AutismKB 2.0

Annotation Detail for STARD10


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Basic Information Top
Gene Symbol:STARD10 ( MGC14401,NY-CO-28,PCTP2,SDCCAG28 )
Gene Full Name: StAR-related lipid transfer (START) domain containing 10
Band: 11q13
Quick LinksEntrez ID:10809; OMIM: NA; Uniprot ID:PCTL_HUMAN; ENSEMBL ID: ENSG00000214530; HGNC ID: 10666
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of STARD10 proteinaffects expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of STARD10 mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in decreased expression of STARD10 mRNAdecreases expression 20106945
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of STARD10 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of STARD10 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of STARD10 mRNAdecreases expression 17108234
D015741 Metribolone Metribolone results in increased expression of STARD10 mRNAincreases expression 17010196
C406082 monomethylarsonous acid [monomethylarsonous acid affects the acetylation of HIST3H3 protein] which affects the methylation of STARD10 promoteraffects acetylation|affects methylation 18448484
C017947 sodium arsenite [sodium arsenite affects the acetylation of HIST3H3 protein] which affects the methylation of STARD10 promoteraffects acetylation|affects methylation 18448484
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of STARD10 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1814514962 15322242 11752688
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7116835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.0815276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 5.2817306315 16712894
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8015885639
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.6820435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.0818705752 16124888 10355542 16097048 3786805 15700767 16192424 15721981 16050911 15673190 16227642 16011737
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.8012619106 12907637 21507988
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 4.8018788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 4.8015276417 17306315 16507464
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.4318572023
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4916120746 18850075 18670907
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.2712371664
MESH:D002471 Cell Transformation, Neoplastic monomethylarsonous acid 12.2719716837
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 12.2720056578 19524636
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3816835633
MESH:D002779 Cholestasis Cyclosporine 8.3719486331
MESH:D002779 Cholestasis Ethinyl Estradiol 8.3716105132 15861022 17681005 16919318 17333356 11677210 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1916354765 12621046 15340226 8697196 15668235
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2717141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 20055451 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 3.927440962 16177239 15027814 6623471 10092053 19085960 10915739 3732212 4309450 11566570 2869522 3786805 17522070 19336974 15968718 15998439 21278145 7120509 7179309 6884620 9327722 16227642
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.9220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6112711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2815322242 16714409 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4712538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.259294722 10568697
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 14.5117595544 12795759 19224547 12631006 16239168 61145 16045604 15959796
MESH:D005234 Fatty Liver Cyclosporine 14.5119224547
MESH:D005234 Fatty Liver Ethinyl Estradiol 14.5115345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Carbon Tetrachloride 16.5818705752
MESH:D005355 Fibrosis Cyclosporine 16.5812168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 16.5820067830
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.0216452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.568708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4411294989 10048152
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.8819900420 19110552
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2016120746 15340226 12621046
MESH:D006689 Hodgkin Disease sodium arsenite 3.3612676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4218606429 16959395 15340226 8697196 16354765
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.8716899240
MESH:D006973 Hypertension Cyclosporine 5.2110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.3915338365
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 7.1617937319
MESH:D007248 Infertility, Male sodium arsenite 7.1612646999 15346721
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9612200463 12878042
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5816580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8215604871
MESH:D007674 Kidney Diseases Cyclosporine 6.448314463 10903974 18776723
MESH:D007674 Kidney Diseases sodium arsenite 6.4420008137
MESH:D007680 Kidney Neoplasms Cyclosporine 2.9312371664
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9216221502 16943688 21278145 17157831 17174718 11903743 17334410 11408273 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.3414512876 18395914 14748882 18210741 17900296 18376398 12445421 18205269 17640975 12898905 12649538 18279442 17525996 17761835 18006644 15818738 18420326 15996030 12667390 10355542 16015684 16248980 18395095 17708605 12609069 17714472 17976157 17922224 17481882 17721639 17631135 15673190 18418968 18339082 15925388 18412020 16011737 12741479 18472332 12586293 18166357 16638106 18277467 15730626 18263696 17557913 14716833 15338365 12445418 15362042 17823541 17805973 20821823 15123356 14620537 18251166 14716496 12546737 18429990 12632514 15650968 15931870 12389079 18054572 16027843 17766677 18481824 18187930 15893842 15370692 12632512 12958196 16116963 18156304 15052691 14724832 17944888 18472094 13678700 15057751 17869086 17698563 16192424 15876570 16136751 11481614 18705752 15959796 16033810 17565644 18317297 12666154 16097048
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.3412878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1316246199 15720792 16964402 15830285 17285989
MESH:D017093 Liver Failure Carbon Tetrachloride 4.4715123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.9216899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 11.3618177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 11.3619294768
MESH:D008113 Liver Neoplasms sodium arsenite 11.3615276417 16712894
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.3616984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 10.648603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.6412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.6412151625
MESH:D008171 Lung Diseases sodium arsenite 3.3219095001
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.5314755239
MESH:D008175 Lung Neoplasms sodium arsenite 3.5319931552 17306315 16712894 17077188 15276417
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.5311884234 19555203
MESH:D008545 Melanoma sodium arsenite 2.0619082730 16487513
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1616801185
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D009369 Neoplasms sodium arsenite 2.6011559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.9720056578
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5019348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4914600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.2912854658
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4917306315 15276417
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.4412371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311896295 11399792 11118676 11222880
MESH:D011471 Prostatic Neoplasms marker/mechanism 17013881
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.2616039940
MESH:D011537 Pruritus Ethinyl Estradiol 3.6516919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012871 Skin Diseases monomethylarsonous acid 3.4317431481
MESH:D012878 Skin Neoplasms sodium arsenite 5.9318572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.9316192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3216709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.9812854658
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2812697716
MESH:D001749 Urinary Bladder Neoplasms monomethylarsonous acid 5.7920375083
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.7917306315 11723127 16452187 16712894
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.9911813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D014605 Uveitis Cyclosporine 4.361336536
MESH:D014652 Vascular Diseases sodium arsenite 4.7617056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.8217120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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