AutismKB 2.0

Annotation Detail for SRCAP


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Basic Information Top
Gene Symbol:SRCAP ( DOMO1,EAF1,FLJ44499,KIAA0309,SWR1 )
Gene Full Name: Snf2-related CREBBP activator protein
Band: 16p11.2
Quick LinksEntrez ID:10847; OMIM: 611421; Uniprot ID:SRCAP_HUMAN; ENSEMBL ID: ENSG00000080603; HGNC ID: 16974
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Pathway IDPathway Name
P00057Wnt signaling pathway
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D002251 Carbon Tetrachloride Carbon Tetrachloride results in decreased expression of SRCAP mRNAdecreases expression 17484886
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.6916011737 15700767 18705752 15673190 10355542 16050911 16097048 15721981 16124888 16227642 3786805 16192424
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 1.8718788625
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 2.1516227642 2869522 19085960 7179309 11566570 3786805 17522070 10092053 7440962 15027814 4309450 15998439 15968718 3732212 16177239 7120509 9327722 6623471 19336974 21278145 10915739 6884620
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.7915959796 12795759 16239168 12631006 17595544 61145 19224547 16045604
MESH:D005355 Fibrosis Carbon Tetrachloride 4.3618705752
MESH:D006505 Hepatitis Carbon Tetrachloride 4.3819110552 19900420
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.6216899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.9915338365
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 3.0611408273 11903743 17334410 16221502 21278145 17157831 16239168 17174718 16943688
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7618317297 18251166 12632514 14512876 10355542 15370692 16027843 18166357 12445421 12666154 17640975 17823541 15362042 18376398 13678700 17976157 17721639 17481882 17708605 18054572 15123356 17714472 16116963 16015684 15673190 12445418 17761835 11481614 17525996 15052691 12586293 15650968 18205269 18277467 16248980 17922224 18279442 15931870 18705752 18395095 15876570 18420326 17944888 16136751 18418968 18472332 12958196 18472094 18339082 18481824 18429990 17869086 15057751 18263696 18156304 15959796 18187930 16638106 17766677 17900296 12667390 16097048 17631135 12389079 16192424 17557913 18210741 12649538 15730626 14748882 12741479 15893842 17565644 18412020 17805973 12898905 15338365 17698563 15996030 15925388 12632512 14724832 16033810 14620537 18006644 15818738 14716496 20821823 12609069 18395914 16011737 12546737 14716833
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1717285989 15720792 16246199 16964402 15830285
MESH:D017093 Liver Failure Carbon Tetrachloride 5.0715123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 4.2616899240 14706259
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 2.3719294768
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.9115583823 12014681
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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