815990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.1719513568
MESH:D008654 Mesothelioma Doxorubicin 2.8917638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.3716801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.1315792986
MESH:D009041 Motion Sickness Dextroamphetamine 5.111613127
MESH:D052016 Mucositis Doxorubicin 4.3817415656
MESH:D009101 Multiple Myeloma arsenic trioxide 7.0111468182 19417148 14977855 15949261 19549372
MESH:D009101 Multiple Myeloma S-(dimethylarsino)-glutathione 7.0119417148
MESH:D009135 Muscular Diseases pirinixic acid 3.1116239165
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.2618349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.9016882451 16105982
MESH:D009203 Myocardial Infarction Doxorubicin 8.4315857846 19429709
MESH:D009203 Myocardial Infarction Genistein 8.4317141266
MESH:D009203 Myocardial Infarction pirinixic acid 8.4319151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 12.3716810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 12.3717141266
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 12.3716411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.0717484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 8.9918551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 8.997678174 18551238
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.5716624393
MESH:D009362 Neoplasm Metastasis Doxorubicin 5.2918259882
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.2919393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.3719410462
MESH:D009369 Neoplasms 4-phenylbutyric acid 13.5219116145
MESH:D009369 Neoplasms alitretinoin 13.5216946489
MESH:D009369 Neoplasms Diethylstilbestrol 13.5215313581
MESH:D009369 Neoplasms pirinixic acid 13.5217405874
MESH:D009369 Neoplasms sodium arsenite 13.5211559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.2720056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 9.5519196722
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 9.5519189210 19196722 19200415
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3317289903
MESH:D009401 Nephrosis Doxorubicin 4.3716636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.0317954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 8.1618481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 8.1615640375 16889571
MESH:D009421 Nervous System Malformations Diethylstilbestrol 20.2811399458
MESH:D009421 Nervous System Malformations Estradiol 20.2816427766 11399458
MESH:D009421 Nervous System Malformations Genistein 20.2816427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 20.2814600291
MESH:D009436 Neural Tube Defects arsenic trioxide 10.8110525206
MESH:D009436 Neural Tube Defects sodium arsenite 10.8112854658
MESH:D009436 Neural Tube Defects Tetrahydrocannabinol 10.8119040278
MESH:D009447 Neuroblastoma Doxorubicin 3.0515555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.5418514411
MESH:D009759 Nystagmus, Pathologic Astemizole 6.056135121
MESH:D009765 Obesity pirinixic acid 1.7120558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 13.1216049721 12819281
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 13.1216049721
MESH:D009784 Occupational Diseases 4-amino-2,6-dinitrotoluene 13.1214694615
MESH:D010018 Osteomalacia Phenobarbital 3.9617016548
MESH:D010024 Osteoporosis Genistein 3.0019401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.7116169203
MESH:D012516 Osteosarcoma Doxorubicin 3.7915930896
MESH:D010051 Ovarian Neoplasms arsenic trioxide 10.1219769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Estradiol 10.1219401270
MESH:D010051 Ovarian Neoplasms Genistein 10.1219005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 10.1217306315 15276417
MESH:D010146 Pain Acetaminophen 2.0816870215
MESH:D010190 Pancreatic Neoplasms 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone 7.8212384795
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 7.8215580305
MESH:D010190 Pancreatic Neoplasms Phenobarbital 7.8216965848
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3111578682
MESH:D010235 Paraganglioma arsenic trioxide 3.7919927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.8312520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.7417983394
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.7514722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.2715687265 16977796
MESH:D010997 Pleural Neoplasms Doxorubicin 4.7417638057
MESH:D017499 Porokeratosis alitretinoin 5.5916144296
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.1718163543
MESH:D011230 Precancerous Conditions Cyclosporine 7.8412371664
MESH:D011230 Precancerous Conditions Phenobarbital 7.842563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 8.2217184923
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 8.2211399792 11118676 11896295 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5220887781
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.0319131511
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.0315046698 17136230 15846301
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0315749863 15897917 16868541 18437689 16888761 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 2.0316740699
MESH:D011471 Prostatic Neoplasms Genistein 2.0315256057 16925846 15378649
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.0316039940
MESH:D011471 Prostatic Neoplasms Tamoxifen 2.0315067354
MESH:D011537 Pruritus Ethinyl Estradiol 2.9115861022 16919318
MESH:D019310 Pseudolymphoma Phenobarbital 4.0812752131
MESH:D011565 Psoriasis Cyclosporine 2.0816882103
MESH:D051437 Renal Insufficiency Doxorubicin 3.8317922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.1819058328
MESH:D012135 Respiratory Sounds Vehicle Emissions 4.8218950799
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.4518990726
MESH:D012221 Rhinitis, Allergic, Perennial Astemizole 5.0110822083
MESH:D012509 Sarcoma Doxorubicin 3.6417203757 15625365 15675481 16767912 17710206 18313854
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.0016646077
MESH:D012512 Sarcoma, Ewing's Doxorubicin 9.0016326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.3817846226
MESH:D012640 Seizures 2,4-dinitrotoluene 8.1918551238
MESH:D012640 Seizures 2,6-dinitrotoluene 8.1918551238
MESH:D012640 Seizures Phenobarbital 8.193137016 11442880 4039156 16876388
MESH:D003294 Seizures, Febrile Phenobarbital 4.416407741
MESH:D012878 Skin Neoplasms Doxorubicin 11.9115692506
MESH:D012878 Skin Neoplasms sodium arsenite 11.9118572023 19524636
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 11.918532709
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 11.9116192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.1716767912 17203757 15625365
MESH:D013088 Spermatocele Diethylstilbestrol 17.7316709447 16002989
MESH:D013088 Spermatocele Ethinyl Estradiol 17.7316709447
MESH:D013088 Spermatocele Tamoxifen 17.7316709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 3.6319457130
MESH:D016135 Spinal Dysraphism sodium arsenite 3.4812854658
MESH:D013158 Splenic Diseases Dimethylnitrosamine 4.8512587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.5917007042
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 2.5916033868
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.2511994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.4912697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 10.2519014326
MESH:D013964 Thyroid Neoplasms Doxorubicin 10.2517909728 16010429
MESH:D013964 Thyroid Neoplasms Phenobarbital 10.251399818
MESH:D013978 Tibial Fractures Estradiol 4.2719048282
MESH:D016171 Torsades de Pointes arsenic trioxide 9.2815213294
MESH:D016171 Torsades de Pointes Astemizole 9.288256756 9583453
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 25.5116049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 25.5116049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 25.5120435036 12973940 11780464 12845720
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 25.5116452187 16712894 17306315
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 25.5117653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 25.5116712894 11723127 17306315 16452187
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 25.5116712894 8653321 17572228
MESH:D001749 Urinary Bladder Neoplasms Vehicle Emissions 25.5111144890
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 10.6310091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 10.6310091137
MESH:D014581 Urticaria Acetaminophen 7.7910982225
MESH:D014581 Urticaria Astemizole 7.793097109 3080510 2859714 2565098 2885854 1976298 3134034 2147912 1683191 2568013 2568189 2883202
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.3716175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.3711813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.7514652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 8.1915809267 16690809
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 8.1914692618
MESH:D014605 Uveitis Cyclosporine 3.571336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.0416513791 16002989
MESH:D014652 Vascular Diseases sodium arsenite 4.0217056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.1812125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.1814671159 15869587
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 3.8317678736 17638931 17334414 16364871
MESH:D014717 Vertigo Astemizole 6.053105558
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.8315886252
MESH:D014985 Xerophthalmia Cyclosporine 4.0317120751
Pathway ID Pathway Name
KEGG:04141 Protein processing in endoplasmic reticulum
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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