Annotation Detail for TSPAN9
Basic Information Top
| Gene Symbol: | TSPAN9 ( NET-5,NET5,PP1057 ) |
|---|---|
| Gene Full Name: | tetraspanin 9 |
| Band: | 12p13.33-p13.32 |
| Quick Links | Entrez ID:10867; OMIM: 613137; Uniprot ID:TSN9_HUMAN; ENSEMBL ID: ENSG00000011105; HGNC ID: 21640 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of TSPAN9 mRNA | affects expression | 17562736 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in increased expression of TSPAN9 mRNA | increases expression | 15003993 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TSPAN9 mRNA | affects binding|decreases expression|increases activity | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 12392966 16081117 19164858 11287661 15968718 19739265 15619225 12958197 10774834 19416960 19923254 12705907 19420014 10915739 12594235 18071297 17562736 16227642 2444490 16109766 11421492 16393943 16485898 10663392 19370779 14725611 17522070 11529661 12540782 18713872 11743745 17906064 16177239 16781746 14986274 14550746 11834606 19085960 11739529 12153990 11461765 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 19236843 20131406 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 19176532 18467677 16221962 19772884 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 12587719 15629191 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12587719 16611625 19014921 16610002 19784758 11587558 12969438 19460945 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 20007298 15890375 16377806 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 2.86 | 8532709 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |